Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Kazuki Akazawa"'
Autor:
Masafumi Minoshima, Yuki Konishi, Fuminori Sugihara, Kazuya Kikuchi, Kazuki Akazawa, Tatsuya Nakamura, Atsuya Okunishi
Publikováno v:
Bulletin of the Chemical Society of Japan.
Cathepsin K is a protease expressed in osteoclasts that degrades bone tissue, such as type I collagen fibers. Overexpression of cathepsin K is involved in osteoporosis, rheumatoid arthritis, and bo...
Autor:
Hisashi Matsushita, Shin Mizukami, Hiroaki Mukai, Tatsuya Nakamura, Rena Akimoto, Fuminori Sugihara, Kazuya Kikuchi, Masafumi Minoshima, Kazuki Akazawa
Publikováno v:
Angewandte Chemie International Edition. 57:16742-16747
In vivo multicolor imaging is important for monitoring multiple biomolecular or cellular processes in biology. 19 F magnetic resonance imaging (MRI) is an emerging in vivo imaging technique because it can non-invasively visualize 19 F nuclei without
Publikováno v:
Chemical Communications. 54:11785-11788
Activatable 19F MRI nanoprobes for sensing caspase-1 activity were developed. Tandem repetition of substrate peptide sequences improved the turn-on response of nanoprobes, allowing detection of caspase-1 activity by 19F MRI. In vivo immune response w
Autor:
Kazuki, Akazawa, Fuminori, Sugihara, Tatsuya, Nakamura, Hisashi, Matsushita, Hiroaki, Mukai, Rena, Akimoto, Masafumi, Minoshima, Shin, Mizukami, Kazuya, Kikuchi
Publikováno v:
Angewandte Chemie (International Ed. in English)
In vivo multicolor imaging is important for monitoring multiple biomolecular or cellular processes in biology. 19F magnetic resonance imaging (MRI) is an emerging in vivo imaging technique because it can non‐invasively visualize 19F nuclei without
Publikováno v:
Bioconjugate chemistry. 29(5)
Highly sensitive imaging of enzymatic activities in the deep tissues of living mammals provides useful information about their biological functions and for developing new drugs; however, such imaging is challenging.