Výsledky vyhledávání - "Kazuhiko Iitsuka"

Akademický článek

Molecular mechanisms underlying the pilsicainide-induced stabilization of hERG proteins in transfected mammalian cells

Autor: Takeshi Onohara, MD, Ichiro Hisatome, MD, Yasutaka Kurata, MD, Peili Li, MD, Tomomi Notsu, PhD, Kumi Morikawa, PhD, Naoyuki Otani, MD, Akio Yoshida, MD, Kazuhiko Iitsuka, MD, Masaru Kato, MD, Junichiro Miake, MD, Haruaki Ninomiya, MD, Katsumi Higaki, PhD, Yasuaki Shirayoshi, PhD, Takashi Nishihara, BE, Toshiyuki Itoh, PhD, Yoshinobu Nakamura, MD, Motonobu Nishimura, MD

Publikováno v: Journal of Arrhythmia, Vol 33, Iss 3, Pp 226-233 (2017)

Background: Pilsicainide, classified as a relatively selective Na+ channel blocker, also has an inhibitory action on the rapidly-activating delayed-rectifier K+ current (IKr) through human ether-a-go-go-related gene (hERG) channels. We studied the ef

Externí odkaz: https://doaj.org/article/79c1cda0789f496394eafca2f1b97d00

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Akademický článek

Characterization of the novel mutant A78T-HERG from a long QT syndrome type 2 patient: Instability of the mutant protein and stabilization by heat shock factor 1

Publikováno v: Journal of Arrhythmia, Vol 32, Iss 5, Pp 433-440 (2016)

Background: The human ether-a-go-go-related gene (HERG) encodes the α-subunit of rapidly activating delayed-rectifier potassium channels. Mutations in this gene cause long QT syndrome type 2 (LQT2). In most cases, mutations reduce the stability of t

Externí odkaz: https://doaj.org/article/5d4db3e2c36644959f8332cdfd40f7fb

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Different Effects of Pulmonary Vein Isolation on Quality of Life Between Patients with Persistent and Paroxysmal Atrial Fibrillation

Autor: Kazuhiko Iitsuka, Kazuyoshi Ogura, Masahiko Kato, Takuya Tomomori, Akihiro Okamura, Junichiro Miake, Daiki Tsujimoto, Masaru Kato, Kazuhiro Yamamoto

Publikováno v: International Heart Journal. 60:1328-1333

The effect of restoring sinus rhythm by pulmonary vein isolation (PVI) on the quality of life (QOL) of patients with persistent atrial fibrillation (PerAF) has not been adequately investigated. This study was performed to compare the changes in QOL a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da9a96ddf2b9b8fdee208e83a4578912
https://doi.org/10.1536/ihj.19-201

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Pharmacokinetic Drug Interaction Between Rosuvastatin and Tanjin in Healthy Volunteers and Rats

Autor: Jie Yang, Kazuhiko Iitsuka, Junichi Hasegawa, Miwa Yamamoto, Akiko Matsuda, Yusuke Endo

Publikováno v: Yonago Acta Medica. 2019, 62(1), 77-84

BACKGROUND: Tanjin is an herbal medicine made from the root of salvia miltiorrhiza. It is predominantly given to arteriosclerotic patients as a supplement to ameliorate the clinical symptoms of cardiovascular diseases. In China, tanjin is used freque

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::703fd85944bbd5c92ac43bb241ba01e4
http://repository.lib.tottori-u.ac.jp/6300

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Molecular mechanisms underlying the pilsicainide-induced stabilization of hERG proteins in transfected mammalian cells

Autor: Akio Yoshida, Yasutaka Kurata, Haruaki Ninomiya, Toshiyuki Itoh, Takeshi Onohara, Katsumi Higaki, Peili Li, BE Takashi Nishihara, Motonobu Nishimura, Yasuaki Shirayoshi, Kumi Morikawa, Kazuhiko Iitsuka, Junichiro Miake, Masaru Kato, Ichiro Hisatome, Naoyuki Otani, Tomomi Notsu, Yoshinobu Nakamura

Publikováno v: Journal of Arrhythmia
Journal of Arrhythmia, Vol 33, Iss 3, Pp 226-233 (2017)

Background Pilsicainide, classified as a relatively selective Na + channel blocker, also has an inhibitory action on the rapidly-activating delayed-rectifier K + current ( I Kr ) through human ether-a-go-go-related gene (hERG) channels. We studied th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::058161b0a1da2b572bc9697e619323b1
https://doi.org/10.1016/j.joa.2016.09.003

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Impact of postprocedural antiarrhythmic drug therapy with bepridil on maintaining sinus rhythm after catheter ablation for persistent atrial fibrillation

Autor: Junichiro Miake, Kazuhiro Yamamoto, Kazuyoshi Ogura, Masaru Kato, Kazuhiko Iitsuka, Takehito Kondo

Publikováno v: Journal of Cardiology. 68:229-235

Background Although several studies have assessed the predictors of recurrent atrial fibrillation (AF) after catheter ablation for persistent AF, the impact of antiarrhythmic drug (AAD) therapy on maintaining sinus rhythm after catheter ablation for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd523ce6548271de738396d5cf321dbe
https://doi.org/10.1016/j.jjcc.2015.09.012

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Pre-ablation levels of brain natriuretic peptide are independently associated with the recurrence of atrial fibrillation after radiofrequency catheter ablation in patients with nonvalvular atrial fibrillation

Autor: Akihiro Okamura, Masaru Kato, Kazuhiko Iitsuka, Kazuyoshi Ogura, Takuya Tomomori, Daiki Tsujimoto, Kazuhiro Yamamoto, Junichiro Miake, Masahiko Kato

Publikováno v: Heart and Vessels

Association between pre-ablation levels of biomarkers of cardiac and endothelial dysfunctions, CHADS2, CHA2DS2-VASc, and APPLE scores and the recurrence of atrial fibrillation (AF) after radiofrequency catheter ablation has not been fully studied. A

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9809f75cfd9f1f785a7406cfcced77cb
https://pubmed.ncbi.nlm.nih.gov/30238353

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