Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Kazuhiro Yoshitani"'
Autor:
Yasuhito Tanaka, Manabu Akahane, Yumiko Kondo, Hiromasa Fujii, Motohiro Imano, Akira Kido, Kazuhiro Yoshitani, Takamasa Shimizu, Kanya Honoki, Shinji Tsukamoto
Publikováno v:
Oncology Letters. 4:745-750
The β2-adrenergic receptor (β2AR) mediates the effects of chronic stress in several neoplasms, however, β2AR signaling is impaired by hypoxia in various tissues. While hypoxia is a common feature significant in the progression of solid tumors, lit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57f288534934025e4ed4aad2aecac71e
https://doi.org/10.3892/ol.2012.813
https://doi.org/10.3892/ol.2012.813
Autor:
Akira Kido, Hiromasa Fujii, Manabu Akahane, Yasuhito Tanaka, Kazuhiro Yoshitani, Kanya Honoki
Publikováno v:
Pathology - Research and Practice. 207:417-422
Bisphosphonates (BPs) are agents used for treating disorders of excessive bone resorption. In addition, due to their cell-killing activity, BPs were potent candidates for adjuvant cancer therapy. On the other hand, low-concentrations of BPs have been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0cb9e0d13caf125bb6ea8c552f7cd85
https://doi.org/10.1016/j.prp.2011.04.007
https://doi.org/10.1016/j.prp.2011.04.007
Publikováno v:
Journal of Orthopaedic Science. 14:219-223
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::608bfd9d946eb43659cb37bc1957f973
https://doi.org/10.1007/s00776-008-1314-7
https://doi.org/10.1007/s00776-008-1314-7
Autor:
Kazuhiro Yoshitani, Hiromasa Fujii, Takeshi Morii, Akira Kido, Itsuto Amano, Haruyuki Tanaka, Kanya Honoki, Yasuhito Tanaka
Publikováno v:
Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association. 15(5)
Small round cell sarcomas (SRSs) comprise a heterogeneous group of malignant neoplasms with similar cytomorphology characterized by small, round, relatively undifferentiated cells; the group includes Ewing family sarcomas and rhabdomyosarcoma. These
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ee760a8592e2f82b3b0580d18d4e8fb
https://pubmed.ncbi.nlm.nih.gov/20953934
https://pubmed.ncbi.nlm.nih.gov/20953934
Autor:
Hiromasa, Fujii, Kanya, Honoki, Toshifumi, Tsujiuchi, Akira, Kido, Kazuhiro, Yoshitani, Yoshinori, Takakura
Publikováno v:
In vivo (Athens, Greece). 22(1)
2-Methoxyestradiol (2-ME) has been found to possess antitumor activity in vivo and in vitro. It has been suggested that 2-ME induces apoptosis resulting in G2/M arrest of tumor cells. In this study, the effect of 2-ME was evaluated in rat osteosarcom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dfbc8cc1e95a917b70d9b01d10c4ffa5
https://pubmed.ncbi.nlm.nih.gov/18396777
https://pubmed.ncbi.nlm.nih.gov/18396777
Autor:
Toshio Mori, Kanya Honoki, Toshifumi Tsujiuchi, Akira Kido, Kazuhiro Yoshitani, Hiromasa Fujii, Yoshinori Takakura
Publikováno v:
Biochemical and biophysical research communications. 362(3)
The presence of cancer stem cells, in both hematopoietic and solid malignancies, has been recently linked to their pathogenesis. We aimed to identify the characteristics and stem-like properties of sphere-colony forming cells in rat osteosarcoma and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4252ece1784093a8f727b916a18469c
https://pubmed.ncbi.nlm.nih.gov/17761140
https://pubmed.ncbi.nlm.nih.gov/17761140
Autor:
Toshio Mori, Kanya Honoki, Yoshio Mii, Yoshinori Takakura, Masahiro Tsutsumi, Toshifumi Tsujiuchi, Kazuhiro Yoshitani, Toru Morishita
Publikováno v:
Scopus-Elsevier
Flavopiridol is the potent inhibitor of cdks sharing its function with endogenous cdk inhibitors, and causes arrest at both the G1 and G2 phases of the cell cycle resulting in apoptosis in various tumor cell lines. Cyclin-dependent kinase inhibitor p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4236a58ef0f1d30eb713778f85584a72
https://pubmed.ncbi.nlm.nih.gov/15069542
https://pubmed.ncbi.nlm.nih.gov/15069542
Autor:
Masahiro Tsutsumi, Yoshio Mii, Kazuhiro Yoshitani, Toshio Mori, Toshifumi Tsujiuchi, Kanya Honoki, Yoshinori Takakura
Publikováno v:
Molecular carcinogenesis. 39(1)
Loss of p16 I N K 4 a protein expression has frequently been related to DNA methylation in association with gene silencing. Although the methylation status of exon1α for p16 I N K 4 a involvement in various cancers has been extensively analyzed, it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a9b8ee4b77d16dfa2b7a93e0ddfc4ba
https://pubmed.ncbi.nlm.nih.gov/14694443
https://pubmed.ncbi.nlm.nih.gov/14694443
Autor:
Kazuhiro, Yoshitani, Kanya, Honoki, Toru, Morishita, Akira, Kido, Yoshizumi, Miyauchi, Yoshio, Mii, Yoshinori, Takakura
Publikováno v:
In vivo (Athens, Greece). 17(3)
STI571 is a 2-phenylaminopyrimide derivative that was designed as an Abl tyrosine kinase inhibitor, but it is also effective against platelet-derived growth factor receptor (PDGFR) and c-Kit tyrosine kinase. Recent studies have demonstrated that STI5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2003a46fdf4b66453ef913483fc255cf
https://pubmed.ncbi.nlm.nih.gov/12929576
https://pubmed.ncbi.nlm.nih.gov/12929576
Publikováno v:
Journal of Orthopaedic Science. Mar2009, Vol. 14 Issue 2, p219-223. 5p.