Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Kazuhiro Onuma"'
Autor:
Takushi Kawamorita, Hiroshi Uozato, Tetsuro Oshika, Kazuno Negishi, Takashi Fujikado, Akira Murakami, Kazutaka Kamiya, Naoyuki Maeda, Yuta Ueno, Kazuhiro Onuma, Masakazu Hirota, Rie Hoshikawa, Sachiko Masui, Masahiro Yamaguchi, Toshifumi Mihashi
Publikováno v:
PLoS ONE, Vol 17, Iss 7 (2022)
This prospective observational study aimed to evaluate the ocular biometry of Japanese people through a multicenter approach. The uncorrected and corrected distance visual acuity (UDVA and CDVA, respectively) in the log minimum angle of resolution (l
Externí odkaz:
https://doaj.org/article/0f3d81f6f17a44e7bbb3ae458eacf270
Autor:
Tue W. Kragstrup, Dong H. Sohn, Christin M. Lepus, Kazuhiro Onuma, Qian Wang, William H. Robinson, Jeremy Sokolove
Publikováno v:
BMC Rheumatology, Vol 3, Iss 1, Pp 1-8 (2019)
Abstract Background The pathophysiology of osteoarthritis (OA) involves wear and tear, and a state of low-grade inflammation. Tissue repair responses include transforming growth factor beta (TGFβ)-induced myofibroblast production of extracellular ma
Externí odkaz:
https://doaj.org/article/a50a41d9eb314ea48a725fd4f7b270d3
Autor:
Risako Kon, Nobutomo Ikarashi, Kazuhiro Onuma, Zenta Yasukawa, Makoto Ozeki, Hiroyasu Sakai, Junzo Kamei
Publikováno v:
Food Science & Nutrition. 11:1127-1133
In recent years, the development of functional foods targeting gastrointestinal disorders has been in progress. Partially hydrolyzed guar gum (PHGG), which is a water-soluble dietary fiber, is known to have a constipation-improving effect. However, m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1b0893be93770296ff401606d4fa974
https://doi.org/10.1002/fsn3.3150
https://doi.org/10.1002/fsn3.3150
Autor:
Risako Kon, Nobutomo Ikarashi, Kazuhiro Onuma, Zenta Yasukawa, Makoto Ozeki, Hiroyasu Sakai, Junzo Kamei
Publikováno v:
Food Sci Nutr
The cover image is based on the Original Article Effect of partially hydrolyzed guar gum on the expression of aquaporin‐3 in the colon by Risako Kon et al., https://doi.org/10.1002/fsn3.3150 [Image: see text]
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8f43516951af86da883f767c4c5c2ea
https://doi.org/10.1002/fsn3.3264
https://doi.org/10.1002/fsn3.3264
Publikováno v:
Nephrology Dialysis Transplantation. 37
BACKGROUND AND AIMS Bardoxolone methyl is a covalent Kelch-like ECH-associated protein 1 (Keap1) inhibitor that induces nuclear factor erythroid 2-related factor 2 (Nrf2) activation. Bardoxolone methyl improved glomerular filtration rate (GFR) in cli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd4fe471d2388527e339d9a449718776
https://doi.org/10.1093/ndt/gfac074.023
https://doi.org/10.1093/ndt/gfac074.023
Autor:
Toshifumi Mihashi, Kazuno Negishi, Kazuhiro Onuma, Masakazu Hirota, Takushi Kawamorita, Takashi Fujikado, Tetsuro Oshika, Rie Hoshikawa, Hiroshi Uozato, Kazutaka Kamiya, Naoyuki Maeda, Sachiko Masui, Masahiro Yamaguchi, Yuta Ueno, Akira Murakami
This prospective observational study aimed to evaluate the eye shape and visual function of Japanese people through a multicenter approach and to create a Japanese model eye. Uncorrected and corrected distance visual acuity (UDVA and CDVA, respective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55305a3d123bd91c7e318c556f44c89b
