Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Kazuhiko S.K. Uchida"'
Autor:
Minji Jo, Motoko Takahashi, Hiroshi Masumoto, Katsushi Shibata, Kazuhiko S.K. Uchida, Toru Hirota, Kota Nagasaka, Tatsuo Fukagawa, Kozo Tanaka, Norihisa Shindo
Publikováno v:
Curr Biol
The spindle-assembly checkpoint facilitates mitotic fidelity by delaying anaphase onset in response to microtubule vacancy at kinetochores. Following microtubule attachment, kinetochores receive microtubule-derived force, which causes kinetochores to
Publikováno v:
Cell reports. 34(3)
Intercellular karyotype diversity, or aneuploidy, is a widespread feature of cancers propagated through continuous mitotic chromosome segregation errors, the condition called chromosomal instability. The protease separase is an essential enzyme that
Autor:
Kazuhiko S.K. Uchida, Norihisa Shindo, Hiroshi Masumoto, Tatsuo Fukagawa, Kozo Tanaka, Kota Nagasaka, Toru Hirota, Minji Jo, Motoko Takahashi
Publikováno v:
SSRN Electronic Journal.
The spindle-assembly checkpoint facilitates mitotic fidelity by delaying anaphase onset in response to microtubule vacancy at kinetochores. Following microtubule attachment, kinetochores receive microtubule-derived forces, which causes kinetochores t
Autor:
Kazuhiko S.K. Uchida, Jennifer G. DeLuca, Kosuke Sako, Youko Hirayama, Abe Yusuke, Kentaro Takagaki, Toru Hirota, Jacob A. Herman
Publikováno v:
Developmental Cell. 36:487-497
Incorrect attachment of kinetochore microtubules is the leading cause of chromosome missegregation in cancers. The highly conserved chromosomal passenger complex (CPC), containing mitotic kinase Aurora B as a catalytic subunit, ensures faithful chrom
Autor:
Yoshie Chiba, Zixian Jiang, Toru Hirota, Yoshikazu Johmura, Shige H. Yoshimura, Midori Shimada, Kazuhiko S.K. Uchida, Makoto Nakanishi, Koutarou Nishimura, Keiko Kono, Narumi Suzuki, Katashi Deguchi
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Animal cells undergo rapid rounding during mitosis, ensuring proper chromosome segregation, during which an outward rounding force abruptly increases upon prometaphase entry and is maintained at a constant level during metaphase. Initial cortical ten
Autor:
Kazuhiko S.K. Uchida, Toru Hirota
Publikováno v:
DNA Replication, Recombination, and Repair ISBN: 9784431558712
If the cell cycle were driven solely by its molecular engine, powered by oscillations in the activity of cyclin-dependent kinases, then transmission of the genome from parent to daughter cells would be far from accurate. Therefore, a robust surveilla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e6947433a12461db401d314cd2c1bd3
https://doi.org/10.1007/978-4-431-55873-6_17
https://doi.org/10.1007/978-4-431-55873-6_17
Autor:
Akira Yasui, Kensaku Mizuno, Kazuhiko S.K. Uchida, Shuhei Chiba, Shiro Sugino, Go Itoh, Shin Ichiro Kanno, Toru Hirota, Kana Watanabe, Kozo Tanaka
Publikováno v:
The EMBO Journal. 30:130-144
Proper attachment of microtubules to kinetochores is essential for accurate chromosome segregation. Here, we report a novel protein involved in kinetochore–microtubule attachment, chromosome alignment-maintaining phosphoprotein (CAMP) (C13orf8, ZNF
Autor:
Kazuhiko S.K. Uchida, Kentaro Takagaki, Toru Hirota, Youko Hirayama, Kazuki Kumada, Tetsuo Noda
Publikováno v:
The Journal of Cell Biology
The spindle assembly checkpoint (SAC) monitors the attachment of microtubules to the kinetochore and inhibits anaphase when microtubule binding is incomplete. The SAC might also respond to tension; however, how cells can sense tension and whether its
Autor:
Makoto Otsuki, Mamoru Suzuki, Masahiro Horio, Shigeyuki Kano, Kazuhiko S.K. Uchida, Masaaki Shimada, Masaaki Endo
Publikováno v:
Japanese Journal of Tropical Medicine and Hygiene. 20:29-35