Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Kazuhiro, Kitazumi"'
Publikováno v:
Journal of Pharmacological Sciences, Vol 93, Iss 2, Pp 204-209 (2003)
ABSTRACT: Melatonin, a major hormone secreted by the pineal gland, is known to play an important role in regulation of the circadian rhythm. (N-[3-(3-cyanopyrazolo[1,5-a]pyrimidin-7-yl)phenyl]-N-ethylacetamide (zaleplon) is a non-benzodiazepine hypno
Externí odkaz:
https://doaj.org/article/6e51300570b54f12b7b7af804c5fed24
Publikováno v:
Journal of Pharmacological Sciences. 94:246-251
The encephalographic (EEG) properties of zaleplon were investigated in comparison with those of other sedative hypnotics in conscious rats with chronically implanted electrodes. The oral administration of zaleplon (0.25-1.0 mg/kg), triazolam (0.0625-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20fc570b8a4a898544f04e8f6412e620
https://doi.org/10.1254/jphs.94.246
https://doi.org/10.1254/jphs.94.246
Autor:
Kazuhiro Kitazumi, Kenji Tasaka
Publikováno v:
Biochemical Pharmacology. 46:455-464
Treatment of porcine aortic endothelial cells with thrombin induced a time- and dose-dependent expression of preproendothelin-1 (PPET-1) mRNA. The thrombin-induced expression of PPET-1 mRNA was markedly inhibited by calphostin C, a specific inhibitor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39c5510635a9f2acb9b766a40365cf2e
https://doi.org/10.1016/0006-2952(93)90522-x
https://doi.org/10.1016/0006-2952(93)90522-x
Publikováno v:
Oncology reports. 23(2)
The 9-beta-D-arabinofuranosylguanine (ara-G), an active compound of nelarabine, demonstrates potent cytotoxicity specifically on T-cell malignancies. In cells, ara-G is phosphorylated to ara-G triphosphate (ara-GTP), which is subsequently incorporate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::43f306b0989460dc860efb7cc693b024
https://pubmed.ncbi.nlm.nih.gov/20043113
https://pubmed.ncbi.nlm.nih.gov/20043113
Autor:
Kazuhiro Kitazumi, Kenji Tasaka
Publikováno v:
Biochemical Pharmacology. 43:1701-1709
Thrombin-stimulated secretion of endothelin-1 (ET-1) from porcine aortic endothelial cells was inhibited in the presence of 3,4,5-trimethoxybenzoic acid 8-(diethylamino)octyl ester (TMB-8), trifluoperazine and N-(6-aminohexyl)-5-chloro-1-naphthalenes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::882933e7f2945d69b3247560444dd4b6
https://doi.org/10.1016/0006-2952(92)90699-j
https://doi.org/10.1016/0006-2952(92)90699-j
Autor:
Keiji Izushi, Mitsunobu Mio, Masaaki Akagi, Kenji Tasaka, Chiaki Kamei, Kazuhiro Kitazumi, Shigehiro Masaki
Publikováno v:
Immunopharmacology and Immunotoxicology. 14:191-205
Epinastine caused an inhibition of histamine release from rat peritoneal mast cells induced by both antigen-antibody reaction and compound 48/80. Epinastine was similarly effective in inhibiting compound 48/80-induced histamine release not only from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29d6953ebed5ceace99cae7202fea241
https://doi.org/10.3109/08923979209009219
https://doi.org/10.3109/08923979209009219
Publikováno v:
Oncology Reports. 23
The 9-beta-D-arabinofuranosylguanine (ara-G), an active compound of nelarabine, demonstrates potent cytotoxicity specifically on T-cell malignancies. In cells, ara-G is phosphorylated to ara-G triphosphate (ara-GTP), which is subsequently incorporate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::722fa706b4a5e2bfca69057c698d04bc
https://doi.org/10.3892/or_00000661
https://doi.org/10.3892/or_00000661
Publikováno v:
Biochemical Pharmacology. 42:1079-1085
The effects of certain microtubule-disrupting agents on endothelin-1 (ET-1) secretion from porcine aortic endothelial cells were studied. When endothelial cells were treated with thrombin (1 unit/mL), a significant increase in ET-1 secretion was dete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e70394278c2329f617cd0b2b36172dab
https://doi.org/10.1016/0006-2952(91)90291-c
https://doi.org/10.1016/0006-2952(91)90291-c
Autor:
Kazuhiro Kitazumi, Saburo Aimoto, Keizo Ohnaka, Hajime Nawata, Ryoichi Takayanagi, Toshiharu Shiba, Chikahisa Takasaki, Kenji Tasaka, Katsuyuki Nishiki, Yasuo Furukawa
Publikováno v:
European Journal of Pharmacology. 198:165-169
The three chimera peptides of sarafotoxins S6b (SRTb) and S6c (SRTc), [Thr 2 SRTb, [Asn 4 ]SRTb and [Glu 9 ]SRTb, were synthesized chemically. From the comparisons of lethality, vasoconstrictor activity and receptor binding activity of SRTb, SRTa ([A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74d58121b513e7e05b2584a8f11e4744
https://doi.org/10.1016/0014-2999(91)90616-x
https://doi.org/10.1016/0014-2999(91)90616-x
Publikováno v:
Naunyn-Schmiedeberg's archives of pharmacology. 366(2)
Although structurally not a benzodiazepine, 3'-(3-cyanopyrazolo [1,5-a] pyrimidin-7-yl)- N-ethylacetamide (zaleplon) it acts via the benzodiazepine site of the GABA(A) receptor. In the present study, we investigated the effects of zaleplon on learnin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b150d31e5bca303959aa2527195987b
https://pubmed.ncbi.nlm.nih.gov/12122506
https://pubmed.ncbi.nlm.nih.gov/12122506