Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Kazi Mirajul, Hoque"'
Autor:
Tultul Saha, Joydeep Aoun, Paramita Sarkar, Andrea J. Bourdelais, Daniel G. Baden, Normand Leblanc, John M. Hamlyn, Owen M. Woodward, Kazi Mirajul Hoque
Publikováno v:
Pharmaceutical Biology, Vol 59, Iss 1, Pp 1008-1015 (2021)
Context Cucumber (Cucumis sativus Linn. [Cucurbitaceae]) is widely known for its purgative, antidiabetic, antioxidant, and anticancer therapeutic potential. However, its effect on gastrointestinal (GI) disease is unrecognised. Objective This study in
Externí odkaz:
https://doaj.org/article/4d4c56a7fd524cb48851e0eb97bd40fa
Autor:
Kazi Mirajul Hoque, Eryn E. Dixon, Raychel M. Lewis, Jordyn Allan, Gregory D. Gamble, Amanda J. Phipps-Green, Victoria L. Halperin Kuhns, Anne M. Horne, Lisa K. Stamp, Tony R. Merriman, Nicola Dalbeth, Owen M. Woodward
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
The common ABCG2 variant Q141K contributes to hyperuricemia and gout risk. Here, using a human interventional study and a new orthologous mouse model, the authors report a tissue specific pathobiology of the Q141K variant, and support a significant r
Externí odkaz:
https://doaj.org/article/12c73f6333324432b9f2c84850631506
Autor:
Tultul Saha, Joydeep Aoun, Mikio Hayashi, Sheikh Irshad Ali, Paramita Sarkar, Prasanta Kumar Bag, Normand Leblanc, Nadia Ameen, Owen M. Woodward, Kazi Mirajul Hoque
Publikováno v:
Biochemistry and Biophysics Reports, Vol 25, Iss , Pp 100912- (2021)
TMEM16A (Transmembrane protein 16A or Anoctamin1) is a calcium-activated chloride channel.(CaCC),that exerts critical roles in epithelial secretion. However, its localization, function, and regulation in intestinal chloride (Cl−) secretion remain o
Externí odkaz:
https://doaj.org/article/e21626b8bb1f4a1d99010739096d5722
Autor:
Karl Kunzelmann, Raquel Centeio, Podchanart Wanitchakool, Inês Cabrita, Roberta Benedetto, Tultul Saha, Kazi Mirajul Hoque, Rainer Schreiber
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Cl– secretion by the human and murine intestinal epithelium occurs through the cystic fibrosis transmembrane conductance regulator (cftr). However, the Ca2+ activated Cl– channel Tmem16a was shown to contribute to Cl– secretion, mainly, but not
Externí odkaz:
https://doaj.org/article/53df0f54cae54fc9ba59bfeea3e28ec3
Autor:
Swapan Kumar Jana, Pinak Chakrabarti, Kazi Mirajul Hoque, Anup Kumar Misra, Arin Gucchait, Somobrata Acharya, Tultul Saha, Susmita Paul, Barun K. Chatterjee, Tanaya Chatterjee
Publikováno v:
ACS Applied Bio Materials. 4:3089-3100
Because of the emergence of multidrug-resistant pathogenic bacteria, there is a growing interest for the development of an efficient alternative to antibiotics. Gold nanoparticles (AuNPs) are promi...
Autor:
Swapan Kumar, Jana, Arin, Gucchait, Susmita, Paul, Tultul, Saha, Somobrata, Acharya, Kazi Mirajul, Hoque, Anup Kumar, Misra, Barun K, Chatterjee, Tanaya, Chatterjee, Pinak, Chakrabarti
Publikováno v:
ACS applied bio materials. 4(4)
Because of the emergence of multidrug-resistant pathogenic bacteria, there is a growing interest for the development of an efficient alternative to antibiotics. Gold nanoparticles (AuNPs) are promising candidates due to their inherent non-toxicity an
Autor:
Kazi Mirajul Hoque, Leandra Kali Figueroa‐Hall, TuKiet T. Lam, Rolando Garcia-Milian, Vanessa M Baratta, Pedro J.I. Salas, Kaimul Ahsan, Nadia A. Ameen
Publikováno v:
Am J Physiol Gastrointest Liver Physiol
Nongenomic glucocorticoid (GC) and serum- and glucocorticoid-inducible kinase 1 (SGK1) signaling regulate ion transport, but CFTR has not been investigated in the intestine. We examined GC, SGK1, and phosphatidylinositol 3-kinase (PI3K) kinase signal
Autor:
Tony R. Merriman, Raychel M. Lewis, Owen M. Woodward, Gregory D. Gamble, Anne Horne, Lisa K. Stamp, Eryn E. Dixon, Nicola Dalbeth, Amanda Phipps-Green, Kazi Mirajul Hoque, Jordyn Allan, Victoria L. Halperin Kuhns
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
The pathophysiological nature of the common ABCG2 gout and hyperuricemia associated variant Q141K (rs2231142) remains undefined. Here, we use a human interventional cohort study (ACTRN12615001302549) to understand the physiological role of ABCG2 and
Autor:
Tanaya Chatterjee, Irshad Ali Sheikh, Devlina Chakravarty, Pinak Chakrabarti, Paramita Sarkar, Tultul Saha, Manoj K Chakrabarti, Kazi Mirajul Hoque
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0141283 (2015)
Cholera pathogenesis occurs due to synergistic pro-secretory effects of several toxins, such as cholera toxin (CTX) and Accessory cholera enterotoxin (Ace) secreted by Vibrio cholerae strains. Ace activates chloride channels stimulating chloride/bica
Externí odkaz:
https://doaj.org/article/de1d53e0d9514c72899482cba0d24933
Autor:
Kazi Mirajul Hoque, Paramita Sarkar, Pinak Chakrabarti, Barun K. Chatterjee, Tanaya Chatterjee, Tultul Saha
Publikováno v:
Colloids and surfaces. B, Biointerfaces. 204
Formation of biofilm by Vibrio cholerae plays a crucial role in pathogenesis and transmission of cholera. Lower infective dose of the biofilm form of V. cholerae compared to the planktonic counterpart, and its antibiotic resistance, make it challengi