Preventive Effects of Pentoxifylline on the Development of Colonic Premalignant Lesions in Obese and Diabetic Mice

Autor: Kazufumi Fukuta, Yohei Shirakami, Akinori Maruta, Koki Obara, Soichi Iritani, Nobuhiko Nakamura, Takahiro Kochi, Masaya Kubota, Hiroyasu Sakai, Takuji Tanaka, Masahito Shimizu

Publikováno v: International Journal of Molecular Sciences, Vol 18, Iss 2, p 413 (2017)

Obesity and its related metabolic abnormalities, including enhanced oxidative stress and chronic inflammation, are closely related to colorectal tumorigenesis. Pentoxifylline (PTX), a methylxanthine derivative, has been reported to suppress the produ

Externí odkaz: https://doaj.org/article/cb5c71c014284dc1b50bb6d5e86ea772

Preventive Effects of Pentoxifylline on the Development of Colonic Premalignant Lesions in Obese and Diabetic Mice

Autor: Soichi Iritani, Takahiro Kochi, Yohei Shirakami, Masaya Kubota, Koki Obara, Akinori Maruta, Kazufumi Fukuta, Hiroyasu Sakai, Masahito Shimizu, Takuji Tanaka, Nobuhiko Nakamura

Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 18, Iss 2, p 413 (2017)
International Journal of Molecular Sciences; Volume 18; Issue 2; Pages: 413

Obesity and its related metabolic abnormalities, including enhanced oxidative stress and chronic inflammation, are closely related to colorectal tumorigenesis. Pentoxifylline (PTX), a methylxanthine derivative, has been reported to suppress the produ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7a59cea6d60927c313219f332140f2c
https://pubmed.ncbi.nlm.nih.gov/28212276