Zobrazeno 1 - 10
of 383
pro vyhledávání: '"Kazuhiro Yoshikawa"'
Publikováno v:
Nihon Kikai Gakkai ronbunshu, Vol 89, Iss 926, Pp 23-00112-23-00112 (2023)
The axle spring vibration isolator rubber installed on the axle box that encloses the axle bearings is subjected to loads corresponding to the wheel weight and vibration of the axle box during running. It is thought that the running condition of the
Externí odkaz:
https://doaj.org/article/9c86053d67ee473782b9117cfe8820e0
Autor:
Shoya Ono, Susumu Suzuki, Yutaro Kondo, Ikuko Okubo, Mitsuo Goto, Tetsuya Ogawa, Hidefumi Kato, Hideaki Ito, Taishi Takahara, Akira Satou, Toyonori Tsuzuki, Kazuhiro Yoshikawa, Toru Nagao, Ryuzo Ueda
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Regulatory T-cells (Tregs) play a major role in suppressing anti-tumor immune responses. Mogamulizumab, an anti-CC chemokine receptor type 4 (CCR4) monoclonal antibody, depletes effector Tregs (eTregs). However, the clinical efficacy of moga
Externí odkaz:
https://doaj.org/article/47020566b5224fc5b119f9be4216c769
Autor:
Yawara Kikuchi, Yoshimi Odashima, Kazuhiro Yoshikawa, Tomoyasu Oda, Fumitaka Tanaka, Hiroki Oikawa, Yasushi Ishigaki, Koichi Asahi
Publikováno v:
BMC Nephrology, Vol 23, Iss 1, Pp 1-6 (2022)
Abstract Background Vascular endothelial growth factor inhibitors (VEGFIs) are used to treat malignant neoplasms and ocular diseases by inhibiting angiogenesis. Systemic use of VEGFIs has various side effects, including hypertension, proteinuria, and
Externí odkaz:
https://doaj.org/article/9ef4fbd330c74e0b8b9186ef124a6752
Autor:
Takahiro Oike, Naoto Osu, Yuya Yoshimoto, Hideru Obinata, Kazuhiro Yoshikawa, Curtis C. Harris, Tatsuya Ohno
Publikováno v:
Heliyon, Vol 9, Iss 6, Pp e16684- (2023)
This pilot study aimed primarily to evaluate plasma levels of a novel metabolite, creatine riboside, in patients with cervical cancer (discovery and validation cohorts, n = 11 for each) compared with non-cancer subjects (controls, n = 30). We found t
Externí odkaz:
https://doaj.org/article/411de5e1572c4040a062bc901d1a6104
Tumor‐infiltrating FoxP3+ T cells are associated with poor prognosis in oral squamous cell carcinoma
Autor:
Tomio Hayashi, Kazuhiro Yoshikawa, Susumu Suzuki, Masahiko Gosho, Ryuzo Ueda, Yoshiaki Kazaoka
Publikováno v:
Clinical and Experimental Dental Research, Vol 8, Iss 1, Pp 152-159 (2022)
Abstract Objectives Squamous cell carcinoma is the most common malignancy in the oral cavity. Moreover, human papillomavirus (HPV) infection has been recently implicated in the onset of oral squamous cell carcinoma (OSCC). Regulatory T cells (Tregs)
Externí odkaz:
https://doaj.org/article/cc7e8b6bd18842ffa577560e42444a7a
Autor:
Ichiro Hanamura, Susumu Suzuki, Akinobu Ota, Satsuki Murakami, Akira Satou, Taishi Takahara, Sivasundaram Karnan, Vu Quang Lam, Ayano Nakamura, Souichi Takasugi, Kazuhiro Yoshikawa, Shogo Banno, Masayuki Ejiri, Toyonori Tsuzuki, Yoshitaka Hosokawa, Ryuzo Ueda, Akiyoshi Takami
Publikováno v:
Hemato, Vol 2, Iss 2, Pp 368-382 (2021)
The clinical and biological significance of programmed death-1 (PD-1) expression by B-lymphoma cells is largely unknown. Here, using multicolor immunofluorescent staining (MC-IF), we investigated PD-1 and PD-L1 expression in PAX5+ (B-lymphoma), CD68+
Externí odkaz:
https://doaj.org/article/aa32f8c19b92443e840c847084530e68
Autor:
Sivasundaram Karnan, Ichiro Hanamura, Akinobu Ota, Souichi Takasugi, Ayano Nakamura, Miyuki Takahashi, Kaori Uchino, Satsuki Murakami, Md Wahiduzzaman, Lam Quang Vu, Md Lutfur Rahman, Muhammad Nazmul Hasan, Toshinori Hyodo, Hiroyuki Konishi, Shinobu Tsuzuki, Kazuhiro Yoshikawa, Susumu Suzuki, Ryuzo Ueda, Masayuki Ejiri, Yoshitaka Hosokawa, Akiyoshi Takami
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-14 (2021)
Abstract Internal tandem duplication (ITD) of FMS-like tyrosine kinase 3 (FLT3) confers poor prognosis and is found in approximately 25% of cases of acute myeloid leukemia (AML). Although FLT3 inhibitors have shown clinical benefit in patients with A
Externí odkaz:
https://doaj.org/article/eae8b2e7377a4befa2da2790f20890c7
Autor:
Izaya Nakaya, Taijiro Goto, Yuki Nakamura, Kazuhiro Yoshikawa, Junji Oyama, Yoshihiko Tamayama, Mizuho Morooka, Sadatoshi Ito, Hirotaka Ishioka, Yuki Matsuura, Jun Soma
Publikováno v:
Renal Replacement Therapy, Vol 7, Iss 1, Pp 1-9 (2021)
Abstract Background Creating permanent vascular access (VA) is recommended before hemodialysis initiation in patients with end-stage renal disease (ESRD). Although many patients are still introduced to hemodialysis with temporary central venous cathe
Externí odkaz:
https://doaj.org/article/6b4b9de813ec400190a10ff70fe7af15
Autor:
Shunpei Yamanaka, Susumu Suzuki, Hideaki Ito, Karnan Sivasundaram, Ichiro Hanamura, Ikuko Okubo, Kazuhiro Yoshikawa, Shoya Ono, Taishi Takahara, Akira Satou, Toyonori Tsuzuki, Ryuzo Ueda, Tetsuya Ogawa, Yasushi Fujimoto
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 2, p 1722 (2023)
Patients with advanced/recurrent mucoepidermoid carcinoma (MEC) have a poor prognosis. This study aimed to establish and characterize human mucoepidermoid carcinoma cell lines from the initial surgical specimen and biopsy specimen upon recurrence fro
Externí odkaz:
https://doaj.org/article/78971fc9ff01429fb56b391d4ba267d3
Autor:
Yawara Kikuchi, Yoshimi Odashima, Kazuhiro Yoshikawa, Tomoyasu Oda, Fumitaka Tanaka, Hiroki Oikawa, Yasushi Ishigaki, Koichi Asahi
Publikováno v:
BMC Nephrology, Vol 23, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/1ad32cc863694535ad113891c52832ed