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Anti-hepatitis C Virus Activity of Juglorubin Derivatives.

Autor: Ohashi H; Department of Applied Biological Science, Tokyo University of Science.; Department of Virology II, National Institute of Infectious Diseases.; Research Center for Drug and Vaccine Development, National Institute of Infectious Diseases., Nishioka K; Department of Applied Biological Science, Tokyo University of Science.; Department of Virology II, National Institute of Infectious Diseases., Kurihara T; Department of Applied Biological Science, Tokyo University of Science.; Department of Virology II, National Institute of Infectious Diseases.; Research Center for Drug and Vaccine Development, National Institute of Infectious Diseases., Nakamura K; School of Veterinary Medicine, Azabu University., Yamasaki M; Department of Applied Biological Science, Tokyo University of Science.; Department of Virology II, National Institute of Infectious Diseases.; Research Center for Drug and Vaccine Development, National Institute of Infectious Diseases., Ibayashi Y; Department of Applied Biological Science, Tokyo University of Science., Fuchiyama K; Department of Applied Biological Science, Tokyo University of Science., Kamo S; Department of Applied Biological Science, Tokyo University of Science.; Department of Synthetic Medicinal Chemistry, Faculty of Pharmaceutical Sciences, Hoshi University., Furuyama Y; Department of Applied Biological Science, Tokyo University of Science., Ohgane K; Department of Applied Biological Science, Tokyo University of Science.; Department of Chemistry, Ochanomizu University., Okada M; School of Bioscience and Biotechnology, Tokyo University of Technology., Kamisuki S; School of Veterinary Medicine, Azabu University.; Center for Human and Animal Symbiosis Science, Azabu University., Watashi K; Department of Applied Biological Science, Tokyo University of Science.; Department of Virology II, National Institute of Infectious Diseases.; Research Center for Drug and Vaccine Development, National Institute of Infectious Diseases., Kuramochi K; Department of Applied Biological Science, Tokyo University of Science.

Publikováno v: Chemical & pharmaceutical bulletin [Chem Pharm Bull (Tokyo)] 2023; Vol. 71 (11), pp. 843-845.

Cyclic Phthalate Esters as Liver X Receptor Antagonists with Anti-hepatitis C Virus and Anti-severe Acute Respiratory Syndrome Coronavirus 2 Properties.

Autor: Saito S; School of Veterinary Medicine, Azabu University., Ohashi H; Department of Applied Biological Science, Tokyo University of Science.; Department of Virology II, National Institute of Infectious Diseases.; Research Center for Drug and Vaccine Development, National Institute of Infectious Diseases., Nakamura K; School of Veterinary Medicine, Azabu University., Otagaki J; School of Veterinary Medicine, Azabu University., Nishioka K; Department of Applied Biological Science, Tokyo University of Science.; Department of Virology II, National Institute of Infectious Diseases., Nishiuchi K; Department of Applied Biological Science, Tokyo University of Science., Nakamura A; School of Veterinary Medicine, Azabu University., Tsurukawa Y; School of Veterinary Medicine, Azabu University., Shibasaki H; School of Veterinary Medicine, Azabu University., Murakami H; School of Veterinary Medicine, Azabu University.; Center for Human and Animal Symbiosis Science, Azabu University., Nagane M; School of Veterinary Medicine, Azabu University.; Center for Human and Animal Symbiosis Science, Azabu University., Okada M; School of Bioscience and Biotechnology, Tokyo University of Technology., Kuramochi K; Department of Applied Biological Science, Tokyo University of Science., Watashi K; Department of Applied Biological Science, Tokyo University of Science.; Department of Virology II, National Institute of Infectious Diseases.; Research Center for Drug and Vaccine Development, National Institute of Infectious Diseases., Kamisuki S; School of Veterinary Medicine, Azabu University.; Center for Human and Animal Symbiosis Science, Azabu University.

Publikováno v: Chemical & pharmaceutical bulletin [Chem Pharm Bull (Tokyo)] 2022; Vol. 70 (10), pp. 679-683.

