Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Kazım Yalçın ARĞA"'
Publikováno v:
Biomarker Insights, Vol 19 (2024)
Background: Clinical biomarkers, allow better classification of patients according to their disease risk, prognosis, and/or response to treatment. Although affordable omics-based approaches have paved the way for quicker identification of putative bi
Externí odkaz:
https://doaj.org/article/243bcd9b3785462795897023817af81f
Publikováno v:
Cancer Medicine, Vol 12, Iss 24, Pp 22420-22436 (2023)
Abstract Acute myeloid leukemia (AML) is a heterogeneous disease and the most common form of acute leukemia with a poor prognosis. Due to its complexity, the disease requires the identification of biomarkers for reliable prognosis. To identify potent
Externí odkaz:
https://doaj.org/article/b60eb5f52de543cc838a716485ef6795
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/3d94d29769a446d0ad69614ba9f2decf
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionIntegrating interaction data with biological knowledge can be a critical approach for drug development or drug repurposing. In this context, host-pathogen-protein-protein interaction (HP-PPI) networks are useful instrument to uncover the
Externí odkaz:
https://doaj.org/article/abe358bd43ba4c3aa3ffbfa063a62e77
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Cervical cancer is the fourth most commonly diagnosed cancer worldwide and, in almost all cases is caused by infection with highly oncogenic Human Papillomaviruses (HPVs). On the other hand, inflammation is one of the hallmarks of cancer research. He
Externí odkaz:
https://doaj.org/article/d6031e116f1b4cc091301f22b6c0378e
Autor:
Beste Turanli, Cheng Zhang, Woonghee Kim, Rui Benfeitas, Mathias Uhlen, Kazim Yalcin Arga, Adil Mardinoglu
Publikováno v:
EBioMedicine, Vol 42, Iss , Pp 386-396 (2019)
Background: Genome-scale metabolic models (GEMs) offer insights into cancer metabolism and have been used to identify potential biomarkers and drug targets. Drug repositioning is a time- and cost-effective method of drug discovery that can be applied
Externí odkaz:
https://doaj.org/article/9cf566f76b6448b196142f1d5b3f9f34
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Colorectal cancer (CRC) is one of the most fatal types of cancers that is seen in both men and women. CRC is the third most common type of cancer worldwide. Over the years, several drugs are developed for the treatment of CRC; however, patients with
Externí odkaz:
https://doaj.org/article/7fc054b5ff724f70ae33376c46be2be1
Autor:
Busra Aydin, Kazim Yalcin Arga
Publikováno v:
Frontiers in Endocrinology, Vol 10 (2019)
Non-functioning pituitary adenomas (NFPAs) are tumors with clinically challenging features since they have insidious progression. A complex network of gene interactions is thought to have roles in tumor formation and progression. Therefore, revealing
Externí odkaz:
https://doaj.org/article/3e71093c342c49f8928be4e1382b2374
Autor:
Beste Turanli, Kubra Karagoz, Gholamreza Bidkhori, Raghu Sinha, Michael L. Gatza, Mathias Uhlen, Adil Mardinoglu, Kazim Yalcin Arga
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
Triple-negative breast cancer (TNBC), which is largely synonymous with the basal-like molecular subtype, is the 5th leading cause of cancer deaths for women in the United States. The overall prognosis for TNBC patients remains poor given that few tre
Externí odkaz:
https://doaj.org/article/0f949e5bb75d42eebdd9afa7cdc0896a
Autor:
Md Rezanur Rahman, Maria Cristina Petralia, Rosella Ciurleo, Alessia Bramanti, Paolo Fagone, Md Shahjaman, Lang Wu, Yanfa Sun, Beste Turanli, Kazim Yalcin Arga, Md Rafiqul Islam, Tania Islam, Ferdinando Nicoletti
Publikováno v:
Brain Sciences, Vol 10, Iss 10, p 747 (2020)
Background: Autism spectrum disorder (ASD) is a neurodevelopmental disorder with deficits in social communication ability and repetitive behavior. The pathophysiological events involved in the brain of this complex disease are still unclear. Methods:
Externí odkaz:
https://doaj.org/article/9734451d5d664ce5b40b40495d7ff407