Zobrazeno 1 - 10
of 631
pro vyhledávání: '"Kazuaki Shimamoto"'
Autor:
Marenao Tanaka, Satoko Takahashi, Yukimura Higashiura, Akiko Sakai, Masayuki Koyama, Shigeyuki Saitoh, Kazuaki Shimamoto, Hirofumi Ohnishi, Masato Furuhashi
Publikováno v:
Journal of Diabetes Investigation, Vol 13, Iss 5, Pp 878-888 (2022)
ABSTRACT Aims/Introduction Metabolic dysfunction‐associated fatty liver disease (MAFLD), defined as hepatosteatosis with type 2 diabetes mellitus, overweight/obesity or metabolic dysregulation, has been proposed as a new feature of chronic liver di
Externí odkaz:
https://doaj.org/article/9d32630c1daa4baabd03a63fcfb8afe3
Autor:
Norie Saito, Masato Furuhashi, Masayuki Koyama, Yukimura Higashiura, Hiroshi Akasaka, Marenao Tanaka, Norihito Moniwa, Hirofumi Ohnishi, Shigeyuki Saitoh, Nobuyuki Ura, Kazuaki Shimamoto, Tetsuji Miura
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Fatty acid-binding protein 4 (FABP4) is secreted from adipose tissue and acts as an adipokine, and an elevated circulating FABP4 level is associated with metabolic disorders and atherosclerosis. However, little is known about the causal link
Externí odkaz:
https://doaj.org/article/a1b163a29f68452081605024bd37debd
Autor:
Masato Furuhashi, Masayuki Koyama, Yukimura Higashiura, Takayo Murase, Takashi Nakamura, Megumi Matsumoto, Akiko Sakai, Hirofumi Ohnishi, Marenao Tanaka, Shigeyuki Saitoh, Norihito Moniwa, Kazuaki Shimamoto, Tetsuji Miura
Publikováno v:
Journal of Diabetes Investigation, Vol 11, Iss 4, Pp 878-887 (2020)
Abstract Aims/Introduction Uric acid is synthesized by oxidation of hypoxanthine and xanthine using a catalyzing enzyme, xanthine oxidoreductase (XOR), which can be a source of reactive oxygen species. Plasma XOR activity is a metabolic biomarker ass
Externí odkaz:
https://doaj.org/article/58fedaa48bff4b9c9d0b3b4a701c113b
Autor:
Hiroyasu Iso, Renzhe Cui, Iseki Takamoto, Masahiko Kiyama, Isao Saito, Tomonori Okamura, Yoshihiro Miyamoto, Aya Higashiyama, Yutaka Kiyohara, Toshiharu Ninomiya, Michiko Yamada, Hideaki Nakagawa, Masaru Sakurai, Michio Shimabukuro, Moritake Higa, Kazuaki Shimamoto, Shigeyuki Saito, Makoto Daimon, Takamasa Kayama, Mitsuhiko Noda, Sadayoshi Ito, Koutaro Yokote, Chikako Ito, Kazuwa Nakao, Toshimasa Yamauchi, Takashi Kadowaki
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 23 (2021)
Background It is uncertain whether risk classification under the nationwide program on screening and lifestyle modification for metabolic syndrome captures well high‐risk individuals who could benefit from lifestyle interventions. We examined the v
Externí odkaz:
https://doaj.org/article/1072e28ce9a34ac28fe7c82d7a2ebd72
Autor:
Masato Furuhashi, Megumi Matsumoto, Takayo Murase, Takashi Nakamura, Yukimura Higashiura, Masayuki Koyama, Marenao Tanaka, Norihito Moniwa, Hirofumi Ohnishi, Shigeyuki Saitoh, Kazuaki Shimamoto, Tetsuji Miura
Publikováno v:
Journal of Diabetes Investigation, Vol 10, Iss 4, Pp 1059-1067 (2019)
Abstract Aims/Introduction Xanthine oxidoreductase (XOR) is a rate‐limiting enzyme that catalyzes uric acid formation in the purine metabolism, is involved in an increase in reactive oxygen species. Plasma XOR activity has been shown to be associat
Externí odkaz:
https://doaj.org/article/402248b2974f49619910c057e685e285
Autor:
Masato Furuhashi, Yukimura Higashiura, Akiko Sakai, Masayuki Koyama, Marenao Tanaka, Shigeyuki Saitoh, Kazuaki Shimamoto, Hirofumi Ohnishi
Publikováno v:
Metabolites, Vol 12, Iss 3, p 237 (2022)
Tsukushi (TSK) is a member of the small leucine-rich proteoglycan family that controls developmental processes and organogenesis. TSK was also identified as a new hepatokine, which is mainly expressed in the liver, and is secreted by hepatocytes, to
Externí odkaz:
https://doaj.org/article/91a826a8f7e64776bdbf323d010752a7
Autor:
Masato Furuhashi, Masatsune Ogura, Megumi Matsumoto, Satoshi Yuda, Atsuko Muranaka, Mina Kawamukai, Akina Omori, Marenao Tanaka, Norihito Moniwa, Hirofumi Ohnishi, Shigeyuki Saitoh, Mariko Harada-Shiba, Kazuaki Shimamoto, Tetsuji Miura
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract Cholesterol efflux capacity (CEC) from macrophages, the first step in the reverse cholesterol transport pathway, is inversely associated with residual risk for atherosclerotic cardiovascular disease. Fatty acid-binding protein 4 (FABP4) and
Externí odkaz:
https://doaj.org/article/f7e78848e7db4a6992e2d980ee8c9716
Autor:
Haruno Nishimuro, Hirofumi Ohnishi, Midori Sato, Mayumi Ohnishi-Kameyama, Izumi Matsunaga, Shigehiro Naito, Katsunari Ippoushi, Hideaki Oike, Tadahiro Nagata, Hiroshi Akasaka, Shigeyuki Saitoh, Kazuaki Shimamoto, Masuko Kobori
Publikováno v:
Nutrients, Vol 7, Iss 4, Pp 2345-2358 (2015)
Quercetin is a promising food component, which can prevent lifestyle related diseases. To understand the dietary intake of quercetin in the subjects of a population-based cohort study and in the Japanese population, we first determined the quercetin
Externí odkaz:
https://doaj.org/article/4106769f5c6241489a0ec5ecffcb33fe
Publikováno v:
Clinical Medicine Insights: Cardiology, Vol 2014, Iss Suppl. 3, Pp 23-33 (2015)
Externí odkaz:
https://doaj.org/article/fc5003e44b9c4ccdafec88094e6a9a60
Autor:
Ilana Cruz-Silva, Viviane Abreu Nunes, Andrezza Justino Gozzo, Priscila Praxedes-Garcia, Aparecida Sadae Tanaka, Kazuaki Shimamoto, Mariana Silva Araujo
Publikováno v:
Pulmonary Medicine, Vol 2016 (2016)
Inflammation is an essential process in many pulmonary diseases in which kinins are generated by protease action on kininogen, a phenomenon that is blocked by protease inhibitors. We evaluated kinin release in an in vivo lung inflammation model in ra
Externí odkaz:
https://doaj.org/article/3b0fbb1dc5e64f8e88b29d5ffc05bfed