Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Kazuhiro, Maki"'
Autor:
Catherine E.M. Simpson, Adrian J. Esterman, Subodh S. Ganu, Kazuhiro Maki, Steve R. Keeley, Emily J. Ward, Margarita D. Tsiros
Objective: The objective of this study was to investigate the impact of daily screening for medical readiness to participate in early mobilisation in the paediatric intensive care unit (PICU), on reducing time to mobilisation and to explore the safet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91a6dcaf76a8d3b0f396750ee18600d0
https://hdl.handle.net/11541.2/27469
https://hdl.handle.net/11541.2/27469
RUNX1/EVI1, which blocks myeloid differentiation, inhibits CCAAT?enhancer binding protein ? function
Publikováno v:
Cancer Science. 98:1752-1757
The RUNX1/EVI1 chimeric transcription factor produced by t(3;21) causes leukemic transformation in hematopoietic stem cell tumors, possibly through a differentiation block of malignant myeloid progenitors. A dominant negative effect over wild-type RU
Publikováno v:
Biochemical and Biophysical Research Communications. 347:517-526
TEL is an ETS family transcription factor that is critical for maintaining hematopoietic stem cells in adult bone marrow. To investigate the roles of TEL in myeloid proliferation and differentiation, we introduced TEL cDNA into mouse myeloid 32Dcl3 c
Publikováno v:
Cancer Research. 65:6612-6621
We have cloned a novel TEL/protein tyrosine phosphatase receptor-type R (PTPRR) chimeric gene generated by inv(12)(p13q13). PTPRR is the first protein tyrosine phosphatase identified as a fusion partner of TEL. The chimeric gene fused exon 4 of the T
Autor:
Yuichi Nakamura, Kazuhiro Maki, Ko Sasaki, Kazuo Waga, Hisako Gunji, Kinuko Mitani, Fumihiko Nakamura
Publikováno v:
Biochemical and Biophysical Research Communications. 322:623-630
The TEL/AML1 chimeric gene is generated by the t(12;21) translocation in pre-B cell acute lymphoblastic leukemia. TEL/AML1 consists of the helix-loop-helix (HLH) dimerization domain from TEL and almost the entire of AML1, but loses the ETS DNA-bindin
Autor:
Masaki Noda, Motoshi Ichikawa, Sachiko Seo, Akira Hangaishi, Tetsuya Yamagata, Yoshinobu Nakanishi, Hideaki Oda, Hisamaru Hirai, Takahiro Suzuki, Akiko Shiratsuchi, Tetsuya Nakamoto, Tomoko Matsumura, Toshiki Saito, Kazuhiro Maki, Shin-Ichi Aizawa, Keiichi Inoue, Takashi Asai
Publikováno v:
Genes to Cells. 9:575-589
CIZ (Cas interacting zinc finger protein), also called Nmp4 (nuclear matrix protein 4), is a nucleo-cytoplasmic shuttling transcription factor that regulates the expression of collagen and matrix metalloproteinases. CIZ/Nmp4 was originally cloned by
Autor:
Ying Qiao, Seishi Ogawa, Yuko Sato, Koichiro Yuji, A Kunisato, Lili Wang, Kazuhiro Maki, Hisamaru Hirai, Yasuhito Nannya, Kinuko Mitani, Noriko Hosoya, Akira Hangaishi, Yoichi Imai, Koji Izutsu
Publikováno v:
Leukemia. 17:1112-1120
ETS variant gene 6 (ETV6)/translocation, ETS, leukemia (TEL)-involving chromosomal translocations are frequently observed in various hematologic neoplasms. We describe here a novel ETV6-involving translocation, t(12;13)(p13;q14), found in the case of
Publikováno v:
American Journal of Hematology. 72:138-142
The t(10;11)(p12-14;q14-21) is a non-random translocation that results in the fusion of CALM gene on chromosome 11 with AF10 gene on chromosome 10. This translocation is observed in acute myeloid leukemia, acute lymphoblastic leukemia, and lymphoblas
Publikováno v:
British Journal of Haematology. 158:283-285
Autor:
Honoka Arai, Yuichi Nakamura, Kazuo Waga, Ko Sasaki, Mineo Kurokawa, Kinuko Mitani, Yoichi Imai, Hisamaru Hirai, Kazuhiro Maki
Publikováno v:
Biochemical and Biophysical Research Communications. 299:116-125
TEL is a nuclear phosphoprotein that belongs to a member of the ETS family transcription factors. TEL acts as a tumor suppressor and is essential for establishing hematopoiesis in neonatal bone marrow. Because TEL possesses multiple putative mitogen-