Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Kazuki, Fukuda"'
Autor:
Masaji Sakaguchi, Shota Okagawa, Yuma Okubo, Yuri Otsuka, Kazuki Fukuda, Motoyuki Igata, Tatsuya Kondo, Yoshifumi Sato, Tatsuya Yoshizawa, Takaichi Fukuda, Kazuya Yamagata, Weikang Cai, Yu-Hua Tseng, Nobuo Sakaguchi, C. Ronald Kahn, Eiichi Araki
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
The insulin signalling cascade can be inhibited by phosphatases, including Ser/Thr protein phosphatase 2A (PP2A). Here the authors show that Alpha4, a regulator of the PP2A catalytic subunit, modulates insulin receptor tyrosine phosphorylation via th
Externí odkaz:
https://doaj.org/article/5e9e60d829fc411da353c7feb24250ca
Autor:
Kento Nakagawa, Saeko Kawashima, Kazuki Fukuda, Nobuaki Mizuguchi, Tetsuro Muraoka, Kazuyuki Kanosue
Publikováno v:
Frontiers in Human Neuroscience, Vol 17 (2023)
Interlimb coordination involving cyclical movements of hand and foot in the sagittal plane is more difficult when the limbs move in opposite directions compared with the same direction (directional constraint). Here we first investigated whether the
Externí odkaz:
https://doaj.org/article/71027f9f45d44979b114a31bafca718f
Publikováno v:
Journal of Diabetes Investigation, Vol 13, Iss 12, Pp 1958-1960 (2022)
Externí odkaz:
https://doaj.org/article/52ee58d2d3754d5e9f43b8985470bebd
Autor:
Kazumi Matsushima-Nagata, Takeshi Matsumura, Yuki Kondo, Kensaku Anraku, Kazuki Fukuda, Mikihiro Yamanaka, Masahiro Manabe, Tetsumi Irie, Eiichi Araki, Hiroyuki Sugiuchi
Publikováno v:
Biomolecules, Vol 13, Iss 3, p 468 (2023)
Remnant lipoproteins (RLs), which are typically present at high concentrations in patients with type 2 diabetes mellitus (T2DM), are associated with cardiovascular disease (CVD). Although an RL cholesterol homogeneous assay (RemL-C) is available for
Externí odkaz:
https://doaj.org/article/e5bceaec729947bfb818d6b31e873879
Autor:
China, Ogura, Yoshikazu, Ogawa, Haruna, Kameoka, Kazuki, Fukuda, Mina, Takahashi, Kenjirou, Aogi
Publikováno v:
Gan to kagaku ryoho. Cancerchemotherapy. 49(12)
Palbociclib(PAL), which is a small molecule with inhibitory activity against cyclin-dependent kinase 4/6, is used in endocrine combined therapy for the treatment of estrogen receptor(ER)-positive and HER2-negative inoperable and recurrent breast canc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8dee1823e9acd4d38611e87703f567e8
https://pubmed.ncbi.nlm.nih.gov/36539246
https://pubmed.ncbi.nlm.nih.gov/36539246
Autor:
GIORGIO BASILE, AMEDEO VETERE, JIANG HU, OLUWASEUN IJADUOLA, DARIO F. DE JESUS, KAZUKI FUKUDA, AMIRA M. ELTONY, ANDY YUN, AMIT CHOUDHARY, BRIDGET WAGNER, ROHIT KULKARNI
Publikováno v:
Diabetes. 71
The discovery of SerpinB1 as an inducer of human β-cell proliferation pointed to acinar cell-derived proteases such as pancreatic elastase (PE) being involved in regulating β-cell viability. Indeed, we observed that expression of a major form of PE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6861a22c5ac404e54e9b4ec0ac0d23cb
https://doi.org/10.2337/db22-247-lb
https://doi.org/10.2337/db22-247-lb
Publikováno v:
Japanese Journal of Applied Physics. 62:SC1010
The doping technique is vital for applying two-dimensional (2D) materials such as transition metal dichalcogenide (TMDC)-based field effect transistors (FETs), which can control the channel polarity and improve the performance. However, as convention
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ecbf2c6780efd10e059dde9843bdf0d
https://doi.org/10.35848/1347-4065/aca67e
https://doi.org/10.35848/1347-4065/aca67e
Autor:
Shota Okagawa, Junji Kawashima, Tatsuya Kondo, Motoyuki Igata, Kazuki Fukuda, Eiichi Araki, Yuma Okubo, Masaji Sakaguchi
Publikováno v:
Diabetes. 70
Insulin and IGF1 signaling initiate Tyr phosphorylation of IR/IGF1R and adaptor IRSs, leading to Ser/Thr phosphorylation of PI3K/AKT and MAPK/ERK pathways essential for the maintenance of brown and white adipose tissues (BAT and WAT). Lack of insulin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::458bb79f1092a4b5cebc76f72c24e3e1
https://doi.org/10.2337/db21-29-or
https://doi.org/10.2337/db21-29-or
Autor:
Tomohiko Kimura, Kazuki Orime, Kimitaka Shibue, Kazuki Fukuda, Dario F. De Jesus, Sevim Kahraman, Rohit N. Kulkarni
Publikováno v:
Diabetes. 69
While it is known that patients with nonalcoholic fatty liver disease exhibit enhanced insulin secretion, the factor(s) that contribute to this effect are not fully understood especially in nondiabetic subjects. Our aim was to examine crosstalk betwe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56581da0c8bdc2d5a090a4674f75ed90
https://doi.org/10.2337/db20-1811-p
https://doi.org/10.2337/db20-1811-p
Publikováno v:
Transportation Research Procedia. 34:267-274
The ability to find near-optimal traffic assignments for a very large network within a few days time will substantially contribute to reduce economic losses following major earthquake disasters. However, lack of efficient numerical tools and methodol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::558baa8e9da23d89abca1556a4d981e7
https://doi.org/10.1016/j.trpro.2018.11.041
https://doi.org/10.1016/j.trpro.2018.11.041