Zobrazeno 1 - 10
of 566
pro vyhledávání: '"Kazuaki, Takabe"'
Autor:
Jessica Young, Pawel Kalinski, Mateusz Opyrchal, Kathleen M Kokolus, Sacha Gnjatic, Jianming Wang, Shipra Gandhi, Kristopher Attwood, Tracey O’Connor, Kazuaki Takabe, Victoria Fitzpatrick, Eduardo Cortes Gomez, Stephen Edge, Janine Miller, Ronald T Slomba, Ellis G Levine, Sinem Ozbey, Giorgio Ioannou, Cayla Janes, Igor De Souza, Vladimir Roudko, Prasanna Kumar, Suresh Kalathil, Helen Cappuccino
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 11 (2024)
Background Higher cytotoxic T lymphocyte (CTL) numbers in the tumor microenvironment (TME) predict pathologic complete response (pCR) to neoadjuvant chemotherapy (NAC) and positive long-term outcomes in triple-negative breast cancer (TNBC). pCR to NA
Externí odkaz:
https://doaj.org/article/d569717b5be14a588e378c08cde71fa3
Autor:
Jeffrey C. Martin, Tatiane da Silva Fernandes, Kanita A. Chaudhry, Masanori Oshi, Scott I. Abrams, Kazuaki Takabe, Spencer R. Rosario, Anna Bianchi-Smiraglia
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Triple-negative breast cancer (TNBC) is one of the most aggressive types of cancer. Despite decades of intense investigation, treatment options remain limited, and rapid recurrence with distant metastases remains a significant challenge. Can
Externí odkaz:
https://doaj.org/article/a7c14905d0a540b290c52c0f37711b58
Autor:
Masanori Oshi, Shipra Gandhi, Rongrong Wu, Mariko Asaoka, Li Yan, Akimitsu Yamada, Shinya Yamamoto, Kazutaka Narui, Takashi Chishima, Takashi Ishikawa, Itaru Endo, Kazuaki Takabe
Publikováno v:
Biomarker Research, Vol 10, Iss 1, Pp 1-11 (2022)
Abstract Background BRCAness is a characteristic feature of homologous recombination deficiency (HRD) mimicking BRCA gene mutation in breast cancer. We hypothesized that a measure to quantify BRCAness that causes synthetic lethality in BRCA mutated t
Externí odkaz:
https://doaj.org/article/5017b9300635441caab79d7ab54c3fe7
Autor:
Yara Abdou, Medhavi Gupta, Mariko Asaoka, Kristopher Attwood, Opyrchal Mateusz, Shipra Gandhi, Kazuaki Takabe
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Breast cancer is more common on the left side than the right side. We aim to evaluate differences in clinicopathological and genomic characteristics based on laterality. We analyzed survival outcomes and clinical characteristics of 881,320 p
Externí odkaz:
https://doaj.org/article/b3eb4210066c4d778fbd0ef179581fe6
Autor:
Masanori Oshi, Ankit Patel, Rongrong Wu, Lan Le, Yoshihisa Tokumaru, Akimitsu Yamada, Li Yan, Ryusei Matsuyama, Takashi Ishikawa, Itaru Endo, Kazuaki Takabe
Publikováno v:
npj Breast Cancer, Vol 8, Iss 1, Pp 1-10 (2022)
Abstract Although the value of tumor-infiltrating lymphocytes is well known, the clinical relevance of an increased immune response, specifically in breast cancer, has not been investigated across large cohorts of patients using computational algorit
Externí odkaz:
https://doaj.org/article/eaa72d2a8b7f490789450bdca11f1b29
Publikováno v:
Surgery in Practice and Science, Vol 13, Iss , Pp 100162- (2023)
Workplace related burnout is rampant in medicine. Prevalence is even higher in surgical specialties, higher during various stages of training, and higher still in females in these specialties. There has been a concerted effort by various deliberative
Externí odkaz:
https://doaj.org/article/c1eccada648e4ba9b11bafc1f222a585
Autor:
Masanori Oshi, Rongrong Wu, Thaer Khoury, Shipra Gandhi, Li Yan, Akimitsu Yamada, Takashi Ishikawa, Itaru Endo, Kazuaki Takabe
Publikováno v:
Annals of Surgery; Oct2024, Vol. 280 Issue 4, p557-569, 13p
Autor:
Ya Wang, Long Qiao, Jie Yang, Xiong Li, Yaqi Duan, Jiahao Liu, Shaoqi Chen, Huayi Li, Dan Liu, Tian Fang, Jingjing Ma, Xiaoting Li, Fei Ye, Junxiang Wan, Juncheng Wei, Qin Xu, Ensong Guo, Ping Jin, Mingfu Wu, Lin Zhang, Yun Xia, Yaqun Wu, Jun Shao, Yaojun Feng, Qing Zhang, Zongyuan Yang, Gang Chen, Qinghua Zhang, Xingrui Li, Shixuan Wang, Junbo Hu, Xiaoyun Wang, Mona P. Tan, Kazuaki Takabe, Beihua Kong, Qifeng Yang, Ding Ma, Qinglei Gao
Publikováno v:
Cancer Communications, Vol 41, Iss 12, Pp 1373-1386 (2021)
Abstract Background To date, there is no approved blood‐based biomarker for breast cancer detection. Herein, we aimed to assess semaphorin 4C (SEMA4C), a pivotal protein involved in breast cancer progression, as a serum diagnostic biomarker. Method
Externí odkaz:
https://doaj.org/article/4e35427d50514982972a9b3fc4530215
Low expression of miR-29a is associated with aggressive biology and worse survival in gastric cancer
Autor:
Yoshihisa Tokumaru, Masanori Oshi, Michelle R. Huyser, Li Yan, Masahiro Fukada, Nobuhisa Matsuhashi, Manabu Futamura, Yukihiro Akao, Kazuhiro Yoshida, Kazuaki Takabe
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Advanced gastric cancer (GC) is one of the most lethal cancer types, thus a better understanding of its biology in patients is urgently needed. MicroRNA (miR)-29a is a known tumor suppressive miR that is related to metastasis, but its clinic
Externí odkaz:
https://doaj.org/article/2e78e900ae834d0e990a3b64daadad1c
Autor:
Masanori Oshi, Yoshihisa Tokumaru, Fernando A. Angarita, Lan Lee, Li Yan, Ryusei Matsuyama, Itaru Endo, Kazuaki Takabe
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Cancer-associated adipocytes are known to cause inflammation; however, the role of adipogenesis, the formation of adipocytes, in breast cancer is unclear. We hypothesized that intra-tumoral adipogenesis reflects a different cancer biology th
Externí odkaz:
https://doaj.org/article/8e8e578ee3e7418aa94b0630ea1d77e0