Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Kazuki, Sone"'
Autor:
Kazuki Sone, Yuka Sakamaki, Satomi Hirose, Mai Inagaki, Masanori Tachikawa, Daisuke Yoshino, Kenichi Funamoto
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Blood glucose levels fluctuate during daily life, and the oxygen concentration is low compared to the atmosphere. Vascular endothelial cells (ECs) maintain vascular homeostasis by sensing changes in glucose and oxygen concentrations, resulti
Externí odkaz:
https://doaj.org/article/814d41c64c8f4161ac08be8f5fefaf45
Autor:
Naoyuki Takahashi, Daisuke Yoshino, Ryuji Sugahara, Satomi Hirose, Kazuki Sone, Jean-Paul Rieu, Kenichi Funamoto
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Vascular endothelial cells (ECs) respond to mechanical stimuli caused by blood flow to maintain vascular homeostasis. Although the oxygen level in vascular microenvironment is lower than the atmospheric one, the cellular dynamics of ECs unde
Externí odkaz:
https://doaj.org/article/33d15f209bdd49aaaa445b35c0b67142
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Dendritic cells (DCs) play a key role to modulate anti-cancer immunity in the tumor microenvironment (TME). They link innate to adaptive immunity by processing and presenting tumor antigens to T cells thereby initiating an anti-tumor response. Howeve
Externí odkaz:
https://doaj.org/article/72ffb178714541a7b6c9583c288bed34
Autor:
Satomi Hirose, Yugo Tabata, Kazuki Sone, Naoyuki Takahashi, Daisuke Yoshino, Kenichi Funamoto
Publikováno v:
Cell Adhesion & Migration, Vol 15, Iss 1, Pp 272-284 (2021)
The collective migration of vascular endothelial cells plays important roles in homeostasis and angiogenesis. Oxygen tension in vivo is a key factor affecting the cellular dynamics. We previously reported hypoxic conditions promote the internalizatio
Externí odkaz:
https://doaj.org/article/3ee5040b4e084791a5006f4eebaf8de8
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Topological phenomena appear in non-Hermitian systems but the fundamental principles of the edge modes remain less understood. Here, Sone et al. report robust gapless edge modes due to topological structure around an exceptional point rather than bul
Externí odkaz:
https://doaj.org/article/1f09a0b67f92424794110b2bd9d2ef27
Autor:
Kazuki Sone, Tetsuya Oguri, Takehiro Uemura, Akira Takeuchi, Satoshi Fukuda, Osamu Takakuwa, Ken Maeno, Kensuke Fukumitsu, Yoshihiro Kanemitsu, Hirotsugu Ohkubo, Masaya Takemura, Yutaka Ito, Akio Niimi
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-9 (2019)
Abstract Background Docetaxel is a widely used cytotoxic agent for treatments of various cancers. The ATP binding cassette (ABC) transporter / multidrug resistance protein (MRP) ABCC10/MRP7, involved in transporting taxanes, has been associated with
Externí odkaz:
https://doaj.org/article/9db115492e1b43d0a3d1002f6aa7b2bc
Publikováno v:
Physical Review Research, Vol 4, Iss 2, p 023211 (2022)
Synchronization of coupled oscillators is a ubiquitous phenomenon found throughout nature. Its robust realization is crucial to our understanding of various nonlinear systems, ranging from biological functions to electrical engineering. On another fr
Externí odkaz:
https://doaj.org/article/cca998f677ac4aa3ab24af74311e7232
Autor:
Sosuke, Arakawa, Makoto, Nakao, Kazuki, Sone, Shuntaro, Hayashi, Masahiro, Sugihara, Yuya, Hirata, Mamiko, Kuriyama, Norihisa, Takeda, Kazuhiro, Ohtakara, Yoshimi, Horikawa, Hideki, Muramatsu
Publikováno v:
Internal Medicine. 62:1049-1054
A 77-year-old man presented with a 1-month history of cough, pharyngeal discomfort, and weight loss. Chest radiography revealed a mass shadow in the right upper lung field. Bronchoscopy showed multiple white nodules along the tracheal cartilage ring.
Autor:
Kazuki Sone, Ken Maeno, Ayako Masaki, Eiji Kunii, Osamu Takakuwa, Yusuke Kagawa, Akira Takeuchi, Satoshi Fukuda, Takehiro Uemura, Kensuke Fukumitsu, Yoshihiro Kanemitsu, Hirotsugu Ohkubo, Masaya Takemura, Yutaka Ito, Tetsuya Oguri, Hiroshi Inagaki, Akio Niimi
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Objectives: Small cell lung cancer (SCLC) is an aggressive and highly metastatic lung cancer subtype. Nestin is a member of the intermediate filament family and serves as a potential proliferative and multipotency marker in neural progenitor and stem
Externí odkaz:
https://doaj.org/article/014a37ba69584ab392682894e8bb54ca
Autor:
Yusuke Kagawa, Kazuki Sone, Tetsuya Oguri, Minoru Horiuchi, Satoshi Fukuda, Takehiro Uemura, Osamu Takakuwa, Ken Maeno, Kennsuke Fukumitsu, Yoshihiro Kanemitsu, Tomoko Tajiri, Hirotsugu Ohkubo, Masaya Takemura, Yutaka Ito, Akio Niimi
Publikováno v:
Respiratory Investigation. 60:393-399
S-1, an oral fluoropyrimidine derivative, is widely used for the treatment of several solid tumors. However, there are no predictive markers for its effectiveness.We retrospectively screened 108 patients with advanced non-small cell lung cancer (NSCL