Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Kazuhiko, Sugahara"'
Autor:
Junitsu Ito, Hak Hotta, Sumio Kawata, Takafumi Saito, Hitoshi Togashi, Kazuhiko Sugahara, Yuko Nishise, Koji Saito, Motoko Nagano-Fujii
Publikováno v:
The Journal of Infectious Diseases. 196:1006-1009
We conducted a retrospective study of 65 patients with chronic hepatitis C, to determine whether the secondary structure of the amino-terminal 120 residues of the hepatitis C virus (HCV) NS3 protein is associated with an increased risk of development
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8348bfd887bd852ff062498a19775c00
https://doi.org/10.1086/521309
https://doi.org/10.1086/521309
Autor:
Koji Saito, Rika Ishii, Kazuhiko Sugahara, Sumio Kawata, Mai Sanjo, Akihiko Suzuki, Hiroaki Haga, Takafumi Saito, Keiko Misawa, Hitoshi Togashi, Etsuko Hattori, Junitsu Ito, Kazuo Okumoto, Tetsuru Karasawa
Publikováno v:
Journal of Gastroenterology. 41:62-69
Bone marrow cells (BMCs) have been shown to differentiate into a liver cell lineage, but little is known about their dynamics following transplantation. BMCs were cultured to investigate the expression of liver-specific genes in vitro and transplante
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::716c6128debc9ca4476841f0358be5bb
https://doi.org/10.1007/s00535-005-1723-8
https://doi.org/10.1007/s00535-005-1723-8
Autor:
Kuniaki Nakano, Koji Saito, Testuru Karasawa, Hisayoshi Watanabe, Hitoshi Togashi, Kazuhiko Sugahara, Sumio Kawata, Junitsu Ito, Shun Kudo, Takafumi Saito
Publikováno v:
Hepatology Research. 33:14-18
The efficacy of interferon (IFN) therapy for chronic hepatitis C is dependent on compliance. Anorexia is an important adverse effect in determining compliance. To clarify the mechanisms underlying anorexia, the level of ghrelin was determined during
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d5fff47e31f89e6cf667011c6109832
https://doi.org/10.1016/j.hepres.2005.06.008
https://doi.org/10.1016/j.hepres.2005.06.008
Autor:
Koji Saito, Keiko Misawa, Takafumi Saito, Kazuhiko Sugahara, Junitsu Ito, Sumio Kawata, Kazuo Okumoto, Mai Sanjyo, Etsuko Hattori, Akihiko Suzuki, Hitoshi Togashi, Tadashi Takeda
Publikováno v:
Hepatology Research. 31:7-12
Notch signalling pathway plays an important role in cell differentiation. To investigate the implications of Notch signalling in the differentiation of rat bone marrow (BM) cells into a liver cell lineage, we used cultured BM cells to examine the mRN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b271b49f069bbe54992b7eb0c25d425
https://doi.org/10.1016/j.hepres.2004.11.005
https://doi.org/10.1016/j.hepres.2004.11.005
Autor:
Tohru Adachi, Kazuhiko Sugahara, Junitsu Ito, Akihiko Suzuki, Shigenobu Kasai, Sumio Kawata, Hitoshi Togashi
Publikováno v:
Hepatology. 41:1272-1281
The proliferation of hepatic stellate cells (HSCs) is a critical step in hepatic fibrogenesis. Platelet-derived growth factor (PDGF) is the most potent mitogen for HSCs. We investigated the role of nonphagocytic NAD(P)H oxidase–derived reactive oxy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6e6a19fbfc23bea8bbf41ee6cb8183b
https://doi.org/10.1002/hep.20719
https://doi.org/10.1002/hep.20719
Autor:
Tadashi Takeda, Tohru Adachi, Koji Saito, Takafumi Saito, Junitsu Ito, Etsuko Hattori, Hisayoshi Watanabe, Kazuo Okumoto, Sumio Kawata, Kazuhiko Sugahara, Hitoshi Togashi
Publikováno v:
Hepatology Research. 27:309-314
OBJECTIVES: Interleukin-10 (IL-10) has been implicated in immune deficiency in patients with cancer. The relationship of this cytokine as measured in serum to anti-tumor immunity and prognosis was investigated in unresectable hepatocellular carcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebd1004805014dec1f4409f4659dd454
https://doi.org/10.1016/j.hepres.2003.07.002
https://doi.org/10.1016/j.hepres.2003.07.002
Autor:
Seiji Hongo, Yoko Matsuzaki, Kazuhiko Sugahara, Zhu-Nan Li, Yasushi Muraki, Emi Tsuchiya, Kiyoto Nakamura, Kanetsu Sugawara
Publikováno v:
Virology. 285(1):153-164
The hemagglutinin-esterase (HE) glycoprotein of influenza C virus is composed of three domains: a stem domain active in membrane fusion (F), an acetylesterase domain (E), and a receptor-binding domain (R). The protein contains eight N-linked glycosyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2168bb3cb48b114c8a526f97b6da16ab
Autor:
Yoko Matsuzaki, Emi Tsuchiya, Kazuhiko Sugahara, Kanetsu Sugawara, Seiji Hongo, Kiyoto Nakamura, Zhu-Nan Li
Publikováno v:
Journal of General Virology. 82:1085-1093
The sites for fatty acylation, disulphide bond formation and phosphorylation of influenza C virus CM2 were investigated by site-specific mutagenesis. Cysteine 65 in the cytoplasmic tail was identified as the site for palmitoylation. Removal of one or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1108d293ef8a3582b3b8c3e34088525
https://doi.org/10.1099/0022-1317-82-5-1085
https://doi.org/10.1099/0022-1317-82-5-1085
Autor:
Hideki Mitsuhashi, Shigeru Ohno, Koji Saito, Nobuo Yamada, Yuki Terui, Taku Matsuo, Tsuneo A. Takahashi, Ryuzo Horiuchi, Hitoshi Togashi, Masanori Aoki, Takafumi Saito, Hisayoshi Watanabe, Haruhide Shinzawa, Kazuhiko Sugahara, Takashi Abe, Masamichi Ishibashi
Publikováno v:
The Tohoku Journal of Experimental Medicine. 193:255-258
We reported on an adolescent who suffered from cholestatic hepatitis after taking a low dose of paracetamol. It was suspected that the condition was brought about by an allergic reaction to paracetamol. Paracetamol is one of the representative intrin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::536f1584e915c7ee8f832390d983d448
https://doi.org/10.1620/tjem.193.255
https://doi.org/10.1620/tjem.193.255
Autor:
Hiroko Haga, Koji Saito, Yoshio Takeda, Kazuhiko Sugahara, Yukio Sugai, Shintaro Miyano, Yuya Onodera, Kazuei Takahashi, Hitoshi Togashi, Hideki Saito, Haruhide Shinzawa, Takafumi Saito, Taku Matsuo, Tsuneo Takahashi
Publikováno v:
The Tohoku Journal of Experimental Medicine. 188:257-263
Fulminant hepatic failure is associated with a high mortality rate. Thus, accurate assessment of hepatic functional reserve and hepatic regeneration is important. We describe a 67-year-old woman who survived subacute hepatic failure. We had an opport
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b356b5283641b6e58887a736bb97c761
https://doi.org/10.1620/tjem.188.257
https://doi.org/10.1620/tjem.188.257