Zobrazeno 1 - 10
of 126
pro vyhledávání: '"Kazuhiko Aoyagi"'
Autor:
Shihori Tanabe, Sabina Quader, Ryuichi Ono, Horacio Cabral, Kazuhiko Aoyagi, Akihiko Hirose, Edward J. Perkins, Hiroshi Yokozaki, Hiroki Sasaki
Publikováno v:
Onco, Vol 3, Iss 1, Pp 13-25 (2023)
Because activity of the epithelial–mesenchymal transition (EMT) is involved in anti-cancer drug resistance, cancer malignancy, and shares some characteristics with cancer stem cells (CSCs), we used artificial intelligence (AI) modeling to identify
Externí odkaz:
https://doaj.org/article/cb6784a71e6743489888765207563c89
Autor:
Satoyo Oda, Mineko Ushiama, Wataru Nakamura, Masahiro Gotoh, Noriko Tanabe, Tomoko Watanabe, Yoko Odaka, Kazuhiko Aoyagi, Hiromi Sakamoto, Takeshi Nakajima, Kokichi Sugano, Teruhiko Yoshida, Yuichi Shiraishi, Makoto Hirata
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Genetic testing of the APC gene by sequencing analysis and MLPA is available across commercial laboratories for the definitive genetic diagnosis of familial adenomatous polyposis (FAP). However, some genetic alterations are difficult to detect using
Externí odkaz:
https://doaj.org/article/16a379c2dd3e48d5a80a14093eefaf68
Autor:
Tatsuhiro Shibata, Akiko Kokubu, Shigeru Saito, Mako Narisawa-Saito, Hiroki Sasaki, Kazuhiko Aoyagi, Yuki Yoshimatsu, Yuji Tachimori, Ryoji Kushima, Tohru Kiyono, Masayuki Yamamoto
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 13, Iss 9, Pp 864-873 (2011)
Esophageal squamous cancer (ESC) is one of the most aggressive tumors of the gastrointestinal tract. A combination of chemotherapy and radiation therapy (CRT) has improved the clinical outcome, but the molecular background determining the effectivene
Externí odkaz:
https://doaj.org/article/a5402594be194dfa96ee454cc3963237
Autor:
Yosuke Tanaka, Kazuhiko Aoyagi, Keiko Minashi, Rie Komatsuzaki, Masayuki Komatsu, Fumiko Chiwaki, Masashi Tamaoki, Takao Nishimura, Naoki Takahashi, Ichiro Oda, Yuji Tachimori, Tokuzo Arao, Kazuto Nishio, Shigehisa Kitano, Kenta Narumi, Kazunori Aoki, Satoshi Fujii, Atsushi Ochiai, Teruhiko Yoshida, Manabu Muto, Yasuhide Yamada, Hiroki Sasaki
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0143804 (2015)
Definitive chemoradiotherapy (CRT) is a less invasive therapy for esophageal squamous cell carcinoma (ESCC). Five-year survival rate of locally advanced ESCC patients by definitive CRT were 37%. We previously reported that tumor-specific cytotoxic T-
Externí odkaz:
https://doaj.org/article/17f86009996841d4a7eeb10a20f4fbdf
Autor:
Masami Suzuki, Fumiko Chiwaki, Yumi Sawada, Maho Ashikawa, Kazuhiko Aoyagi, Takeshi Fujita, Kazuyoshi Yanagihara, Masayuki Komatsu, Minoru Narita, Tsutomu Suzuki, Hiroshi Nagase, Ryoji Kushima, Hiromi Sakamoto, Takeo Fukagawa, Hitoshi Katai, Hitoshi Nakagama, Teruhiko Yoshida, Yasuhito Uezono, Hiroki Sasaki
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0123407 (2015)
The dormancy of tumor cells is a major problem in chemotherapy, since it limits the therapeutic efficacy of anti-tumor drugs that only target dividing cells. One potential way to overcome chemo-resistance is to "wake up" these dormant cells. Here we
Externí odkaz:
https://doaj.org/article/0ea575147661431498c338d3c2f83e28
Autor:
Youichi Higuchi, Motohiro Kojima, Genichiro Ishii, Kazuhiko Aoyagi, Hiroki Sasaki, Atsushi Ochiai
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0129241 (2015)
Fibroblasts are the principal stromal cells that exist in whole organs and play vital roles in many biological processes. Although the functional diversity of fibroblasts has been estimated, a comprehensive analysis of fibroblasts from the whole body
Externí odkaz:
https://doaj.org/article/222474da4afc43f78856a29832cdc292
Autor:
Takeshi Fujita, Fumiko Chiwaki, Ryou-u Takahashi, Kazuhiko Aoyagi, Kazuyoshi Yanagihara, Takao Nishimura, Masashi Tamaoki, Masayuki Komatsu, Rie Komatsuzaki, Keisuke Matsusaki, Hitoshi Ichikawa, Hiromi Sakamoto, Yasuhide Yamada, Takeo Fukagawa, Hitoshi Katai, Hiroyuki Konno, Takahiro Ochiya, Teruhiko Yoshida, Hiroki Sasaki
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0130808 (2015)
Diffuse-type solid tumors are often composed of a high proportion of rarely proliferating (i.e., dormant) cancer cells, strongly indicating the involvement of cancer stem cells (CSCs) Although diffuse-type gastric cancer (GC) patients have a poor pro
Externí odkaz:
https://doaj.org/article/94b73f81ba67482fa2b952678f0c12ae
Autor:
Motohiro Kojima, Youichi Higuchi, Mitsuru Yokota, Genichiro Ishii, Norio Saito, Kazuhiko Aoyagi, Hiroki Sasaki, Atsushi Ochiai
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88018 (2014)
BACKGROUNDS: Peritoneal invasion in colon cancer is an important prognostic factor. Peritoneal invasion can be objectively identified as periotoneal elastic laminal invasion (ELI) by using elastica stain, and the cancer microenvironment formed by the
Externí odkaz:
https://doaj.org/article/b64f55ddb24a4908847ec32c55d87c21
Autor:
Kazuhiko Aoyagi, Keiko Minashi, Hiroyasu Igaki, Yuji Tachimori, Takao Nishimura, Norikazu Hokamura, Akio Ashida, Hiroyuki Daiko, Atsushi Ochiai, Manabu Muto, Atsushi Ohtsu, Teruhiko Yoshida, Hiroki Sasaki
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18196 (2011)
BACKGROUND: Surgical samples have long been used as important subjects for cancer research. In accordance with an increase of neoadjuvant therapy, biopsy samples have recently become imperative for cancer transcriptome. On the other hand, both biopsy
Externí odkaz:
https://doaj.org/article/32539f9fd7ad4496b4df18c17141c3cc
Autor:
Shihori Tanabe, Eger Boonstra, Taehun Hong, Sabina Quader, Ryuichi Ono, Horacio Cabral, Kazuhiko Aoyagi, Hiroshi Yokozaki, Hiroki Sasaki
To reveal the relationship between metallodrugs and cancer malignancy, molecular networks of anti-cancer drugs were analyzed. Molecular networks in several types of cancers were analyzed in Ingenuity Pathway Analysis (IPA). Analysis of carboplatin re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07e2032fb228df33c9014e4f1eaf6e2f
https://doi.org/10.20944/preprints202305.1304.v1
https://doi.org/10.20944/preprints202305.1304.v1