Potential anti-COVID-19 agents, cepharanthine and nelfinavir, and their usage for combination treatment.

Autor: Ohashi H; Department of Virology II, National Institute of Infectious Diseases, Tokyo 162-8640, Japan.; Department of Applied Biological Science, Tokyo University of Science, Noda 278-8510, Japan., Watashi K; Department of Virology II, National Institute of Infectious Diseases, Tokyo 162-8640, Japan.; Department of Applied Biological Science, Tokyo University of Science, Noda 278-8510, Japan.; Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto 606-8507, Japan.; MIRAI, JST, Saitama 332-0012, Japan.; Research Center for Drug and Vaccine Development, National Institute of Infectious Diseases, Tokyo 162-8640, Japan., Saso W; Department of Virology II, National Institute of Infectious Diseases, Tokyo 162-8640, Japan.; The Institute of Medical Science, The University of Tokyo, Tokyo 108-8639, Japan.; AIDS Research Center, National Institute of Infectious Diseases, Tokyo 162-8640, Japan., Shionoya K; Department of Virology II, National Institute of Infectious Diseases, Tokyo 162-8640, Japan.; Department of Applied Biological Science, Tokyo University of Science, Noda 278-8510, Japan., Iwanami S; Department of Biology, Faculty of Sciences, Kyushu University, Fukuoka 812-8581, Japan., Hirokawa T; Cellular and Molecular Biotechnology Research Institute, National Institute of Advanced Industrial Science and Technology, Tokyo 135-0064, Japan.; Division of Biomedical Science, Faculty of Medicine, University of Tsukuba, Tsukuba 305-8575, Japan.; Transborder Medical Research Center, University of Tsukuba, Tsukuba 305-8575, Japan., Shirai T; Faculty of Bioscience, Nagahama Institute of Bio-Science and Technology, Nagahama 526-0829, Japan., Kanaya S; Graduate School of Science and Technology, Nara Institute of Science and Technology, Ikoma 630-0192, Japan., Ito Y; Department of Biology, Faculty of Sciences, Kyushu University, Fukuoka 812-8581, Japan., Kim KS; Department of Biology, Faculty of Sciences, Kyushu University, Fukuoka 812-8581, Japan., Nomura T; Center for Research and Education on Drug Discovery, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan., Suzuki T; Department of Virology, Faculty of Medicine, Kyushu University, Fukuoka 812-8582, Japan., Nishioka K; Department of Virology II, National Institute of Infectious Diseases, Tokyo 162-8640, Japan.; Department of Applied Biological Science, Tokyo University of Science, Noda 278-8510, Japan., Ando S; Department of Virology I, National Institute of Infectious Diseases, Tokyo 162-8640, Japan., Ejima K; Department of Epidemiology and Biostatistics, Indiana University School of Public Health-Bloomington, Bloomington, IN 47405, USA., Koizumi Y; National Center for Global Health and Medicine, Tokyo 162-8655, Japan., Tanaka T; Faculty of Pharmaceutical Sciences, Tokyo University of Science, Noda 278-8510, Japan., Aoki S; Faculty of Pharmaceutical Sciences, Tokyo University of Science, Noda 278-8510, Japan.; Research Institute for Science and Technology, Tokyo University of Science, Noda 278-8510, Japan., Kuramochi K; Department of Applied Biological Science, Tokyo University of Science, Noda 278-8510, Japan., Suzuki T; Department of Pathology, National Institute of Infectious Diseases, Tokyo 162-8640, Japan., Hashiguchi T; Department of Virology, Faculty of Medicine, Kyushu University, Fukuoka 812-8582, Japan., Maenaka K; Center for Research and Education on Drug Discovery, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan.; Laboratory of Biomolecular Science, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan.; Global Station for Biosurfaces and Drug Discovery, Center for Life Innovation, Hokkaido University, Sapporo 060-0812, Japan., Matano T; The Institute of Medical Science, The University of Tokyo, Tokyo 108-8639, Japan.; AIDS Research Center, National Institute of Infectious Diseases, Tokyo 162-8640, Japan., Muramatsu M; Department of Virology II, National Institute of Infectious Diseases, Tokyo 162-8640, Japan., Saijo M; Department of Virology I, National Institute of Infectious Diseases, Tokyo 162-8640, Japan., Aihara K; International Research Center for Neurointelligence, The University of Tokyo Institutes for Advanced Study, The University of Tokyo, Tokyo 113-8654, Japan., Iwami S; MIRAI, JST, Saitama 332-0012, Japan.; Department of Biology, Faculty of Sciences, Kyushu University, Fukuoka 812-8581, Japan.; Institute for the Advanced Study of Human Biology (ASHBi), Kyoto University, Kyoto 606-8501, Japan.; NEXT-Ganken Program, Japanese Foundation for Cancer Research (JFCR), Tokyo 135-8550, Japan.; Science Groove Inc., Fukuoka 810-0041, Japan., Takeda M; Department of Virology III, National Institute of Infectious Diseases, Tokyo 208-0011, Japan., McKeating JA; Nuffield Department of Medicine, University of Oxford, Oxford OX3 7FZ, UK., Wakita T; Department of Virology II, National Institute of Infectious Diseases, Tokyo 162-8640, Japan.

