Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Kazuki Kawakami"'
Autor:
Takuma Yonemura, Rie Yazawa, Miwa Haranaka, Kazuki Kawakami, Masayuki Takanuma, Takumi Kanzo, Dimitris Stefanidis, Yasumasa Arai
Publikováno v:
BMC Pharmacology and Toxicology, Vol 23, Iss 1, Pp 1-11 (2022)
Abstract Background FKB327 has been developed as a biosimilar of the adalimumab reference product (RP). We compared the pharmacokinetics (PK), safety, and immunogenicity of FKB327 with those of the adalimumab RP after a single dose by subcutaneous (S
Externí odkaz:
https://doaj.org/article/eeebeba3510b413bb1922f2cbe0455e9
Autor:
Mitsuru Yashiro, Masaki Ohya, Toru Mima, Yuri Nakashima, Kazuki Kawakami, Tomohiro Sonou, Koichi Tatsuta, Yukiko Yamano, Shigeo Negi, Takashi Shigematsu
Publikováno v:
Immunity, Inflammation and Disease, Vol 8, Iss 2, Pp 228-235 (2020)
Abstract Introduction We previously reported that fibroblast growth factor 23 (FGF23)‐klotho signaling plays a role in B cell immunity. Despite high serum levels of FGF23, a decline in immunity is frequently observed in patients on hemodialysis (HD
Externí odkaz:
https://doaj.org/article/37e8676dcf67476192ea5211da3efb8c
Publikováno v:
BMC Pharmacology and Toxicology, Vol 20, Iss 1, Pp 1-8 (2019)
Abstract Background/objective FKB327 is a biosimilar of the adalimumab reference product (RP). The primary objective was to assess the relative bioavailability of FKB327 after a single subcutaneous (SC) dose via prefilled syringe (PFS), auto-injector
Externí odkaz:
https://doaj.org/article/293fd0f9faa04003b0974c0a432efd63
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-15 (2018)
Abstract Fibroblast growth factor 23 (FGF23) plays critical roles in phosphate handling and vitamin D metabolism in the kidney. However, the effector cells of FGF23 in the kidney remain unclear. αKlotho, a putative enzyme possessing β-glucuronidase
Externí odkaz:
https://doaj.org/article/e06b4d92a8fd4f5e8d16524faf5daa4f
Autor:
Masato Komai, Hiroyuki Tanaka, Koichi Nagao, Masayuki Ishizaki, Daisuke Kajiwara, Toru Miura, Hiroshi Ohashi, Tomoko Haba, Kazuki Kawakami, Eiji Sawa, Osamu Yoshie, Naoki Inagaki, Hiroichi Nagai
Publikováno v:
Journal of Pharmacological Sciences, Vol 112, Iss 2, Pp 203-213 (2010)
CC-chemokine receptor 3 (CCR3) is a chemokine receptor for which major ligands, CC-chemokine ligand (CCL) 11, CCL24, and CCL26, are known to be involved in chemotaxis for eosinophils. In the present study, we evaluated the effect of a low molecular w
Externí odkaz:
https://doaj.org/article/81343e8e47f946f7bd423ca42ef55b94
Autor:
Takahiro Sawada, Daiki Arai, Xuefeng Jing, Kenryo Furushima, Qingfa Chen, Kazuki Kawakami, Hideyuki Yokote, Masayasu Miyajima, Kazushige Sakaguchi
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0128826 (2015)
Ephs and FGFRs belong to a superfamily of receptor tyrosine kinases, playing important roles in stem cell biology. We previously reported that EphA4 and FGFR form a heterodimer following stimulation with ligands, trans-activating each other and signa
Externí odkaz:
https://doaj.org/article/1bcf04b0097f4270b506066490948ad3
Autor:
Qingfa Chen, Daiki Arai, Kazuki Kawakami, Takahiro Sawada, Xuefeng Jing, Masayasu Miyajima, Syu-Ichi Hirai, Kazushige Sakaguchi, Kenryo Furushima
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0126942 (2015)
In mouse cerebral corticogenesis, neurons are generated from radial glial cells (RGCs) or from their immediate progeny, intermediate neuronal precursors (INPs). The balance between self-renewal of these neuronal precursors and specification of cell f
Externí odkaz:
https://doaj.org/article/07ab14eed95b4d489e768e0e7b361a8e
Autor:
Kazuki Kawakami, Masaki Ohya, Mitsuru Yashiro, Tomohiro Sonou, Shuto Yamamoto, Yuri Nakashima, Takuro Yano, Yusuke Tanaka, Koichi Ishida, Seiichi Kobashi, Takashi Shigematsu, Shin-ichi Araki
Publikováno v:
Calcified Tissue International.
Autor:
Teppei Suzuki, Masaaki Ito, Koki Uno, Kazuki Kawakami, Noriaki Kawakami, Hiroko Matsumoto, Toshiki Saito
Publikováno v:
Spine Deformity. 9:529-538
A retrospective comparative study. This study compares the effect of age at the time of surgery on clinical and health-related quality-of-life (HRQoL) outcomes at 10-year follow-up in pediatric patients with congenital scoliosis (CS). Several studies
Autor:
Koichi Tatsuta, Tomohiro Sonou, Toru Mima, Yukiko Yamano, Takashi Shigematsu, Masaki Ohya, Yuri Nakashima, Shigeo Negi, Kazuki Kawakami, Mitsuru Yashiro
Publikováno v:
Immunity, Inflammation and Disease, Vol 8, Iss 2, Pp 228-235 (2020)
Immunity, Inflammation and Disease
Immunity, Inflammation and Disease
Introduction We previously reported that fibroblast growth factor 23 (FGF23)‐klotho signaling plays a role in B cell immunity. Despite high serum levels of FGF23, a decline in immunity is frequently observed in patients on hemodialysis (HD); thus,