Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Kazue, Gonda"'
Autor:
Tomohiko Sakabe, Hiroyuki Tsuchiya, Keita Kanki, Junya Azumi, Kazue Gonda, Yusuke Mizuta, Daisaku Yamada, Hiroshi Wada, Kohei Shomori, Hiroaki Nagano, Goshi Shiota
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56197 (2013)
The incidence of advanced hepatocellular carcinoma (HCC) is increasing worldwide, and its prognosis is extremely poor. Interferon-alpha (IFN-α)/5-fluorouracil (5-FU) therapy is reportedly effective in some HCC patients. In the present study, to impr
Externí odkaz:
https://doaj.org/article/7fca056d4adf4ef89e7105ea1bb9e074
Autor:
Kazue Gonda, Kei Terabayashi, Yuji Akechi, Kazuko Takubo, Remina Ikeda, Yoshiko Hoshikawa, Goshi Shiota, Akihiro Umezawa, Yoshiaki Matsumi, Akihiro Kurimasa, Hiroyuki Tsuchiya, Hideharu Okamoto, Ren Nishio, Kyoko Ishii, Yoko Yoshida, Fumihito Tajima, Tomohiko Sakabe
Publikováno v:
Hepatology. 48:597-606
Human bone marrow–derived mesenchymal stem cells (BM-MSCs) are expected to be a potential source of cells for transplantation. Although recent reports have shown that isolated MSCs can differentiate into hepatocytes, the efficiency of differentiati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a68db63932a4eb2f57fe3c385bbd7360
https://doi.org/10.1002/hep.22362
https://doi.org/10.1002/hep.22362
Autor:
Ichiro Hisatome, Taro Uyama, Tomohiko Sakabe, Kazue Gonda, Yumi Watanabe, Goshi Shiota, Yoko Yoshida, Hiroyuki Tsuchiya, Saori Matsuoka, Masanori Terai, Akihiro Umezawa, Kazuko Takubo, Akihiro Kurimasa, Yoshiko Hoshikawa, Kyoko Ishii, Takashi Shimomura
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 293:G1089-G1098
Human umbilical cord blood-derived mesenchymal stem cells (UCBMSCs) are expected to be an excellent source of cells for transplantation. In addition, the stem cell plasticity of human UCBMSCs, which can transdifferentiate into hepatocytes, has been r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4fe82f4de5b19ac33a05178cc9f42e0
https://doi.org/10.1152/ajpgi.00187.2007
https://doi.org/10.1152/ajpgi.00187.2007
Autor:
Kohei Shomori, Yusuke Mizuta, Tomohiko Sakabe, Kazue Gonda, Hiroshi Wada, Hiroyuki Tsuchiya, Junya Azumi, Goshi Shiota, Hiroaki Nagano, Keita Kanki, Daisaku Yamada
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 2, p e56197 (2013)
PLoS ONE, Vol 8, Iss 2, p e56197 (2013)
The incidence of advanced hepatocellular carcinoma (HCC) is increasing worldwide, and its prognosis is extremely poor. Interferon-alpha (IFN-α)/5-fluorouracil (5-FU) therapy is reportedly effective in some HCC patients. In the present study, to impr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b30a1861a45b44e7a11a18a08bf56e9b
http://europepmc.org/articles/PMC3574150
http://europepmc.org/articles/PMC3574150
Autor:
Yoshiko Hoshikawa, Kazue Gonda, Kei Terabayashi, Naoki Terakawa, An Afida Ashla, Hiroaki Itamochi, Tasuku Harada, Ren Nishio, Hiroyuki Tsuchiya, Saori Matsuoka, Akihiro Kurimasa, Goshi Shiota, Yuka Fujimoto, Kyoko Ishii, Akiko Tomita, Hideharu Okamoto, Yumi Watanabe, Keitaro Yamane, Tomohiko Sakabe, Yoshiaki Matsumi, Kazuko Takubo, Remina Ikeda, Yuji Akechi
Publikováno v:
Biochemical and biophysical research communications. 366(3)
