Zobrazeno 1 - 10
of 128
pro vyhledávání: '"Kazim Yalcin Arga"'
Publikováno v:
Biomarker Insights, Vol 19 (2024)
Background: Clinical biomarkers, allow better classification of patients according to their disease risk, prognosis, and/or response to treatment. Although affordable omics-based approaches have paved the way for quicker identification of putative bi
Externí odkaz:
https://doaj.org/article/243bcd9b3785462795897023817af81f
Publikováno v:
Cancer Medicine, Vol 12, Iss 24, Pp 22420-22436 (2023)
Abstract Acute myeloid leukemia (AML) is a heterogeneous disease and the most common form of acute leukemia with a poor prognosis. Due to its complexity, the disease requires the identification of biomarkers for reliable prognosis. To identify potent
Externí odkaz:
https://doaj.org/article/b60eb5f52de543cc838a716485ef6795
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/3d94d29769a446d0ad69614ba9f2decf
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionIntegrating interaction data with biological knowledge can be a critical approach for drug development or drug repurposing. In this context, host-pathogen-protein-protein interaction (HP-PPI) networks are useful instrument to uncover the
Externí odkaz:
https://doaj.org/article/abe358bd43ba4c3aa3ffbfa063a62e77
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Cervical cancer is the fourth most commonly diagnosed cancer worldwide and, in almost all cases is caused by infection with highly oncogenic Human Papillomaviruses (HPVs). On the other hand, inflammation is one of the hallmarks of cancer research. He
Externí odkaz:
https://doaj.org/article/d6031e116f1b4cc091301f22b6c0378e
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Abstract PEA3 transcription factor subfamily is present in a variety of tissues with branching morphogenesis, and play a particularly significant role in neural circuit formation and specificity. Many target genes in axon guidance and cell–cell adh
Externí odkaz:
https://doaj.org/article/5cd4e432943d4296a30c5983d38501ef
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Abstract Deciphering the variations in the protein interactome is required to reach a systems-level understanding of tumorigenesis. To accomplish this task, we have considered the clinical and transcriptome data on >6000 samples from The Cancer Genom
Externí odkaz:
https://doaj.org/article/912502fff7a2467d9c8cd21444eecd50
Autor:
Hande Beklen, Sema Arslan, Gizem Gulfidan, Beste Turanli, Pemra Ozbek, Betul Karademir Yilmaz, Kazim Yalcin Arga
Publikováno v:
Frontiers in Bioinformatics, Vol 1 (2021)
There is a critical requirement for alternative strategies to provide the better treatment in colorectal cancer (CRC). Hence, our goal was to propose novel biomarkers as well as drug candidates for its treatment through differential interactome based
Externí odkaz:
https://doaj.org/article/2999ef6b66e3445bafd3e487c38a5771
Autor:
Beste Turanli, Cheng Zhang, Woonghee Kim, Rui Benfeitas, Mathias Uhlen, Kazim Yalcin Arga, Adil Mardinoglu
Publikováno v:
EBioMedicine, Vol 42, Iss , Pp 386-396 (2019)
Background: Genome-scale metabolic models (GEMs) offer insights into cancer metabolism and have been used to identify potential biomarkers and drug targets. Drug repositioning is a time- and cost-effective method of drug discovery that can be applied
Externí odkaz:
https://doaj.org/article/9cf566f76b6448b196142f1d5b3f9f34
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Colorectal cancer (CRC) is one of the most fatal types of cancers that is seen in both men and women. CRC is the third most common type of cancer worldwide. Over the years, several drugs are developed for the treatment of CRC; however, patients with
Externí odkaz:
https://doaj.org/article/7fc054b5ff724f70ae33376c46be2be1