Výsledky vyhledávání - "Kazufumi Iwata"

Effects of genetic variants in SLC22A2 organic cation transporter 2 and SLC47A1 multidrug and toxin extrusion 1 transporter on cisplatin-induced adverse events

Autor: Minoru Yoshida, Eiko Fukunaga, Misato Yoshimura, Sachiko Jingami, Keiji Aizawa, Akinobu Hamada, Kazufumi Iwata, Hideyuki Saito, Saori Kamitsu

Publikováno v: Clinical and Experimental Nephrology. 16:843-851

Susceptibility to cisplatin (CDDP) nephrotoxicity is known to vary between individuals, but the basis of this variation has not been fully elucidated. In the kidney, CDDP is taken up into the renal proximal tubular cells mainly via SLC22A2 organic ca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f30d3c720f4fbda1c7befc88af3adf08
https://doi.org/10.1007/s10157-012-0638-y

Zobrazit plný text záznamu

Regulation of Renal Organic Ion Transporters in Cisplatin-Induced Acute Kidney Injury and Uremia in Rats

Autor: Masahiro Kusumoto, Takafumi Morisaki, Koji Yokoo, Kazufumi Iwata, Hideyuki Saito, Takanobu Matsuzaki, Akinobu Hamada

Publikováno v: Pharmaceutical Research. 25:2526-2533

Purpose The purpose of this study was to examine the regulation of renal organic ion transporters in cisplatin-induced acute kidney injury (AKI) and its relation with indoxyl sulfate (IS), a uremic toxin. Methods The IS concentrations in the serum an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9b3edb896af6847a3d6bc2e0ae9599d
https://doi.org/10.1007/s11095-008-9668-2

Zobrazit plný text záznamu

Involvement of Indoxyl Sulfate in Renal and Central Nervous System Toxicities During Cisplatin-induced Acute Renal Failure

Autor: Akinobu Hamada, Takafumi Morisaki, Kazufumi Iwata, Hideyuki Saito, Takanobu Matsuzaki, Takafumi Ohmura, Hiroshi Watanabe

Publikováno v: Pharmaceutical Research. 24:662-671

The purpose of the present study was to explore the involvement of indoxyl sulfate (IS) in nephrotoxicity and central nervous system (CNS) toxicity in cisplatin (CDDP)-treated rats. Renal function was evaluated by serum creatinine and BUN levels. The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8cb5ba917ae573a7bddd3c258db88d2
https://doi.org/10.1007/s11095-006-9183-2

Zobrazit plný text záznamu

Possible false-negative results on therapeutic drug monitoring of phenytoin using a particle enhanced turbidimetric inhibition immunoassay in a patient with a high level of IgM

Autor: Yuhuki Enoki, Toru Maruyama, Eiko Fukunaga, Junji Saruwatari, Yu Ishima, Kazufumi Iwata, Kentaro Ueda, Daisuke Kadowaki, Hiroshi Watanabe, Takumi Shirouzono, Yukino Urata, Hiroshi Moriuchi, Motoki Imamura, Keiji Aizawa, Sumio Hirata, Kenshiro Hirata

Publikováno v: Therapeutic drug monitoring. 36(5)

In this report, the authors described the unusual case of a patient in whom the plasma phenytoin concentration was unexpectedly not detected on a particle-enhanced turbidimetric inhibition immunoassay (PETINIA) technique, a typical immunoassay for ph

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b9cb56db95c98f54fb3ee68107e033b
https://pubmed.ncbi.nlm.nih.gov/25478903

Zobrazit plný text záznamu