Publikováno v: IScience [iScience] 2021 Apr 23; Vol. 24 (4), pp. 102367. Date of Electronic Publication: 2021 Mar 26.

Should a viral genome stay in the host cell or leave? A quantitative dynamics study of how hepatitis C virus deals with this dilemma.

Autor: Iwanami S; Graduate School of Systems Life Sciences, Kyushu University, Fukuoka, Japan., Kitagawa K; Graduate School of Systems Life Sciences, Kyushu University, Fukuoka, Japan., Ohashi H; Department of Virology II, National Institute of Infectious Diseases, Tokyo, Japan.; Department of Applied Biological Science, Tokyo University of Science, Noda, Japan., Asai Y; Disease Control and Prevention Center, National Center for Global Health and Medicine, Tokyo, Japan., Shionoya K; Department of Virology II, National Institute of Infectious Diseases, Tokyo, Japan.; Department of Applied Biological Science, Tokyo University of Science, Noda, Japan., Saso W; Department of Virology II, National Institute of Infectious Diseases, Tokyo, Japan.; The Institute of Medical Science, The University of Tokyo, Tokyo, Japan., Nishioka K; Department of Virology II, National Institute of Infectious Diseases, Tokyo, Japan.; Department of Applied Biological Science, Tokyo University of Science, Noda, Japan., Inaba H; Graduate School of Mathematical Sciences, The University of Tokyo, Tokyo, Japan., Nakaoka S; Faculty of Advanced Life Science, Hokkaido University, Sapporo, Japan.; PRESTO, Japan Science and Technology Agency, Saitama, Japan., Wakita T; Department of Virology II, National Institute of Infectious Diseases, Tokyo, Japan., Diekmann O; Mathematisch Institute, Universiteit Utrecht, Utrecht, the Netherlands., Iwami S; Department of Biology, Faculty of Sciences, Kyushu University, Fukuoka, Japan.; MIRAI, JST, Saitama, Japan.; Institute for the Advanced Study of Human Biology (ASHBi), Kyoto University, Kyoto, Japan.; NEXT-Ganken Program, Japanese Foundation for Cancer Research (JFCR), Tokyo, Japan.; Science Groove, Inc., Fukuoka, Japan., Watashi K; Department of Virology II, National Institute of Infectious Diseases, Tokyo, Japan.; Department of Applied Biological Science, Tokyo University of Science, Noda, Japan.; MIRAI, JST, Saitama, Japan.; Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto, Japan.

Publikováno v: PLoS biology [PLoS Biol] 2020 Jul 30; Vol. 18 (7), pp. e3000562. Date of Electronic Publication: 2020 Jul 30 (Print Publication: 2020).