Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Kazuhisa Yamada"'
Autor:
Keigo Natsume, Taro Kominami, Kensuke Goto, Yoshito Koyanagi, Taiga Inooka, Junya Ota, Kenichi Kawano, Kazuhisa Yamada, Daishi Okuda, Kenya Yuki, Koji M. Nishiguchi, Hiroaki Ushida
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract The phenotypes of RP1-related inherited retinal dystrophies (RP1-IRD), causing autosomal dominant (AD) and autosomal recessive (AR) diseases, vary depending on specific RP1 variants. A common nonsense mutation near the C-terminus, c.5797 C >
Externí odkaz:
https://doaj.org/article/20870e1eb810428d8db509ca999f6c88
Autor:
Hiroaki Ushida, Ayana Suzumura, Kazuhisa Yamada, Hideyuki Shimizu, Atsuo Suzuki, Yusuke Ishikawa, Ryosuke Kikuchi, Koji M. Nishiguchi, Hiroki Kaneko
Publikováno v:
BMC Ophthalmology, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Purpose Vitreous humor (VH) is used for postmortem biochemical studies because it is well protected in an uncontaminated state even after death. The goal of this research was to investigate electrolyte concentrations in the VH from human eye
Externí odkaz:
https://doaj.org/article/fc10d631543a4e97bc44703d55c18948
Autor:
Kazuhisa Yamada, Akira Tazaki, Nanako Ushio-Watanabe, Yoshihiko Usui, Atsunobu Takeda, Masaaki Matsunaga, Ayana Suzumura, Hideyuki Shimizu, Hao Zheng, Nanang R. Ariefta, Masahiro Yamamoto, Hideaki Hara, Hiroshi Goto, Koh-Hei Sonoda, Koji M. Nishiguchi, Masashi Kato, Yoshifumi Nishikawa, Shinya Toyokuni, Hiroki Kaneko
Publikováno v:
Redox Biology, Vol 67, Iss , Pp 102890- (2023)
Toxoplasmosis is a major infectious disease, affecting approximately one-third of the world's population; its main clinical manifestation, ocular toxoplasmosis (OT), is a severe sight-threatening disease. Nevertheless, the diagnosis of OT is based on
Externí odkaz:
https://doaj.org/article/51daca73f1e740f5bad41ac0eb80d288
Autor:
Yasuki Ito, Mari Ito, Takeshi Iwase, Keiko Kataoka, Kazuhisa Yamada, Sayuri Yasuda, Hiroki Ito, Jun Takeuchi, Yuyako Nakano, Ai Fujita, Etsuyo Horiguchi, Yosuke Taki, Hiroshi Yatsuya, Hiroko Terasaki
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
Abstract Pachyvessels are pathologically dilated large choroidal vessels and are associated with the pathogenesis of several pachychoroid-related disorders, including central serous chorioretinopathy. We aimed to investigate the prevalence of and ris
Externí odkaz:
https://doaj.org/article/42249ff8523d49a8978476bfa9a63146
Autor:
Hideyuki Shimizu, Kei Takayama, Kazuhisa Yamada, Ayana Suzumura, Tomohito Sato, Yoshiaki Nishio, Masataka Ito, Hiroaki Ushida, Koji M Nishiguchi, Masaru Takeuchi, Hiroki Kaneko
Publikováno v:
Antioxidants, Vol 12, Iss 1, p 45 (2022)
The purpose of this study is to investigate the protective effect of dimethyl fumarate (DMF), the methyl-ester of fumaric acid, against blue-light (BL) exposure in retinal pigment epithelial (RPE) cells. ARPE-19 cells, a human RPE cell line, were cul
Externí odkaz:
https://doaj.org/article/99c08d040d5d40e8a078648940e76566
Autor:
Yoshito Koyanagi, Ai Fujita Sajiki, Hiroaki Ushida, Kenichi Kawano, Kosuke Fujita, Daishi Okuda, Mitsuki Kawabe, Kazuhisa Yamada, Ayana Suzumura, Shu Kachi, Hiroki Kaneko, Hiroyuki Komatsu, Yoshihiko Usui, Hiroshi Goto, Koji M. Nishiguchi
ObjectiveTo establish a metagenomic profiling method using long-read sequencing for clinical diagnosis of ocular inflammation and detect the etiologic virus of herpetic uveitis.DesignA retrospective, cross-sectional study.ParticipantsThe participants
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c546890244df8c7f69624e8208bb476f
https://doi.org/10.1101/2023.01.20.23284817
https://doi.org/10.1101/2023.01.20.23284817
Autor:
Ai Fujita Sajiki, Yoshito Koyanagi, Hiroaki Ushida, Kenichi Kawano, Kosuke Fujita, Daishi Okuda, Mitsuki Kawabe, Kazuhisa Yamada, Ayana Suzumura, Shu Kachi, Hiroki Kaneko, Hiroyuki Komatsu, Yoshihiko Usui, Hiroshi Goto, Koji M. Nishiguchi
ImportanceTorque teno virus positivity in the aqueous humor of uveitis patients could be associated with systemic immunodeficiency.ObjectiveWe explored the correlation between the presence of torque teno virus in the aqueous humor of uveitis patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c22e1b1900d315d74316476813b36c5f
https://doi.org/10.1101/2023.01.20.23284502
https://doi.org/10.1101/2023.01.20.23284502
Autor:
Takehiko Yokomizo, Yoko Ozawa, Ayana Suzumura, Toshiaki Hirakata, Hiroki Kaneko, Hideyuki Shimizu, Norie Nonobe, Seina Ito, Kazuhisa Yamada, Toshiaki Okuno, Yasuhito Funahashi, Fuxiang Ye, Masatoshi Nagaya, Keiko Kataoka, Kei Takayama, Rina Namba, Hiroko Terasaki
Publikováno v:
Diabetes. 69:724-735
Diabetic retinopathy (DR) is a widespread vision-threatening disease, and neuroretinal abnormality should be considered as an important problem. Brain-derived neurotrophic factor (BDNF) has recently been considered as a possible treatment to prevent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e46dc20b2412545a3142a976715e2604
https://doi.org/10.2337/db19-0550
https://doi.org/10.2337/db19-0550
Autor:
Keiko Kataoka, Hideyuki Shimizu, Kazuhisa Yamada, Ayana Suzumura, Hiroko Terasaki, Hiroki Kaneko, Masataka Sugimoto, Kei Takayama
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose To determine whether caveolin-1 (i) prevents epithelial-mesenchymal transition in the RPE and laser-induced subretinal fibrosis and (ii) promotes or inhibits cellular senescence in the RPE. Methods We examined laser-induced subretinal fibrosi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62b315ad60840939003d433bd94eb701
https://pubmed.ncbi.nlm.nih.gov/32926104
https://pubmed.ncbi.nlm.nih.gov/32926104
Autor:
Seina Ito, Ayana Suzumura, Kei Takayama, Hiroki Kaneko, Kazuhisa Yamada, Masataka Sugimoto, Hiroko Terasaki, Hideyuki Shimizu, Rina Namba
Publikováno v:
Translational Vision Science & Technology
Purpose Accumulation of the long noncoding Alu element RNA activates the NLRP3 inflammasome and leads to retinal pigment epithelium (RPE) cell death, a key event in the pathogenesis of geographic atrophy during late-stage age-related macular degenera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2896ca111074365649b3ef983003488
http://europepmc.org/articles/PMC7422901
http://europepmc.org/articles/PMC7422901