Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Kazane Nishioka"'
Autor:
Hirofumi Ohashi, Koichi Watashi, Wakana Saso, Kaho Shionoya, Shoya Iwanami, Takatsugu Hirokawa, Tsuyoshi Shirai, Shigehiko Kanaya, Yusuke Ito, Kwang Su Kim, Takao Nomura, Tateki Suzuki, Kazane Nishioka, Shuji Ando, Keisuke Ejima, Yoshiki Koizumi, Tomohiro Tanaka, Shin Aoki, Kouji Kuramochi, Tadaki Suzuki, Takao Hashiguchi, Katsumi Maenaka, Tetsuro Matano, Masamichi Muramatsu, Masayuki Saijo, Kazuyuki Aihara, Shingo Iwami, Makoto Takeda, Jane A. McKeating, Takaji Wakita
Publikováno v:
iScience, Vol 24, Iss 4, Pp 102367- (2021)
Summary: Antiviral treatments targeting the coronavirus disease 2019 are urgently required. We screened a panel of already approved drugs in a cell culture model of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and identified two new a
Externí odkaz:
https://doaj.org/article/1e4d3b5f958548beb979ab19912ad646
Autor:
Shoya Iwanami, Kosaku Kitagawa, Hirofumi Ohashi, Yusuke Asai, Kaho Shionoya, Wakana Saso, Kazane Nishioka, Hisashi Inaba, Shinji Nakaoka, Takaji Wakita, Odo Diekmann, Shingo Iwami, Koichi Watashi
Publikováno v:
PLoS Biology, Vol 18, Iss 7, p e3000562 (2020)
Virus proliferation involves gene replication inside infected cells and transmission to new target cells. Once positive-strand RNA virus has infected a cell, the viral genome serves as a template for copying ("stay-strategy") or is packaged into a pr
Externí odkaz:
https://doaj.org/article/e84df583669145e9b48342c195f70c91
Autor:
Shiki Saito, Hirofumi Ohashi, Kou Nakamura, Junichiro Otagaki, Kazane Nishioka, Kota Nishiuchi, Ayaka Nakamura, Yukine Tsurukawa, Hisanobu Shibasaki, Hironobu Murakami, Masaki Nagane, Maiko Okada, Kouji Kuramochi, Koichi Watashi, Shinji Kamisuki
Publikováno v:
Chemical and Pharmaceutical Bulletin. 70:679-683
The liver X receptor is a nuclear hormone receptor that regulates lipid metabolism. Previously, we had demonstrated the antiviral properties of a liver X receptor antagonist associated with the hepatitis C virus and severe acute respiratory syndrome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b8c2ba680092a99f1a4f146c5ffa2be
https://doi.org/10.1248/cpb.c22-00345
https://doi.org/10.1248/cpb.c22-00345
Autor:
Kou Nakamura, Masako Yamasaki, Hirofumi Ohashi, Shiki Saito, Koudai Ashikawa, Kanna Sato, Kazane Nishioka, Yuka Suzuki, Yukine Tsurukawa, Kazuki Kanno, Nozomi Mosu, Hironobu Murakami, Masaki Nagane, Maiko Okada, Koichi Watashi, Shinji Kamisuki
Publikováno v:
Chemical and Pharmaceutical Bulletin.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e6f8d7fc99eba35eacccfeebc3ebf6f
https://doi.org/10.1248/cpb.c23-00243
https://doi.org/10.1248/cpb.c23-00243
Autor:
Kota Nishiuchi, Hirofumi Ohashi, Kazane Nishioka, Masako Yamasaki, Masateru Furuta, Takumi Mashiko, Shusuke Tomoshige, Kenji Ohgane, Shinji Kamisuki, Koichi Watashi, Kouji Kuramochi
Publikováno v:
Journal of Natural Products
We have previously reported that neoechinulin B (1a), a prenylated indole diketopiperazine alkaloid, shows antiviral activities against hepatitis C virus (HCV) via the inactivation of the liver X receptors (LXRs) and the resultant disruption of doubl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5311b8d48190c93cbba90fba41ce48e
https://doi.org/10.1021/acs.jnatprod.1c01120
https://doi.org/10.1021/acs.jnatprod.1c01120
Autor:
Yusuke Ito, Tsuyoshi Shirai, Koichi Watashi, Jane A. McKeating, Shingo Iwami, Kazuyuki Aihara, Tetsuro Matano, Kaho Shionoya, Shoya Iwanami, Takaji Wakita, Wakana Saso, Kouji Kuramochi, Hirofumi Ohashi, Makoto Takeda, Katsumi Maenaka, Tadaki Suzuki, Shigehiko Kanaya, Kazane Nishioka, Kwang Su Kim, Tomohiro Tanaka, Yoshiki Koizumi, Masamichi Muramatsu, Shin Aoki, Masayuki Saijo, Shuji Ando, Takatsugu Hirokawa, Keisuke Ejima
SummaryAntiviral treatments targeting the emerging coronavirus disease 2019 (COVID-19) are urgently required. We screened a panel of already-approved drugs in a cell culture model of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and id
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4226e02dcb1f1ddaf94bf1a148c11b9
Autor:
Hirofumi Ohashi, Koichi Watashi, Wakana Saso, Kaho Shionoya, Shoya Iwanami, Takatsugu Hirokawa, Takehisa Matsumoto, Tsuyoshi Shirai, Shigehiko Kanaya, Yusuke Ito, Kwang Su Kim, Takao Nomura, Tateki Suzuki, Kazane Nishioka, Shuji Ando, Keisuke Ejima, Yoshiki Koizumi, Tomohiro Tanaka, Shin Aoki, Kouji Kuramochi, Tadaki Suzuki, Mikako Shirouzu, Takao Hashiguchi, Katsumi Maenaka, Tetsuro Matano, Masamichi Muramatsu, Masayuki Saijo, Kazuyuki Aihara, Shingo Iwami, Makoto Takeda, Jane A. Mckeating, Takaji Wakita
Publikováno v:
SSRN Electronic Journal.
Antiviral treatments targeting the coronavirus disease 2019 (COVID-19) are urgently required. We screened a panel of already-approved drugs in a cell culture model of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and identified two new
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47772bf3ef012fa74ddac9f0557dba5e
https://doi.org/10.2139/ssrn.3631397
https://doi.org/10.2139/ssrn.3631397
Autor:
Hisashi Inaba, Shinji Nakaoka, Kazane Nishioka, Hirofumi Ohashi, Takaji Wakita, Yusuke Asai, Kosaku Kitagawa, Shoya Iwanami, Koichi Watashi, Shingo Iwami, Odo Diekmann
Viruses proliferate through both genome replication inside infected cells and transmission to new target cells or to new hosts. Each viral genome molecule in infected cells is used either for amplifying the intracellular genome as a template (“stay
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1499642d5dd96d8ae590c6237838af2
https://doi.org/10.1101/821710
https://doi.org/10.1101/821710
Autor:
Mai Kamata, Toshifumi Takeuchi, Kazane Nishioka, Hiroshi Ohrui, Kouji Kuramochi, Shusuke Tomoshige, Kota Nishiuchi, Shinji Kamisuki, Shogo Kamo, Masashi Iwamoto, Fumio Sugawara, Mizuki Oshima, Koichi Watashi, Ei Hayashi
Publikováno v:
Bioscience, biotechnology, and biochemistry. 84(2)
4′-Ethynyl-2-fluoro-2′-deoxyadenosine (EFdA) and 4′-ethynyl-2′-deoxyadenosine (EdA) are nucleoside analogues which inhibit human immunodeficiency virus type 1 (HIV-1) reverse transcriptase. EdAP, a cyclosaligenyl (cycloSal) phosphate derivati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::104caaea9f01b1a263316f7652a143de
https://pubmed.ncbi.nlm.nih.gov/31589093
https://pubmed.ncbi.nlm.nih.gov/31589093
Autor:
Kamata, Mai, Takeuchi, Toshifumi, Hayashi, Ei, Kazane Nishioka, Oshima, Mizuki, Iwamoto, Masashi, Nishiuchi, Kota, Kamo, Shogo, Shusuke Tomoshige, Watashi, Koichi, Kamisuki, Shinji, Ohrui, Hiroshi, Sugawara, Fumio, Kuramochi, Kouji
4′-Ethynyl-2-fluoro-2′-deoxyadenosine (EFdA) and 4′-ethynyl-2′-deoxyadenosine (EdA) are nucleoside analogues which inhibit human immunodeficiency virus type 1 (HIV-1) reverse transcriptase. EdAP, a cyclosaligenyl (cycloSal) phosphate derivati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::446835243438ece273750d57d79a29bd