Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Kazuharu Suyama"'
Autor:
Masanori Murakami, Atsushi Inoue, Takami Kanno, Satoshi Minakami, Hidenori Mochizuki, Yuichi Torii, Shinichi Yamaguchi, Kazuharu Suyama, Masahiro Tsuzuki, Mitsuko Miyamoto, Junko Nakaki
Publikováno v:
European Journal of Pharmacology. 714:312-317
Phosphate binders are used for the treatment of hyperphosphatemia in hemodialysis patients with chronic kidney disease. Sevelamer, a phosphate-binding polymer, has been reported to bind bile acids or fatty acids and thereby decrease its phosphate-bin
Autor:
Kazuharu Suyama, Hiroyuki Meguro, Tadamasa Arai, Hayashi Shinnosuke, Mie Kainoh, Hideki Kawai, Hiroe Hirokawa, Michihiro Ohno, Hideki Inoue, Yoko Koga, Keiyu Oshida, Takumi Aoki
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 22:5118-5122
The discovery that pyrazole-benzyl urea derivatives bearing a 2-molpholinopyrimidine moiety are novel p38α inhibitors is described. A comparative view of the binding modes of SB-203580 and BIRB-796 by structural alignment of two X-ray co-crystal str
Autor:
Shinichi Yamaguchi, Kazuharu Suyama, Kazumi Nishimura, Hiroshi Ueda, Yosuke Iura, Masateru Yamada, Toshiya Takahashi, Shigeo Fujii, Nobuhiro Fuchi, Aiko Nitta, Hiroaki Kaneko, Yumiko Sekiya
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 22:4358-4361
We report the discovery and structure–activity relationship of 2,6-disubstituted pyrazines, which are potent and selective CK2 inhibitors. Lead compound 1 was identified, and derivatives were prepared to develop potent inhibitory activity. As a res
Publikováno v:
Chemistry Letters. 41:932-933
A crosslinked poly(allylamine) was prepared by copolymerization of allylammonium dihydrogen phosphate with N,N′-diallyl-1,3-diaminopropane bis(dihydrogen phosphate). This polymer has both a high ph...
Publikováno v:
J. Chem. Soc., Chem. Commun.. :63-64
(±)-Helminthosporal has been synthesized starting from a bicyclo[3.2.1]oct-1-en-2,8-dione which is produced on electrolysis of 3,4-dimethoxy-6-methylphenol in the presence of an excess of (E)-isoeugenol methyl ether.
Publikováno v:
Chemistry Letters; 9/5/2012, Vol. 41 Issue 9, p932-933, 2p