Zobrazeno 1 - 10
of 585
pro vyhledávání: '"Kazuhiro, Aoki"'
Publikováno v:
Cell Structure and Function, Vol 49, Iss 2, Pp 123-133 (2024)
Anhydrobiosis, a phenomenon in which organisms survive extreme dehydration by entering a reversible ametabolic state, is a remarkable example of survival strategies. This study focuses on anhydrobiosis in tardigrades, which are known for their resili
Externí odkaz:
https://doaj.org/article/3606575845314a3181ae996051562a9f
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Fabry disease is an X-linked lysosomal storage disorder caused by deficiency of the lysosomal enzyme ⍺-galactosidase-A (⍺-Gal A), resulting in widespread accumulation of terminal galactose-containing glycosphingolipids (GSLs) and the imp
Externí odkaz:
https://doaj.org/article/39a61f23e43a431bb7f1fc26b70a1766
Autor:
Richard N. Bohnsack, Sandeep K. Misra, Jianfang Liu, Mayumi Ishihara-Aoki, Michaela Pereckas, Kazuhiro Aoki, Gang Ren, Joshua S. Sharp, Nancy M. Dahms
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract The cation-independent mannose 6-phosphate receptor (CI-MPR) is clinically significant in the treatment of patients with lysosomal storage diseases because it functions in the biogenesis of lysosomes by transporting mannose 6-phosphate (M6P)
Externí odkaz:
https://doaj.org/article/35234b80f7a143668b071c3cf37ff669
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Biomolecular condensates are broadly implicated in both normal cellular regulation and disease. Consequently, several chemical biology and optogenetic approaches have been developed to induce phase separation of a protein of interest. Howeve
Externí odkaz:
https://doaj.org/article/2734a9f4aa924704ae35e1798669302a
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Although bone dehiscence may occur during orthodontic tooth movement into the narrow alveolar ridge, a non-invasive prevention method is yet to be fully established. We show for the first time prevention of bone dehiscence associated with or
Externí odkaz:
https://doaj.org/article/ee08ebb56902465299def302153bb128
Publikováno v:
npj Systems Biology and Applications, Vol 10, Iss 1, Pp 1-10 (2024)
Abstract Bow-tie architecture is a layered network structure that has a narrow middle layer with multiple inputs and outputs. Such structures are widely seen in the molecular networks in cells, suggesting that a universal evolutionary mechanism under
Externí odkaz:
https://doaj.org/article/ce1a3bf16fd34ab48d237f11c99ea77a
Publikováno v:
Journal of Physical Fitness and Sports Medicine, Vol 13, Iss 1, Pp 9-17 (2024)
In this study, the characteristics of the athletic careers of Japanese college baseball players were identified, and relationships between their athletic careers and levels of performance and injury were analyzed. A questionnaire survey was conducted
Externí odkaz:
https://doaj.org/article/770caaf88e8148da8030c918ecb1b278
Autor:
Eiko Yoshida1,2, Kazuhiro Aoki1, Yu Sasaki1, Hinako Izuhara1, Tsutomu Takahashi3, Yasuyuki Fujiwara3, Tomoya Fujie1, Ke Du4, Komyo Eto5, Yo Shinoda3 shinoda@toyaku.ac.jp, Toshiyuki Kaji1 t-kaji@rs.tus.ac.jp
Publikováno v:
Journal of Toxicological Sciences. 2024, Vol. 49 Issue 5, p214-248. 8p.
Autor:
Sunmyoung Lee, Louis-David Leclercq, Yann Guerardel, Christine M. Szymanski, Thomas Hurtaux, Tamara L. Doering, Takane Katayama, Kiyotaka Fujita, Kazuhiro Aoki, Kiyoko F. Aoki-Kinoshita
Publikováno v:
BBA Advances, Vol 6, Iss , Pp 100126- (2024)
Glycoconjugates are present on microbial surfaces and play critical roles in modulating interactions with the environment and the host. Extensive research on microbial glycans, including elucidating the structural diversity of the glycan moieties of
Externí odkaz:
https://doaj.org/article/311d9b4d017747c5b5e9074f35fdcecf
Autor:
Yayoi Toyooka, Kazuhiro Aoki, Fumiko Matsukawa Usami, Sanae Oka, Azusa Kato, Toshihiko Fujimori
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract The extracellular signal-regulated kinase (ERK) is a serine/threonine kinase that is known to regulate cellular events such as cell proliferation and differentiation. The ERK signaling pathway is activated by fibroblast growth factors, and i
Externí odkaz:
https://doaj.org/article/9ca4e612385749ac92caa56dc9d9b4de