Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Kaz O Reynhardt"'
Autor:
Anthony M. Treacy, Virginia M Platt, Christine M. Evangelista, Dominic C. Borie, Lynn Smith, Mark Yen, Jane M. Andrews, Peter J. Prince, Kefei Zhou, Wei-Jian Pan, Christine D Krill, Graham L. Radford-Smith, Jason M. Gow, Kaz O Reynhardt, Jonathan Lee, Zhigang Yu, David R. Doherty, Kathleen Köck, William A. Rees, Barbara A. Sullivan, Sonal K. Patel, Jing Jing Shen
Publikováno v:
British Journal of Clinical Pharmacology. 78:1315-1333
AIMS AMG 181 pharmacokinetics/pharmacodynamics (PK/PD), safety, tolerability and effects after single subcutaneous (s.c.) or intravenous (i.v.) administration were evaluated in a randomized, double-blind, placebo-controlled study. METHODS Healthy mal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4affc6406b420c1a3ccb1e05e144e99
https://doi.org/10.1111/bcp.12418
https://doi.org/10.1111/bcp.12418
Autor:
Peter J. Prince, Wei-Jian Pan, Larry C. Wienkers, XZ Xia, CM Sheckler, Hailing Hsu, C D Krill, Dominique C. Borie, AA Anderson, Ian Foltz, Palaniswami Rathanaswami, SP Lear, William A. Rees, Sonal K. Patel, F Lee, Kathy Manchulenko, BJ Harder, Doherty, JL Brandvig, JL Lynch, Brian Mingtung Chan, M Zhang, John A. Wisler, Kaz O Reynhardt
Publikováno v:
British Journal of Pharmacology. 169:51-68
Background and Purpose AMG 181 is a human anti-α4β7 antibody currently in phase 1 and 2 trials in subjects with inflammatory bowel diseases. AMG 181 specifically targets the α4β7 integrin heterodimer, blocking its interaction with mucosal address
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c278748ec53018255ae698adfb9c3f0e
https://doi.org/10.1111/bph.12134
https://doi.org/10.1111/bph.12134