A synthetic retinoid, CD437, has been shown to exert potent anti-tumor activity against various types of cancer cell lines, regardless of their sensitivities to natural retinoids. We herein demonstrate that CD437 induces endoplasmic reticulum (ER) st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f06d32c778a930456902a973a8ee150
https://pubmed.ncbi.nlm.nih.gov/18082618
https://pubmed.ncbi.nlm.nih.gov/18082618
Autor:
Miho, Ichiba, Sadako, Yamada, Kyoko, Ishii, Kazue, Gonda, Rie, Murai, Takashi, Shimomura, Toshiya, Saeki, Takamasa, Kanbe, Yoshitada, Tanabe, Yoko, Yoshida, Hiroyuki, Tsuchiya, Yoshiko, Hoshikawa, Akihiro, Kurimasa, Yukihiro, Kishimoto, Hironaka, Kawasaki, Goshi, Shiota
Publikováno v:
Hepato-gastroenterology. 54(78)
Although the importance of reactive oxygen species (ROS) in the pathogenesis of various diseases is stressed, clinical significance of the markers reflecting DNA oxidation such as 8-hydroxy-2'-deoxyguanosine (8-OHdG) remains to be clarified.To examin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9a6103f858b98744561e9bae1ae0939a
https://pubmed.ncbi.nlm.nih.gov/18019707
https://pubmed.ncbi.nlm.nih.gov/18019707
Autor:
Tomohiko Sakabe, Ichiro Hisatome, Taro Uyama, Rie Murai, Kazue Gonda, Goshi Shiota, Kazuko Takubo, Takashi Shimomura, Akihiro Umezawa, Kyoko Ishii, Akihiro Kurimasa, Yoshiko Hoshikawa, Hiroyuki Tsuchiya, Yoko Yoshida
Publikováno v:
Hepatology research : the official journal of the Japan Society of Hepatology. 37(12)
AIM Bone marrow-derived mesenchymal stem cells (MSC) are expected to be an excellent source of cells for transplantation. We aimed to study the culture conditions and involved genes to differentiate MSC into hepatocytes. METHODS The culture condition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dca5a72b60cb98e8548adc94aa98a3d2
https://pubmed.ncbi.nlm.nih.gov/17627621
https://pubmed.ncbi.nlm.nih.gov/17627621
Autor:
Hiroyuki, Kato, Takashi, Shimomura, Rie, Murai, Kazue, Gonda, Kyoko, Ishii, Yoko, Yoshida, Takamasa, Kanbe, Ko-ichi, Hashiguchi, Tomohiko, Sakabe, Kazue, Takubo, Jun-ichi, Okano, Hiroyuki, Tsuchiya, Yoshiko, Hoshikawa, Akihiro, Kurimasa, Goshi, Shiota
Publikováno v:
Hepato-gastroenterology. 54(75)
To rescue patients with severe liver injury, it is critical to develop the efficient regulatory system of hepatic stem cell proliferation in vitro. Our aims are to examine whether combination of adenovirus-mediated hepatocyte growth factor (HGF) gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9751b90a97991fd8cf31ec0b6c7c33b0
https://pubmed.ncbi.nlm.nih.gov/17591071
https://pubmed.ncbi.nlm.nih.gov/17591071
Autor:
Yoshiko Hoshikawa, Kazue Gonda, Kyoko Ishii, Goshi Shiota, Shingo Yanagida, Hiroyuki Tsuchiya, Akiko Tomita, Naoto Ishibashi, Michiko Endo, Tomohiko Sakabe, Rie Murai, Kazuko Takubo, Akihiro Kurimasa
Publikováno v:
Biochemical pharmacology. 73(9)
The mechanisms of prevention of the development of liver cancer by NIK-333, an acyclic retinoid (ACR), were investigated. The transgenic mice expressing the dominant negative form of retinoic acid receptor alpha (RARE mice), that produce reactive oxy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4be773ff9dd98ff1f0bd8a2b107e38f7
https://pubmed.ncbi.nlm.nih.gov/17261273
https://pubmed.ncbi.nlm.nih.gov/17261273