Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Kazuki Hasegawa"'
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Hyaluronan synthesis inhibitor 4-methylumbelliferone (4-MU) is a candidate of radiosensitizers which enables both anti-tumour and anti-metastasis effects in X-ray therapy. The curative effects under such 4-MU administration have been investi
Externí odkaz:
https://doaj.org/article/70e6ccd9f13047efa76fb91d40b2720f
Autor:
Tomohiro Katagiri, Yoshio Ohyama, Hideo Miyamoto, Yuki Egawa, Toshiaki Moriki, Kazuki Hasegawa
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-10 (2020)
Abstract Background The prognosis of advanced oral cancer remains dismal. While multimodal therapy is beneficial, maintaining the quality of life of long-term survivors is important. Therefore, risk-adapted treatment regimens need to be designed. We
Externí odkaz:
https://doaj.org/article/8dd37d057d3e4521bd20a815f0a64c12
Autor:
Kazuki Hasegawa, Ryo Saga, Kentaro Ohuchi, Yoshikazu Kuwahara, Kazuo Tomita, Kazuhiko Okumura, Tomoaki Sato, Manabu Fukumoto, Eichi Tsuruga, Yoichiro Hosokawa
Publikováno v:
Cells, Vol 11, Iss 23, p 3780 (2022)
Radioresistant (RR) cells are poor prognostic factors for tumor recurrence and metastasis after radiotherapy. The hyaluronan (HA) synthesis inhibitor, 4-methylumbelliferone (4-MU), shows anti-tumor and anti-metastatic effects through suppressing HA s
Externí odkaz:
https://doaj.org/article/e8f4a19d15614a2992999b86da318b05
Autor:
Kentaro Ohuchi, Ryo Saga, Kazuki Hasegawa, Eichi Tsuruga, Yoichiro Hosokawa, Manabu Fukumoto, Kazuhiko Okumura
Publikováno v:
Biomed Rep
Radioresistant cancer cells lead to poor prognosis after radiotherapy. However, the mechanisms underlying cancer cell radioresistance have not been fully elucidated. Thus, the DNA damage response of clinically relevant radioresistant oral squamous ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50a31169dae750813c7e5efd9258794d
https://europepmc.org/articles/PMC10011949/
https://europepmc.org/articles/PMC10011949/
Publikováno v:
The Journal of General and Applied Microbiology.
Autor:
Ryo Saga, Yusuke Matsuya, Hikari Sato, Kazuki Hasegawa, Hideki Obara, Fumio Komai, Hironori Yoshino, Masahiko Aoki, Yoichiro Hosokawa
Publikováno v:
Radiotherapy and Oncology. 181:109444
Autor:
KAZUKI HASEGAWA1, RYO SAGA1 sagar@hirosaki-u.ac.jp, REI TAKAHASHI1, ROMAN FUKUI1, MITSURU CHIBA2, KAZUHIKO OKUMURA3, EICHI TSURUGA1, YOICHIRO HOSOKAWA1 hosokawa@hirosaki-u.ac.jp
Publikováno v:
Oncology Letters. Apr2020, Vol. 19 Issue 4, p2801-2808. 8p.
Autor:
Hiroshi Takatsuki, Kazuo Nakamura, Junya Yano, Shin-ichi Sakai, Kazuki Hasegawa, Misuzu Asari, Harumi Koizumi
Publikováno v:
Material Cycles and Waste Management Research. 31:273-284
Autor:
Hikari Sato, Yoichiro Hosokawa, Mitsuki Tanaka, Fumiki Ito, Kazuki Hasegawa, Masahiko Aoki, Ryo Saga
Publikováno v:
Oncology Letters
BackgroundStereotactic body radiotherapy (SBRT) has extensively attracted attention as an effective treatment for patients with early-stage non-small cell lung cancers (NSCLCs). However, the factors affecting prognosis after SBRT have not been fully
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1edf81ae1d5f1e8cd4580654c5b39ce
https://doi.org/10.21203/rs.3.rs-968668/v1
https://doi.org/10.21203/rs.3.rs-968668/v1
Publikováno v:
Journal of Radiation Research
In radiotherapy, cancer stem cells (CSCs) are well recognized as one of the radioresistant cell types. Even in a small subpopulation, CSCs may have an influence on tumor control probability, represented by cell killing after irradiation. However, the