Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Kazi Amirul, Hossain"'
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 2526-2536 (2021)
Because of high stability and slow unfolding rates of G-quadruplexes (G4), cells have evolved specialized helicases that disrupt these non-canonical DNA and RNA structures in an ATP-dependent manner. One example is DHX36, a DEAH-box helicase, which p
Externí odkaz:
https://doaj.org/article/d2352cb5bece421bb065553b83cc5d1d
Publikováno v:
The Journal of Physical Chemistry Letters
Fo subcomplex of ATP synthase is an membraneembedded rotary motor that converts proton motive force into mechanical energy. Despite a rapid increase in the number of high-resolution structures, the mechanism of tight coupling between proton transport
Autor:
Kazi Amirul Hossain, Mateusz Kogut, Joanna Słabońska, Subrahmanyam Sappati, Miłosz Wieczór, Jacek Czub
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Despite the negative charge of the DNA backbone, acidic residues (Asp/Glu) commonly participate in the base readout, with a strong preference for cytosine. In fact, in the solved DNA/protein structures, cytosine is recognized almost exclusively by As
Autor:
Gangireddy Sujeevan, Reddy, Sharda, Shukla, Harshavardhan, Bhuktar, Kazi Amirul, Hossain, Rebecca Kristina, Edwin, Varadaraj Bhat, Giliyaru, Parimal, Misra, Manojit, Pal
Publikováno v:
RSC advances. 12(41)
In view of the reported chorismate mutase (CM or
Autor:
Jetta Sandeep Kumar, B. Thirupataiah, Jayesh Mudgal, Gangireddy Sujeevan Reddy, Guntipally Mounika, Kazi Amirul Hossain, Marina Rajadurai, Jessy Elizabeth Mathew, Gautham G. Shenoy, Kishore V. L. Parsa, Manojit Pal
Publikováno v:
Chemical Communications. 57:10091-10094
A Pd-catalysed regioselective synthesis of 4,5-disubstituted 7-membered N/O-heterocycles was achieved via the 7-endo-dig cyclization followed by C–C bond formation of 2-(1-alkynyl)phenylacetamide. The ligand/additive free cascade reaction proceeded
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 2526-2536 (2021)
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal
Graphical abstract
Because of high stability and slow unfolding rates of G-quadruplexes (G4), cells have evolved specialized helicases that disrupt these non-canonical DNA and RNA structures in an ATP-dependent manner. One example is DHX36, a DE
Because of high stability and slow unfolding rates of G-quadruplexes (G4), cells have evolved specialized helicases that disrupt these non-canonical DNA and RNA structures in an ATP-dependent manner. One example is DHX36, a DE
Autor:
Jetta Sandeep, Kumar, Gangireddy Sujeevan, Reddy, Raghavender, Medishetti, Kazi, Amirul Hossain, B, Thirupataiah, Jhansi, Edelli, Shilpak, Dilip Bele, Rebecca, Kristina Edwin, Alex, Joseph, Gautham G, Shenoy, C, Mallikarjuna Rao, Manojit, Pal
Publikováno v:
Bioorganic Chemistry. 124:105857
Addressing the increasing incidences of cancer worldwide along with the multifaceted problem of drug resistance via development of new anticancer agents has become an essential goal. Due to the known cytotoxic effects and reported Akt inhibitory pote
Autor:
Gangireddy Sujeevan, Reddy, Rajamanikkam, Kamaraj, Kazi Amirul, Hossain, Jetta Sandeep, Kumar, B, Thirupataiah, Raghavender, Medishetti, N, Sushma Sri, Parimal, Misra, Manojit, Pal
Publikováno v:
Bioorganic chemistry. 116
A series of indole based novel Schiff bases was designed as potential agonists of 5-HT
Autor:
B, Thirupataiah, Guntipally, Mounika, Gangireddy Sujeevan, Reddy, Jetta Sandeep, Kumar, Kazi Amirul, Hossain, Raghavender, Medishetti, Snigdha, Samarpita, Mahaboobkhan, Rasool, Jayesh, Mudgal, Jessy E, Mathew, Gautham G, Shenoy, C Mallikarjuna, Rao, Kiranam, Chatti, Kishore V L, Parsa, Manojit, Pal
Publikováno v:
European journal of medicinal chemistry. 221
While anti-inflammatory properties of isocoumarins are known their PDE4 inhibitory potential was not explored previously. In our effort the non-PDE4 inhibitor isocoumarins were transformed into the promising inhibitors via introducing an aminosulfony
Autor:
B. Thirupataiah, Harshavardhan Bhuktar, Guntipally Mounika, Gangireddy Sujeevan Reddy, Jetta Sandeep Kumar, Sharda Shukla, Kazi Amirul Hossain, Raghavender Medishetti, Snigdha Samarpita, Mahaboobkhan Rasool, P.C. Jagadish, Gautham G. Shenoy, Kishore V.L. Parsa, Manojit Pal
Publikováno v:
Bioorganic Chemistry. 121:105667
In search of potent and new anti-inflammatory agents, we explored a new class of isocoumarin derivatives possessing the 3-oxoalkyl moiety at C-4 position. These compounds were synthesized via the FeCl