https://doi.org/10.21203/rs.3.rs-988545/v1
https://doi.org/10.21203/rs.3.rs-988545/v1
Autor:
Shota Kaseda, Yuya Sannomiya, Jun Horizono, Jun Kuwazuru, Mary Ann Suico, Sayaka Ogi, Ryoko Sasaki, Hidetoshi Sunamoto, Hirohiko Fukiya, Hayato Nishiyama, Misato Kamura, Saki Niinou, Yuimi Koyama, Futoshi Nara, Tsuyoshi Shuto, Kazuhiro Onuma, Hirofumi Kai
Publikováno v:
Kidney360
BACKGROUND: Bardoxolone methyl activates nuclear factor erythroid 2–related factor 2 (Nrf2) via covalent binding and irreversible inhibition of Kelch-like ECH-associated protein 1 (Keap1), the negative regulator of Nrf2. Ongoing clinical trials of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e3d502c89ec9099fd5c10558fc0c7bb
https://pubmed.ncbi.nlm.nih.gov/35721612
https://pubmed.ncbi.nlm.nih.gov/35721612
Autor:
Shota Kaseda, Yuya Sannomiya, Jun Horizono, Jun Kuwazuru, Mary Ann Suico, Sayaka Ogi, Ryoko Sasaki, Hidetoshi Sunamoto, Hirohiko Fukiya, Hayato Nishiyama, Misato Kamura, Futoshi Nara, Tsuyoshi Shuto, Kazuhiro Onuma, Hirofumi Kai
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. 95:1-YIA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f122231a086e048a53c0f321abe7c2e
https://doi.org/10.1254/jpssuppl.95.0_1-yia-22
https://doi.org/10.1254/jpssuppl.95.0_1-yia-22
Autor:
Eileen E Elliott, Michelle S. Bloom, Kazuhiro Onuma, Zhen Cheng, Christin M. Lepus, Nick Hu, Harini Raghu, Changhao Liu, Heidi Wong, Cecilia Cisar, Qian Wang, Nicholas J. Giori, Dong Hyun Sohn, Stephen B. Willingham, Irving L. Weissman, Rong Mao, Orr Sharpe, Susan S. Prohaska, Richard R.L. Cao, Xiaoyan Zhao, Constance R. Chu, Nithya Lingampalli, Jeremy Sokolove, William H. Robinson
Osteoarthritis (OA) is the leading cause of joint failure, yet the underlying mechanisms remain elusive, and no approved therapies that slow progression exist. Dysregulated integrin function was previously implicated in OA pathogenesis. However, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bc7310c7d3d6d12f37f283915636741
https://europepmc.org/articles/PMC6795293/
https://europepmc.org/articles/PMC6795293/
Autor:
Kazuhiro Onuma, Qian Wang, Christin M. Lepus, Dong H. Sohn, Jeremy Sokolove, William H. Robinson, Tue Wenzel Kragstrup
Publikováno v:
Kragstrup, T W, Sohn, D H, Lepus, C M, Onuma, K, Wang, Q, Robinson, W H & Sokolove, J 2019, ' Fibroblast-like synovial cell production of extra domain A fibronectin associates with inflammation in osteoarthritis ', BMC Rheumatology, vol. 3, 46 . https://doi.org/10.1186/s41927-019-0093-4
BMC Rheumatology
BMC Rheumatology, Vol 3, Iss 1, Pp 1-8 (2019)
BMC Rheumatology
BMC Rheumatology, Vol 3, Iss 1, Pp 1-8 (2019)
Background The pathophysiology of osteoarthritis (OA) involves wear and tear, and a state of low-grade inflammation. Tissue repair responses include transforming growth factor beta (TGFβ)-induced myofibroblast production of extracellular matrix. Fib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e27df9ed73aeaac7e0ac9e0df06fec08
https://pure.au.dk/portal/da/publications/fibroblastlike-synovial-cell-production-of-extra-domain-a-fibronectin-associates-with-inflammation-in-osteoarthritis(4ed6fba2-b9bd-462b-9a92-1b0aff266dbc).html
https://pure.au.dk/portal/da/publications/fibroblastlike-synovial-cell-production-of-extra-domain-a-fibronectin-associates-with-inflammation-in-osteoarthritis(4ed6fba2-b9bd-462b-9a92-1b0aff266dbc).html