Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Kazuhiro, Daino"'
Autor:
Daisuke Iizuka, Megumi Sasatani, Atsuko Ishikawa, Kazuhiro Daino, Tokuhisa Hirouchi, Kenji Kamiya
Publikováno v:
PLoS ONE, Vol 18, Iss 10, p e0292643 (2023)
Among the small intestinal tumors that occur in irradiated mice of the established mouse model B6/B6-Chr18MSM-F1 ApcMin/+, loss of heterozygosity analysis can be utilized to estimate whether a deletion in the wild-type allele containing the Adenomato
Externí odkaz:
https://doaj.org/article/6db53c3faaa94dc59252601f55582dea
Autor:
Takafumi Nakayama, Masaaki Sunaoshi, Yi Shang, Mizuki Takahashi, Takato Saito, Benjamin J Blyth, Yoshiko Amasaki, Kazuhiro Daino, Yoshiya Shimada, Akira Tachibana, Shizuko Kakinuma
Publikováno v:
PLoS ONE, Vol 18, Iss 1, p e0280560 (2023)
Calorie restriction (CR) suppresses not only spontaneous but also chemical- and radiation-induced carcinogenesis. Our previous study revealed that the cancer-preventive effect of CR is tissue dependent and that CR does not effectively prevent the dev
Externí odkaz:
https://doaj.org/article/d593dc7b262f475e8791f1b1924e1242
Publikováno v:
Anticancer Research. 43:2551-2559
Autor:
Hiromi Yanagihara, Takamitsu Morioka, Shunsuke Yamazaki, Yutaka Yamada, Hirotaka Tachibana, Kazuhiro Daino, Chizuru Tsuruoka, Yoshiko Amasaki, Mutsumi Kaminishi, Tatsuhiko Imaoka, Shizuko Kakinuma
Publikováno v:
Journal of Radiation Research. 64:622-631
Recent studies have identified interstitial deletions in the cancer genome as a radiation-related mutational signature, although most of them do not fall on cancer driver genes. Pioneering studies in the field have indicated the presence of loss of h
Publikováno v:
Journal of Radiation Research. 64:273-283
Cancer risk after exposure to ionizing radiation can vary between individuals and populations, but the impact of factors governing those variations is not well understood. We previously conducted a series of carcinogenesis experiments using a rat mod
Autor:
Nishimura, Mayumi, Imaoka, Tatsuhiko, Daino, Kazuhiro, Nishimura, Yukiko, Kokubo, Toshiaki, Takabatake, Masaru, Kakinuma, Shizuko, Shimada, Yoshiya, Mayumi, Nishimura, Tatsuhiko, Imaoka, Kazuhiro, Daino, Yukiko, Nishimura, Toshiaki, Kokubo, Masaru, Takabatake, Shizuko, Kakinuma, Yoshiya, Shimada
Publikováno v:
Anticancer Research. 42(5):2415-2423
Background/Aim: Genetic and environmental factors interact to dictate the risk of cancer, and animal models are expected to provide avenues for identifying such interactions. The aim of the study was to clarify the genetic susceptibility of Copenhage
Autor:
Mayumi Nishimura, Kazuhiro Daino, Maki Fukuda, Ikuya Tanaka, Hitomi Moriyama, Kaye Showler, Yukiko Nishimura, Masaru Takabatake, Toshiaki Kokubo, Atsuko Ishikawa, Kazumasa Inoue, Masahiro Fukushi, Shizuko Kakinuma, Tatsuhiko Imaoka, Yoshiya Shimada
Publikováno v:
PLoS ONE, Vol 16, Iss 8, p e0255968 (2021)
Copenhagen rats are highly resistant to mammary carcinogenesis, even after treatment with chemical carcinogens and hormones; most studies indicate that this is a dominant genetic trait. To test whether this trait is also dominant after radiation expo
Externí odkaz:
https://doaj.org/article/f809fc58fb0444b397ec183fc7dd069b
Autor:
Tatsuhiko Imaoka, Mayumi Nishimura, Kazuhiro Daino, Ayaka Hosoki, Ken-ichi Kudo, Daisuke Iizuka, Kento Nagata, Masaru Takabatake, Yukiko Nishimura, Toshiaki Kokubo, Takamitsu Morioka, Kazutaka Doi, Yoshiya Shimada, Shizuko Kakinuma
Publikováno v:
Radiation Protection Dosimetry. 198:1036-1046
The uncertain cancer risk of protracted radiation exposure at low dose rates is an important issue in radiological protection. Tissue stem/progenitor cells are a supposed origin of cancer and may contribute to the dose-rate effect on carcinogenesis.
Autor:
Yuzuki Nakamura, Jo Kubota, Yukiko Nishimura, Kento Nagata, Mayumi Nishimura, Kazuhiro Daino, Atsuko Ishikawa, Takehito Kaneko, Tomoji Mashimo, Toshiaki Kokubo, Masaru Takabatake, Kazumasa Inoue, Masahiro Fukushi, Masami Arai, Mitsue Saito, Yoshiya Shimada, Shizuko Kakinuma, Tatsuhiko Imaoka
Publikováno v:
Cancer Science. 113:3362-3375
Autor:
MAYUMI NISHIMURA, TATSUHIKO IMAOKA, KAZUHIRO DAINO, YUKIKO NISHIMURA, TOSHIAKI KOKUBO, MASARU TAKABATAKE, SHIZUKO KAKINUMA, YOSHIYA SHIMADA
Publikováno v:
Anticancer Research. 42:2415-2423
Genetic and environmental factors interact to dictate the risk of cancer, and animal models are expected to provide avenues for identifying such interactions. The aim of the study was to clarify the genetic susceptibility of Copenhagen rats to sponta