Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Kazuhisa Otake"'
Autor:
Makoto Sata, Yoko Shibata, Noriyuki Hirama, Jun-ichi Machiya, Isao Kubota, Noriaki Takabatake, Sumito Inoue, Toshihiro Wada, Kazuhisa Otake, Shuichi Abe
Publikováno v:
Respirology. 12:191-201
Background and objective: The molecular mechanisms underlying COPD remain undetermined. The lungs of surfactant protein-D (SP-D) deficient mice show emphysema and an excessive number of foamy macrophages. This study aims to elucidate roles of SP-D an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65cb9a853b5f54a646f2d13401555e04
https://doi.org/10.1111/j.1440-1843.2006.01009.x
https://doi.org/10.1111/j.1440-1843.2006.01009.x
Autor:
Isao Kubota, Toshihiro Wada, Kazuhisa Otake, Daisuke Osaka, Makoto Sata, Keiko Yamauchi, Shuichi Abe, Jun-ichi Machiya
Publikováno v:
Respirology. 8:532-535
Recently, propylthiouracil (PTU) has been thought to be one of the possible causes of antineutrophil cytoplasmic antibody (ANCA)-associated small vessel vasculitis syndrome, resulting in glomerulonephritis and, infrequently, diffuse alveolar haemorrh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b56747e58238a5581493bc84c78c803
https://doi.org/10.1046/j.1440-1843.2003.00499.x
https://doi.org/10.1046/j.1440-1843.2003.00499.x
Autor:
Jun Sato, Hiroaki Takeda, Kyoko Terashita, Hiroshi Saito, Hidenori Nakamura, Sumito Inoue, Kazuhisa Otake, Hitonobu Tomoike
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 167:764-770
Little is known about why patients with chronic obstructive pulmonary disease are susceptible to bacterial infections. Using an animal model of pulmonary emphysema, we investigated the inflammatory responses to bacterial infection. After intratrachea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::176285d9d8e7e8a3f3eb84244ebafa95
https://doi.org/10.1164/rccm.2105111
https://doi.org/10.1164/rccm.2105111
Publikováno v:
Blood. 98:2845-2852
Macrophage colony-stimulating factor (M-CSF) is one of several hematologic growth factors capable of regulating the survival, proliferation, and differentiation of macrophages, but its role in modulation of the accumulation and function of alveolar m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3f55a1f75003dc750fc945640f90b5c
https://doi.org/10.1182/blood.v98.9.2845
https://doi.org/10.1182/blood.v98.9.2845
Autor:
Fumio Sakane, Sachiko Saino-Saito, Yasukazu Hozumi, Kaoru Goto, Hisatake Kondo, Makoto Sata, Hideo Kanoh, Akira Suwabe, Yuji Katagiri, Isao Kubota, Tsukasa Ito, Kazuhisa Otake
Publikováno v:
American journal of physiology. Lung cellular and molecular physiology. 288(6)
Diacylglycerol kinase (DGK) catalyzes phosphorylation of diacylglycerol to generate phosphatidic acid, and both molecules are known to serve as second messengers as well as important intermediates for the synthesis of various lipids. In this study, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b5c34a8e6545e5c4780959f2b422f71
https://pubmed.ncbi.nlm.nih.gov/15734788
https://pubmed.ncbi.nlm.nih.gov/15734788
Autor:
Hidenori Nakamura, Sumito Inoue, Toshihiro Wada, Kazuhisa Otake, Noriaki Takabatake, Makoto Sata, Isao Kubota, Hitonobu Tomoike, Jun Sato
Publikováno v:
International journal of cancer. 106(6)
Thymidine phosphorylase (TP) is expressed at higher levels in a variety of human cancers than in adjacent normal tissue. It is reported that the higher expression is associated with an increase of intratumoral microvessel density and a poor prognosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc22543bd3590da3afba1606826859f0
https://pubmed.ncbi.nlm.nih.gov/12918063
https://pubmed.ncbi.nlm.nih.gov/12918063
Autor:
Pierre-Yves Berclaz, Yoko Shibata, Zsuzsanna K. Zsengellér, Steven Strasbaugh, Bruce C. Trapnell, Jeffrey A. Whitsett, Kazuhisa Otake
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 169(11)
GM-CSF gene-targeted (GM−/−) mice have impaired pulmonary clearance of bacterial and fungal pathogens by alveolar macrophages (AMs). Because AMs also clear adenovirus from the lung, the role of GM-CSF in endocytic internalization of adenovirus by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c266ed0e3a6fb3783d55d2f587c22db
https://pubmed.ncbi.nlm.nih.gov/12444140
https://pubmed.ncbi.nlm.nih.gov/12444140
Autor:
Shaikh-Abu Hossain, Kazuhisa Otake, Bruce C. Trapnell, Pierre-Yves Berclaz, Zsuzsanna K. Zsengellér
Publikováno v:
Journal of virology. 74(20)
Adenovirus is a common respiratory pathogen which causes a broad range of distinct clinical syndromes and has recently received attention for its potential for in vivo gene delivery. Although adenovirus respiratory tract infection (ARTI) results in d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96d7a3a165ab080bdad937695635dd9a
https://pubmed.ncbi.nlm.nih.gov/11000238
https://pubmed.ncbi.nlm.nih.gov/11000238
Publikováno v:
The American journal of physiology. 277(3)
Surfactant protein A (SP-A) is a member of the collectin family of host defense molecules expressed primarily in the epithelial cells of the lung. To determine the role of SP-A in pulmonary adenoviral infection, SP-A-deficient (SP-A -/-) mice were in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36964b183aec4c1de6bf3d573579850f
https://pubmed.ncbi.nlm.nih.gov/10484466
https://pubmed.ncbi.nlm.nih.gov/10484466
Autor:
Hitonobu Tomoike, Keiji Takahashi, Naoshi Yakuwa, Hiroki Suzuki, Yasushi Saito, Akira Suwabe, Miyuki Ito, Kazuhisa Otake
Publikováno v:
American journal of respiratory and critical care medicine. 158(6)
Neutrophils cause lung injuries by releasing proteases and active oxygen radicals in patients with acute respiratory distress syndrome (ARDS). Artificial surfactant is used to replace native surfactant whose functions are deteriorated by serum-derive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14cd2b810a3f211882047279c51c1ae0
https://pubmed.ncbi.nlm.nih.gov/9847283
https://pubmed.ncbi.nlm.nih.gov/9847283