Deficient autophagy in epithelial stem cells drives aging in the freshwater cnidarian Hydra

Autor: Steven N. Austad, Nenad Slavko Suknovic, Kazadi Ekundayo, Quentin Schenkelaars, Brigitte Galliot, Yvan Wenger, Christoph Ruediger Bauer, Wanda Christa Buzgariu, Szymon Tomczyk, Kathleen E. Fischer

Publikováno v: Development (Cambridge, England)
Development, Vol. 147, No dev177840 (2020) pp. 1-16

Hydra possesses three distinct stem cell populations that continuously self-renew and prevent aging in Hydra vulgaris. However, sexual animals from the H. oligactis cold-sensitive strain Ho_CS develop an aging phenotype upon gametogenesis induction,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::604c469d1167a688a643e8818ba77af8
http://europepmc.org/articles/PMC6983715

List of Contributors

Autor: Emaad M. Abdel-Rahman, Hayley D. Ackerman, Abimbola Akintola, Gro V. Amdam, Gil Atzmon, Steve Austad, Sanket Awate, Márta Balaskó, Taraswi Banerjee, Clea Bárcena, Andrzej Bartke, Ivan Bassi, Mette Berendt, Maarten F. Bijlsma, Alessandro Bitto, Jennifer L. Bizon, Ilse Bollaerts, Marco Bonomi, Consuelo Borras, Brendan T. Bowman, Thomas Brioche, Robert M. Brosh, Richard E. Brown, Kerstin Buck, Sara N. Burke, Wanda Buzgariu, Ramón Cacabelos, M.A. Camina Martín, Beth K. Chaffee, Anthony W.S. Chan, Haolin Chen, Zhiguo Chen, In K. Cho, Angèle Chopard, Victoria C. Cogger, Alan A. Cohen, Rafael Confino, Fabio Coppedè, Anthony J. Costa, Jack D. Crouch, Justin Darcy, Lies De Groef, B. de Mateo Silleras, Sathyaseelan S. Deepa, Gina Devau, Marc Dhenain, Chantelle Dills, Megan F. Duffy, Francesca E. Duncan, Gilles Dupuis, Benjamin A. Eaton, Josephine M. Egan, Kazadi Ekundayo, Marina E. Emborg, D. Luke Fischer, Pascaline Fontes, Maria Lourdes Alarcon Fortepiani, Carl Fortin, Bernhard Franzke, Tamas Fülöp, Camelia Gabriel, Brigitte Galliot, Juan Gambini, Hugo Garneau, Laura Gasparini, Glenn S. Gerhard, David C. Gibson, Lucia Gimeno-Mallench, Victor Girard, Kimberly A. Greer, Kristin E. Gribble, Melanie R. Gubbels Bupp, Adalsteinn Gudmundsson, Andrea Hamann, Michael R. Hamblin, James M. Harper, Ronald Hart, Elizabeth Head, Heather R. Herd, Guadalupe Herrera, Fuki M. Hisama, David B. Hogan, Donna J. Holmes, Peter J. Hornsby, Susan E. Howlett, Ka Yi Hui, Thomas R. Jahn, Beatriz Jávega, William R. Jeffery, Sarah A. Johnson, Audrey Jones, Corinne A. Jones, Pálmi V. Jónsson, Alice E. Kane, David Karasik, Samuel Kean, Evan T. Keller, Jill M. Keller, Christopher J. Kemp, Ken S.K. Wong, Jens Krøll, Sanjay Kumar Bharti, Markku Kurkinen, Anis Larbi, Christelle Lasbleiz, Corinne Lautier, David G. Le Couteur, Aurelie Le Page, Hang Lin, Carlos López-Otín, Line Lottonen-Raikaslehto, Elizabeth R. Magden, Evgenia Makrantonaki, Fredric P. Manfredsson, David B. Mark Welch, Jose Marques-Lopes, Alicia Martínez-Romero, Cristina Mas-Bargues, Pablo Mayoral, Mark Mc Auley, Joseph A. McQuail, Mari Merentie, Nadine Mestre-Frances, Jeanette M. Metzger, Keith C. Meyer, Teresa A. Milner, Claudia M. Mizutani, Raymond J. Monnat, Kathleen Mooney, Lieve Moons, Joscha Muck, Ranganath Muniyappa, Jan O. Nehlin, Oliver Neubauer, Georgios Nikolakis, Jeffry S. Nyman, José-Enrique O’Connor, Junko Oshima, Heinz D. Osiewacz, Vassilios Papadopoulos, Mary Ellen Pavone, Graham Pawelec, Jan T. Pedersen, Gonzalo Perez-Lopez, Luca Persani, Erika Pétervári, Azadeh Peyman, Johannes F. Plate, Nicole K. Polinski, Guillaume Py, Tyler P. Quigley, Eric A. Rae, Jeffrey L. Ram, David Raubenheimer, Jane F. Reckelhoff, M.P. Redondo del Río, Jovy Rex-Al Panem Orbon, Arlan Richardson, Jürgen A. Ripperger, Ildikó Rostás, Michael Rouse, Olav Rueppell, Kurt W. Runge, Maryam Safdar, Sumathi Sankaran-Walters, Anthony C. Santago, Anneli Sarvimäki, Katherine R. Saul, Quentin Schenkelaars, Brandt L. Schneider, Trine Schütt, He Shen, Sooyoun Shin, Stephen J. Simpson, Jessica Smith, Terry W. Snell, Jessica M. Snyder, Samantha M. Solon-Biet, Szilvia Soós, Caryl E. Sortwell, Rui Sousa-Neves, Kathy Steece-Collier, Anne Steins, Alyson Sujkowski, Susan E. Swanberg, Oscar Teijido, Sri Harsha Tella, Judit Tenk, Szymon Tomczyk, Piper M. Treuting, Stéphanie G. Trouche, Rocky S. Tuan, Archana Unnikrishnan, Dario Riccardo Valenzano, Diana van Heemst, Jessie Van houcke, Tracey A. Van Kempen, Hanneke W.M. van Laarhoven, Jean-Michel Verdier, Jose Viña, Karl-Heinz Wagner, Devin Wahl, Yvan Wenger, Robert J. Wessells, Donna M. Wilcock, Jacek M. Witkowski, Esther Wong, Nicole Woodland, Licy L. Yanes Cardozo, Seppo Ylä-Herttuala, Sameh A. Youssef, Rong Yuan, Haitao Zhang, Zhongjun Zhou, Barry R. Zirkin, Christos C. Zouboulis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ba7e888964939c8c6fbd5869ee76eda7
https://doi.org/10.1016/b978-0-12-811353-0.01002-2

Hydra, a model system for deciphering the mechanisms of aging and resistance to aging

Autor: Quentin Schenkelaars, Szymon Tomczyk, Yvan Wenger, Kazadi Ekundayo, Victor Girard, Wanda Buzgariu, Steve Austad, Brigitte Galliot

The freshwater cnidarian polyp namedHydra, which can be mass-cultured in the laboratory, is characterized by a highly dynamic homeostasis with a continuous self-renewal of its three adult stem cell populations, the epithelial stem cells from the epid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9785488565e1c567e0d007d17bb04c30
https://doi.org/10.1101/155804

Conn's Handbook of Models for Human Aging

Autor: Jeffrey L. Ram, P. Michael Conn

Conn's Handbook of Models for Human Aging, Second Edition, presents key aspects of biology, nutrition, factors affecting lifespan, methods of age determination, use in research and the disadvantages/advantages of use. Using a multidisciplinary approa