Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Kazuhiro Nagaike"'
Autor:
Haruyasu Yamaguchi, Mako Takami, Shigeo Murayama, Yasuhiro Hashimoto, Nobuto Kakuda, Hiroyuki Arai, Yasuo Ihara, Hajime Arai, Takeshi Ikeuchi, Kohei Akazawa, Mikio Shoji, Hiroyuki Hatsuta, Kazuhiro Nagaike, Masakazu Miyajima, Yu Nagashima, Ryozo Kuwano, Katsutoshi Furukawa
Publikováno v:
EMBO Molecular Medicine
We investigated why the cerebrospinal fluid (CSF) concentrations of Aβ42 are lower in mild cognitive impairment (MCI) and Alzheimer's disease (AD) patients. Because Aβ38/42 and Aβ40/43 are distinct product/precursor pairs, these four species in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab682143a6b258f9b0133902670598f6
http://europepmc.org/articles/PMC3376855
http://europepmc.org/articles/PMC3376855
Autor:
Yasuko Mori, Pranee Somboonthum, Kazuhiro Nagaike, Takayoshi Imazawa, Hironori Yoshii, Koichi Yamanishi, Yoshiaki Yamagishi, Keiichi Ozono, Tomohiko Sadaoka
Publikováno v:
Journal of Virology. 82:795-804
Although envelope glycoprotein M (gM) is highly conserved among herpesviruses, the varicella-zoster virus (VZV) gM homolog has never been investigated. Here we characterized the VZV gM homolog and analyzed its function in VZV-infected cells. The VZV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87de6d05cdc02ac13156710943b2cfb0
https://doi.org/10.1128/jvi.01722-07
https://doi.org/10.1128/jvi.01722-07
Publikováno v:
The Prostate. 66:447-452
BACKGROUND Hepatocyte growth factor activator inhibitor type 1 (HAI-1) and type 2 (HAI-2) are Kunitz-type serine protease inhibitors for hepatocyte growth factor activator (HGFA). We attempted to clarify whether serum levels of HAI-1 and HAI-2 could
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58dbbc2ad0216b90ad6e51e67482dbd7
https://doi.org/10.1002/pros.20301
https://doi.org/10.1002/pros.20301
Autor:
Ulrich H. Koszinowski, Yasuyuki Gomi, Kazuhiro Nagaike, Michiaki Takahashi, Koichi Yamanishi, Hironori Yoshii, Markus Wagner, Yasuko Mori
Publikováno v:
Vaccine. 22:4069-4074
The complete genome of the varicella-zoster virus (VZV) Oka strain has been cloned as a bacterial artificial chromosome (BAC). Following electroporation into Escherichia coli (E. coli) strain DH10B, the VZV BAC was stably propagated over multiple gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b86b6fc6bbc35a186e3e94cb9af4aa6
https://doi.org/10.1016/j.vaccine.2004.03.062
https://doi.org/10.1016/j.vaccine.2004.03.062
Autor:
Toshiaki Tagawa, Yoko Hirakawa, Kazuhiro Nagaike, Katsuhiko Nohga, Saiko Hosokawa, Hisae Niki, Norihiko Ito
Publikováno v:
Hybridoma and Hybridomics. 23:109-120
To establish human monoclonal antibodies suitable for targeting chemotherapy, we prepared a panel of human-mouse hybridomas, using mouse myelomas and lymphocytes of regional lymph nodes excised from cancer patients, and selected antibodies on the bas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea4ac268161db0b47d95897a0a612511
https://doi.org/10.1089/153685904774129711
https://doi.org/10.1089/153685904774129711
Autor:
Ken Tsutsui, Satoshi Suzuki, Eiji Takayama, Takushi Tadakuma, Sadayuki Hiroi, Michito Kunitomi, Kazuhiro Nagaike, Tatsuji Yasuda
Publikováno v:
Japanese Journal of Cancer Research : Gann
We constructed a plasmid containing human alpha-fetoprotein (AFP) promoter/enhancer to direct the cell type-specific expression of diphtheria toxin fragment A (DTA), designated as pAF-DTA, to AFP-producing hepatocellular carcinoma cells. The transfec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6595586506e04f0c5aa2e16953729797
https://doi.org/10.1111/j.1349-7006.2000.tb00951.x
https://doi.org/10.1111/j.1349-7006.2000.tb00951.x
Publikováno v:
FEBS Letters. 413:177-180
We have developed a new type of long-circulating immunoliposome (Fab′–PEG immunoliposomes) which is efficiently extravasated into the targeted solid tumor in vivo. Small unilamellar liposomes (100–130 nm in diameter) were prepared from distearo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54f4d6898bf79e27fb374c499187ccd4
https://doi.org/10.1016/s0014-5793(97)00905-8
https://doi.org/10.1016/s0014-5793(97)00905-8
Autor:
Tomoko Takizawa, Toshiaki Tagawa, Nobuya Takahashi, Motoharu Iwatsuru, Kazuo Maruyama, Kazuhiro Nagaike
Publikováno v:
Advanced Drug Delivery Reviews. 24:235-242
We have developed a new type of PEG-immunoliposome carrying monoclonal antibodies or their fragments (F(ab′)2, Fab′) at the distal ends of the PEG chains (Type C). Distearoylphosphatidylethanolamine derivatives of PEG with car☐yl group (DSPE-PE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7a2320a1655fba5b92e580e98ba0e3c
https://doi.org/10.1016/s0169-409x(96)00463-2
https://doi.org/10.1016/s0169-409x(96)00463-2
Publikováno v:
Oncology. 50:35-40
We studied the potential of alpha-interferon (IFN-alpha) to enhance alpha-fetoprotein (AFP) and thus alter the localization of 125I-labeled antibody to the human hepatoma xenograft in athymic mice using monoclonal antibody (MAb) 19F12, which recogniz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b82e7a37c4f3f2356d31f1eaba810259
https://doi.org/10.1159/000227144
https://doi.org/10.1159/000227144
Autor:
Yoichi Sakata, Toshiya Yamagishi, Takashi Watanabe, Tomoyuki Kuwata, Shigeki Matsubara, Mitsuaki Suzuki, Kazuhiro Nagaike
Publikováno v:
The journal of obstetrics and gynaecology research. 32(1)
Aim: Hepatocyte growth factor (HGF) was originally identified as a factor that stimulates the mitogenesis of hepatocyte, and also plays a role in maintaining pregnancy. We conducted this study to evaluate the changes in plasma concentrations of HGF a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef19cb83f9d724d5c1fb2144a0c6b166
https://pubmed.ncbi.nlm.nih.gov/16445520
https://pubmed.ncbi.nlm.nih.gov/16445520