Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Kazuhiko, Higashida"'
Publikováno v:
FEBS Open Bio, Vol 10, Iss 10, Pp 2149-2156 (2020)
Proteolysis is known to play a crucial role in maintaining skeletal muscle mass and function. Autophagy is a conserved intracellular process for the bulk degradation of proteins in lysosomes. Although nutrient starvation is known to induce autophagy,
Externí odkaz:
https://doaj.org/article/1dcf3c5316ff44a3bb9254f3fa7cf84b
Autor:
Takeshi Hashimoto, Takumi Yokokawa, Ryoko Narusawa, Yoko Okada, Rika Kawaguchi, Kazuhiko Higashida
Publikováno v:
Journal of Functional Foods, Vol 56, Iss , Pp 84-91 (2019)
We examined the effect of a lactate-based compound containing caffeine with voluntary running exercise on fat loss and metabolic improvement in diet-induced obese (DIO) rats. The rats treated with exercise training (Ex) and the compound (i.e., 1000 m
Externí odkaz:
https://doaj.org/article/806763a502de4656823219e26eaefcc3
Publikováno v:
Journal of Aging and Physical Activity. :1-7
This study aimed to investigate the interaction between sarcopenic obesity and locomotive and nonlocomotive physical activity (PA) on the risk of depressive symptoms in community-dwelling older Japanese women. Participants were 143 community-dwelling
Autor:
Yuji Ogura, Chiaki Kakehashi, Toshinori Yoshihara, Mitsutoshi Kurosaka, Ryo Kakigi, Kazuhiko Higashida, Sei-Etsu Fujiwara, Tatsuo Akema, Toshiya Funabashi
Publikováno v:
PLoS ONE, Vol 15, Iss 10, p e0241382 (2020)
Recent studies of the ketogenic diet, an extremely high-fat diet with extremely low carbohydrates, suggest that it changes the energy metabolism properties of skeletal muscle. However, ketogenic diet effects on muscle metabolic characteristics are di
Externí odkaz:
https://doaj.org/article/6fe180eb247b4cbaaf17f55e13c5687c
Publikováno v:
Journal of applied physiology (Bethesda, Md. : 1985). 132(5)
We examined the effects and interactions of a low-carbohydrate, high-fat (LCHF) diet and voluntary running exercise on bone in older mice. Male 19-mo-old mice were divided into four groups by diet (control vs. LCHF) and exercise (sedentary vs. volunt
Publikováno v:
Journal of Physical Fitness and Sports Medicine, Vol 2, Iss 3, Pp 355-360 (2013)
Skeletal muscle is the primary site of glucose uptake in humans. Glucose transport activity, which is the rate-limiting step in muscle glucose metabolism, is linearly related to the content of the GLUT-4 isoform of the glucose transporter. Therefore,
Externí odkaz:
https://doaj.org/article/08e70705616345ee81cb1d58012444bb
Publikováno v:
Biochemical and Biophysical Research Communications. 531:112-117
Iron deficiency anemia indicates poor nutrition and is a public health problem. Iron deficiency is also associated with muscle weakness. However, the intracellular mechanisms by which iron deficiency induces muscle weakness are obscure. The purpose o
Autor:
Noriko Iida, Ken Nakata, Kazuhiko Higashida, Saki Kitai, Naoya Nakai, Taro Murakami, Sachika Inoue
Publikováno v:
Journal of Nutritional Science and Vitaminology. 66:41-47
Mouse myoblast C2C12 cells are commonly used as a model system for investigating the metabolic regulation of skeletal muscle. As it is therefore important to understand the metabolic features of C2C12 cells, we examined the effect of glucose starvati
Autor:
Kazuhiko Higashida
Publikováno v:
Oleoscience. 20:151-155
Autor:
Naoya Nakai, Noriko Iida, Saki Kitai, Yoshiharu Shimomura, Yasuyuki Kitaura, Kazuhiko Higashida
Publikováno v:
Bioscience, biotechnology, and biochemistry. 86(5)
We examined the effects of branched-chain amino acids (BCAAs) and electrical pulse stimulation (EPS) on the mTORC1 pathway in muscle satellite cells (MSCs) isolated from branched-chain α-keto acid dehydrogenase kinase (BDK) knockout (KO) mice in vit