Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Kazue Edaki"'
Autor:
Xieyi Zhang, Wangyang Liu, Kazue Edaki, Yuta Nakazawa, Saori Takahashi, Hiroki Sunakawa, Kenta Mizoi, Takuo Ogihara
Publikováno v:
Biomolecules, Vol 12, Iss 6, p 806 (2022)
Transcriptional factors, such as Snail, Slug, and Smuc, that cause epithelial-mesenchymal transition are thought to regulate the expression of Ezrin, Radixin, and Moesin (ERM proteins), which serve as anchors for efflux transporters on the plasma mem
Externí odkaz:
https://doaj.org/article/a4a1b3bb298f40b18e7b3a2e2217690e
Autor:
Xieyi Zhang, Wangyang Liu, Kazue Edaki, Yuta Nakazawa, Hiroki Kamioka, Atsushi Fujita, Ryoichi Onozato, Misa Iijima, Shigeru Tsuchida, Takahiro Arai, Yukiyoshi Fujita, Kenta Mizoi, Takuo Ogihara
Publikováno v:
Canadian Journal of Infectious Diseases and Medical Microbiology, Vol 2021 (2021)
Multidrug resistance (MDR) due to enhanced drug efflux activity of tumor cells can severely impact the efficacy of antitumor therapies. We recently showed that increased activity of the efflux transporter P-glycoprotein (P-gp) associated with activat
Externí odkaz:
https://doaj.org/article/69d15ea92e944128a255dbaa3e7dfa6b
Publikováno v:
Journal of Pharmacy and Pharmacology. 73:1609-1616
Objectives Epithelial–mesenchymal transition (EMT) plays a role in cancer metastasis as well as in drug resistance through various mechanisms, including increased drug efflux mediated by P-glycoprotein (P-gp). In this study, we investigated the act