Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Kazuhiro Kitada"'
A mutation in the gene encoding mitochondrial Mg²+ channel MRS2 results in demyelination in the rat.
Autor:
Takashi Kuramoto, Mitsuru Kuwamura, Satoko Tokuda, Takeshi Izawa, Yoshifumi Nakane, Kazuhiro Kitada, Masaharu Akao, Jean-Louis Guénet, Tadao Serikawa
Publikováno v:
PLoS Genetics, Vol 7, Iss 1, p e1001262 (2011)
The rat demyelination (dmy) mutation serves as a unique model system to investigate the maintenance of myelin, because it provokes severe myelin breakdown in the central nervous system (CNS) after normal postnatal completion of myelination. Here, we
Externí odkaz:
https://doaj.org/article/32f36d506792456791f4c80dbbe0fd47
Autor:
Shota Murakami, Kimiyuki Tsuchiya, Keisuke Nakata, Mana Nishikata, Kazuhiro Kitada, Hitoshi Suzuki
Publikováno v:
Mammal Study. 47
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb9fe2243ddd9cb2b3df6336245ff9f0
https://doi.org/10.3106/ms2022-0003
https://doi.org/10.3106/ms2022-0003
Autor:
Minako Yoshihara, Takashi Kuramoto, S Nakanishi, Kazuhiro Kitada, Masashi Sasa, Mikita Suyama, Tadao Serikawa, Mitsuru Kuwamura, Tadashi Nakamura, Saki Shimizu, Birger Voigt, Kaori Wakamatsu, Miyuu Tanaka, Risa Uemura, Yukihiro Ohno
Publikováno v:
Behavior Genetics. 47:609-619
The Noda epileptic rat (NER) exhibits generalized tonic-clonic seizures (GTCS). A genetic linkage analysis identified two GTCS-associated loci, Ner1 on Chr 1 and Ner3 on Chr 5. The wild-type Ner1 and Ner3 alleles suppressed GTCS when combined in doub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::902f60b0bdad1ba54a1dc735e9b822f4
https://doi.org/10.1007/s10519-017-9870-2
https://doi.org/10.1007/s10519-017-9870-2
Autor:
Mana Nishikata, Asato Kuroiwa, Shusei Mizushima, Takamichi Jogahara, Kazuhiro Kitada, Yuka Ogata
Publikováno v:
Developmental dynamics : an official publication of the American Association of AnatomistsREFERENCES. 248(9)
Background Although Tokudaia muenninki has multiple extra copies of the Sry gene on the Y chromosome, loss of function of these sequences is indicated. To examine the Sry gene function for sex determining in T. muenninki, we screened a BAC library an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da80a47625ab281f019172bd58ce121b
https://pubmed.ncbi.nlm.nih.gov/31219647
https://pubmed.ncbi.nlm.nih.gov/31219647
Autor:
Kensuke Sasaki, Yasufumi Hayano, Makoto Takemoto, Nami Ohmura, Nobuhiko Yamamoto, Yurie Maeda, Yoshio Hata, Toshihide Yamashita, Kazuhiro Kitada
Publikováno v:
Proceedings of the National Academy of Sciences. 111:15226-15231
Axon branching is remodeled by sensory-evoked and spontaneous neuronal activity. However, the underlying molecular mechanism is largely unknown. Here, we demonstrate that the netrin family member netrin-4 (NTN4) contributes to activity-dependent thal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9a2f81d993664057c80d2261e5b1f55
https://doi.org/10.1073/pnas.1402095111
https://doi.org/10.1073/pnas.1402095111
Publikováno v:
Experimental Animals. 62:219-227
The tremor rat is an autosomal recessive mutant exhibiting sterility with gonadal hypoplasia in both sexes. The causative mutation tremor (tm) is known as a genomic deletion spanning >200 kb in Chr 10q24. Spermatogenesis associated 22 (Spata22) has b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::804f92b0c96d9ec9b289dd52ab737936
https://doi.org/10.1538/expanim.62.219
https://doi.org/10.1538/expanim.62.219
Autor:
Yoshihisa Koyama, Yasufumi Hayano, Kazuhisa Minami, Koichi Ogawa, Keiko Takasu, Satoshi Kuwabara, Moe Yamada, Kazuhiro Kitada, Toshiyuki Asaki, Toshihide Yamashita
Publikováno v:
The Journal of Experimental Medicine
Hayano et al. show that Netrin-4, which is originally identified as an axon guidance molecule, is capable of enhancing sensitivity to sensory input and can contribute to neuropathic pain. The findings provide evidence for a previously unknown pain-in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdb38c17d93ce5db3f7fd081cb6ec8c4
https://pubmed.ncbi.nlm.nih.gov/27856613
https://pubmed.ncbi.nlm.nih.gov/27856613
Publikováno v:
Journal of Tissue Engineering and Regenerative Medicine. 9:375-388
Expanding undifferentiated induced pluripotent stem (iPS) cells in vitro is a basic requirement for application of iPS cells in both fundamental research and clinical regeneration. In this study, we intended to establish a simple, low cost and effici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b73a6c37a3eb020ff063bc3a125c1627
https://doi.org/10.1002/term.1640
https://doi.org/10.1002/term.1640
Autor:
Takashi Kuramoto, Masaharu Akao, Noriaki Tanimoto, S Nakanishi, Masashi Sasa, Toru Kita, Mitsuru Kuwamura, Hiroshi Gohma, Takeru Makiyama, Kazuhiro Kitada, Tadao Serikawa, Ken-ichi Yamasaki, Ryoko Okajima
Publikováno v:
Physiological Genomics. 24:198-206
KCNQ1 forms K+channels by assembly with regulatory subunit KCNE proteins and plays a key role in the K+homeostasis in a variety of tissues. In the heart, KCNQ1 is coassembled with KCNE1 to produce a cardiac delayed rectifier K+current. In the inner e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eb674ec6bd5cf6d0166fedf30e6db48
https://doi.org/10.1152/physiolgenomics.00221.2005
https://doi.org/10.1152/physiolgenomics.00221.2005
Autor:
Yosuke Ando, Jyoji Yamate, Mitsuru Kuwamura, Kazuhiro Kitada, Shigehito Takeshita, Tadao Serikawa, Toshiko Kanehara, Akiko Takada, Miyuki Kanbori, Takao Kotani
Publikováno v:
Experimental Animals. 53:21-26
In this paper, we executed genome mapping and comparative mapping analyses for cvd and hob, autosomal recessive mutations with cerebellar vermis defect and cerebellar dysplasia in the rat. For the linkage analysis, we produced three sets of backcross
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a71b4f7a6d115ddc0f9dae59cacb9989
https://doi.org/10.1538/expanim.53.21
https://doi.org/10.1538/expanim.53.21