Zobrazeno 1 - 10
of 221 874
pro vyhledávání: '"Kazuhiro So"'
Autor:
Noriyuki Tashima, Hisako Matsumoto, Kenta Nishi, Satoru Terada, Mariko Kogo, Natsuko Nomura, Chie Morimoto, Hironobu Sunadome, Tadao Nagasaki, Tsuyoshi Oguma, Yoshinari Nakatsuka, Kimihiko Murase, Takahisa Kawaguchi, Yasuharu Tabara, Kazuo Chin, Kazuhiro Sonomura, Fumihiko Matsuda, Toyohiro Hirai
Publikováno v:
Allergology International, Vol 73, Iss 1, Pp 65-70 (2024)
Background: Obesity and increased body mass index (BMI) are the known risk factors for adult-onset asthma. Serum free fatty acid (FFA) and other blood lipid levels are generally elevated in patients with obesity and may be involved in the onset of as
Externí odkaz:
https://doaj.org/article/c9c7048b066146c0b96b2dbcafab32b6
Autor:
Huiting Ou, Shuji Kawaguchi, Kazuhiro Sonomura, Takahisa Kawaguchi, Seri Kitada, Satoshi Yoshiji, François Brial, Dominique Gauguier, Jianguo Xia, Fumihiko Matsuda
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Gut-microbiota derived metabolites are important regulators of host biology and metabolism. To understand the impacts of the microbial metabolite 4-cresol sulfate (4-CS) on four chronic diseases [type 2 diabetes mellitus, metabolic syndrome
Externí odkaz:
https://doaj.org/article/4afe2ec4a5a647b29e0a385de7c55238
Autor:
Satoru Terada, Hisako Matsumoto, Kenta Nishi, Mariko Kogo, Natsuko Nomura, Noriyuki Tashima, Chie Morimoto, Hironobu Sunadome, Tadao Nagasaki, Tsuyoshi Oguma, Yoshinari Nakatsuka, Kimihiko Murase, Takahisa Kawaguchi, Yasuharu Tabara, Kazuhiro Sonomura, Fumihiko Matsuda, Kazuo Chin, Toyohiro Hirai
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Little is known about the association of prolonged cough, a common and troublesome symptom, with metabolic pathways. We aimed to clarify this association using data from the Nagahama cohort, a prospective study of participants from the gener
Externí odkaz:
https://doaj.org/article/d1bd0f2937bb491ea83cee5acbcf050d
Autor:
Yoshinari Nakatsuka, Kimihiko Murase, Kazuhiro Sonomura, Yasuharu Tabara, Tadao Nagasaki, Satoshi Hamada, Takeshi Matsumoto, Takuma Minami, Osamu Kanai, Hirofumi Takeyama, Hironobu Sunadome, Naomi Takahashi, Isuzu Nakamoto, Kiminobu Tanizawa, Tomohiro Handa, Taka-Aki Sato, Naoko Komenami, Tomoko Wakamura, Satoshi Morita, Osamu Takeuchi, Takeo Nakayama, Toyohiro Hirai, Yoichiro Kamatani, Fumihiko Matsuda, Kazuo Chin
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Sleep disordered breathing (SDB), mainly obstructive sleep apnea (OSA), constitutes a major health problem due to the large number of patients. Intermittent hypoxia caused by SDB induces alterations in metabolic function. Nevertheless, metab
Externí odkaz:
https://doaj.org/article/995332e3dbfc42f6bfcf3b59d82dd244
Autor:
Yutaro Ohno, Eri Okita, Mika Kawai-Uchida, Youji Shoukei, Kazuhiro Soshiroda, Tomoyuki Kanda, Shinichi Uchida
Publikováno v:
Journal of Pharmacological Sciences, Vol 152, Iss 3, Pp 193-199 (2023)
The adenosine A2A receptor antagonist/inverse agonist, KW-6356 has been shown to be effective in Parkinson's disease (PD) patients as monotherapy and as an adjunct therapy to L-3,4-dihydroxyphenylalanine (L-DOPA)/decarboxylase inhibitor. However, the
Externí odkaz:
https://doaj.org/article/c813e07e2733429a92c3bfbdfcba0ff4
Autor:
Morio Ueno, MD, PhD, Kengo Yoshii, PhD, Tomoko Yamashita, PhD, Kazuhiro Sonomura, PhD, Kazuko Asada, BEng, Eiko Ito, BSci, Tomoko Fujita, BEd, Chie Sotozono, MD, PhD, Shigeru Kinoshita, MD, PhD, Junji Hamuro, PhD
Publikováno v:
Ophthalmology Science, Vol 3, Iss 3, Pp 100299- (2023)
Purpose: The purpose of the study was to clarify the interplay between metabolites and microRNAs (miRs) in the aqueous humor (AqH) of bullous keratopathy (BK) patients to retain human corneal endothelium (HCE) integrity. Design: Prospective, comparat
Externí odkaz:
https://doaj.org/article/cabf9c0d46004751afc2079ae9d7e9ea
Autor:
Kimiyuki Asano, Tomotaka Iwata, Kunikazu Yoshida, Naoto Inoue, Kazuhiro Somei, Ken Miyakoshi, Michihiro Ohori
Publikováno v:
Earth, Planets and Space, Vol 74, Iss 1, Pp 1-25 (2022)
Abstract The Hakodate Plain in the southern part of the Oshima Peninsula, Hokkaido, Japan, is a sedimentary basin surrounded by mountains. The vertical displacements caused by active faults along the western margin of the Hakodate Plain increased the
Externí odkaz:
https://doaj.org/article/81c4aad67c7546ebadc1019eaaa63041
Publikováno v:
Earth, Planets and Space, Vol 74, Iss 1, Pp 1-15 (2022)
Abstract Ground motions near the source area of the mainshock of the 2013 Lushan earthquake (M w 6.6) in Sichuan Province in China were reproduced using the characterized source model and the empirical Green’s function method (EGFM). The best-fit c
Externí odkaz:
https://doaj.org/article/194a8ea3e355463282759e7035b00fd6
Autor:
Takeshi Iwasaki, Yoichiro Kamatani, Kazuhiro Sonomura, Shuji Kawaguchi, Takahisa Kawaguchi, Meiko Takahashi, Koichiro Ohmura, Taka-Aki Sato, Fumihiko Matsuda
Publikováno v:
iScience, Vol 26, Iss 1, Pp 105738- (2023)
Summary: An increase in ethnic diversity in genetic studies has the potential to provide unprecedented insights into how genetic variations influence human phenotypes. In this study, we conducted a quantitative trait locus (QTL) analysis of 121 metab
Externí odkaz:
https://doaj.org/article/8c693a9441bf47989f2c23676755dc2a
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-10 (2021)
Abstract Inhibitory PAS domain protein (IPAS) is a bifunctional protein that acts as a transcriptional repressor in hypoxia and as a pro-apoptotic protein involved in neuronal cell death. Npas4 (NXF or LE-PAS) is a transcriptional factor that protect
Externí odkaz:
https://doaj.org/article/6a238c8df7834ef9b7d3048d59d886ba