Zobrazeno 1 - 10
of 290
pro vyhledávání: '"Kazuhisa Nakayama"'
Autor:
Asuka Hamamoto, Natsuki Kita, Siddabasave Gowda B. Gowda, Hiroyuki Takatsu, Kazuhisa Nakayama, Makoto Arita, Shu-Ping Hui, Hye-Won Shin
Publikováno v:
Cell Structure and Function, Vol 49, Iss 1, Pp 1-10 (2023)
Gaucher disease (GD) is a recessively inherited lysosomal storage disorder characterized by a deficiency of lysosomal glucocerebrosidase (GBA1). This deficiency results in the accumulation of its substrate, glucosylceramide (GlcCer), within lysosomes
Externí odkaz:
https://doaj.org/article/dac1dd9dc36f40f89f54c83bb79bee6d
Autor:
Takashi Uesugi, Yoshiaki Shimoo, Motohiro Munakata, Daisuke Sato, Kikue Yamaguchi, Michiya Fujimaki, Kazuhisa Nakayama, Tae Watanabe, Paulo Malo
Publikováno v:
International Journal of Implant Dentistry, Vol 9, Iss 1, Pp 1-17 (2023)
Abstract Purpose Implant-supported immediately loaded fixed full-arch rehabilitation via All-on-four treatment yields good long-term results for both the maxilla and the mandible. However, the risk factors affecting long-term implant survival are unk
Externí odkaz:
https://doaj.org/article/60745caef4e54b2997cfead96cce7ea4
Autor:
Natsuki Kita, Asuka Hamamoto, Siddabasave Gowda B. Gowda, Hiroyuki Takatsu, Kazuhisa Nakayama, Makoto Arita, Shu-Ping Hui, Hye-Won Shin
Publikováno v:
Journal of Lipid Research, Vol 65, Iss 3, Pp 100508- (2024)
Lipid transport is an essential cellular process with importance to human health, disease development, and therapeutic strategies. Type IV P-type ATPases (P4-ATPases) have been identified as membrane lipid flippases by utilizing nitrobenzoxadiazole (
Externí odkaz:
https://doaj.org/article/b37a55b4e42d4457a8be6c49887a8ab6
Autor:
Takashi Uesugi, Yoshiaki Shimoo, Motohiro Munakata, Yu Kataoka, Daisuke Sato, Kikue Yamaguchi, Minoru Sanda, Michiya Fujimaki, Kazuhisa Nakayama, Tae Watanabe, Paulo Malo
Publikováno v:
Bioengineering, Vol 11, Iss 3, p 223 (2024)
Early implant failure occurring within 1 year after implantation has been attributed to various factors. Particularly, early failure can lead to challenges in maintaining a full-arch prosthetic device, necessitating prompt intervention, including reo
Externí odkaz:
https://doaj.org/article/1cb0ec53598b401e8444eec537ee3a9c
Publikováno v:
Biology Open, Vol 12, Iss 7 (2023)
Externí odkaz:
https://doaj.org/article/9a0fea094add44608357dcef76821448
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Cilia play crucial roles in sensing and transducing extracellular signals. Bidirectional protein trafficking within cilia is mediated by the intraflagellar transport (IFT) machinery containing IFT-A and IFT-B complexes, with the aid of kines
Externí odkaz:
https://doaj.org/article/1a32ca68ec684dd1852dae7dc93a57e0
Publikováno v:
Biology Open, Vol 10, Iss 9 (2021)
INPP5E, a phosphoinositide 5-phosphatase, localizes on the ciliary membrane via its C-terminal prenyl moiety, and maintains the distinct ciliary phosphoinositide composition. The ARL3 GTPase contributes to the ciliary membrane localization of INPP5E
Externí odkaz:
https://doaj.org/article/5dc95fdd7b6d4a12a441bc7369127e03
Publikováno v:
Biology Open, Vol 10, Iss 1 (2021)
Compositions of proteins and lipids within cilia and on the ciliary membrane are maintained to be distinct from those of the cytoplasm and plasma membrane, respectively, by the presence of the ciliary gate. INPP5E is a phosphoinositide 5-phosphatase
Externí odkaz:
https://doaj.org/article/2c7c853c853c4ff7bd173fca789142f6
Publikováno v:
PLoS ONE, Vol 16, Iss 10, p e0258497 (2021)
CCRK/CDK20 was reported to interact with BROMI/TBC1D32 and regulate ciliary Hedgehog signaling. In various organisms, mutations in the orthologs of CCRK and those of the kinase ICK/CILK1, which is phosphorylated by CCRK, are known to result in cilia
Externí odkaz:
https://doaj.org/article/02f250ef848342c5a1a72fd5de9fce8f
Autor:
Hiroyuki Takatsu, Masahiro Takayama, Tomoki Naito, Naoto Takada, Kazuya Tsumagari, Yasushi Ishihama, Kazuhisa Nakayama, Hye-Won Shin
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
ATP11C is a flippase that uses ATP hydrolysis to translocate phospholipids at the plasma membrane. Here, the authors show that the activation of Ca2+-dependent protein kinase C increases ATP11C endocytosis thus downregulating phospholipid translocati
Externí odkaz:
https://doaj.org/article/1d7e2d5697f84925aba45325575c3bb5