Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Kayo Yukawa"'
Autor:
Kayo Yukawa, Satomi Yamamoto-Mcguire, Louis Cafaro, Christine Hong, Fredrik Kamme, Tsuneya Ikezu, Seiko Ikezu
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-12 (2023)
Abstract Tau tubulin kinase-1 (TTBK1), a neuron-specific tau kinase, is highly expressed in the entorhinal cortex and hippocampal regions, where early tau pathology evolves in Alzheimer’s disease (AD). The protein expression level of TTBK1 is eleva
Externí odkaz:
https://doaj.org/article/211e531676fe4141a9564a629434326f
Autor:
Mitsuo Wada, Kayo Yukawa, Hiroyuki Ogasawara, Koichi Suzawa, Tatsuya Maekawa, Yoshihisa Yamamoto, Takeshi Ohta, Eunyoung Lee, Takashi Miki
Publikováno v:
iScience, Vol 24, Iss 4, Pp 102260- (2021)
Summary: Gpr52 is an orphan G-protein-coupled receptor of unknown physiological function. We found that Gpr52-deficient (Gpr52−/−) mice exhibit leanness associated with reduced liver weight, decreased hepatic de novo lipogenesis, and enhanced ins
Externí odkaz:
https://doaj.org/article/3b1c0f5f31334cc39db7149e6b8aed61
Autor:
Muraoka, Satoshi, M DeLeo, Annina, Yang, Zijian, Harutsugu, Tatebe, Kayo, Yukawa-Takamatsu, Ikezu, Seiko, Takahiko, Tokuda, Issadore, David, A Stern, Robert, Ikezu, Tsuneya
Publikováno v:
Aging and Disease. 12(6):1363-1375
Chronic Traumatic Encephalopathy (CTE) is a tauopathy that affects individuals with a history of exposure to repetitive head impacts, including National Football League (NFL) players. Extracellular vesicles (EVs) are known to carry tau in Alzheimer
Autor:
Harutsugu Tatebe, David Issadore, Tsuneya Ikezu, Takahiko Tokuda, Robert S. Stern, Seiko Ikezu, Kayo Yukawa-Takamatsu, Annina M. DeLeo, Zijian Yang, Satoshi Muraoka
Publikováno v:
Aging and Disease
Chronic Traumatic Encephalopathy (CTE) is a tauopathy that affects individuals with a history of exposure to repetitive head impacts, including National Football League (NFL) players. Extracellular vesicles (EVs) are known to carry tau in Alzheimer's
Autor:
Zhi Ruan, Satoshi Muraoka, Jina Ko, Yang You, David Issadore, Howard E. Gendelman, Yuzhi Wang, Joseph Zaia, Kayo Yukawa-Takamatsu, Annina M. DeLeo, John D. Hogan, Manveen K. Sethi, Tsuneya Ikezu, Mei Chen, Maria Medalla, Zijian Yang, Seiko Ikezu, Santhi Gorantla, Weiming Xia
Publikováno v:
Alzheimers Dement
IntroductionExtracellular vesicles (EVs) from human Alzheimer’s disease (AD) biospecimens contain amyloid-β peptide (Aβ) and tau. While AD EVs are known to affect brain disease pathobiology, their biochemical and molecular characterizations remai
Convenient Retinoid X Receptor Binding Assay Based on Fluorescence Change of the Antagonist NEt-C343
Autor:
Masaki Watanabe, Shoya Yamada, Kayo Yukawa-Takamatsu, Michiko Fujihara, Yuta Takamura, Hiroki Kakuta, Mayu Kawasaki, Sohei Ito, Shogo Nakano, Shota Kikuzawa, Mariko Nakamura-Nakayama, Yifei Wang, Makoto Makishima
Publikováno v:
Journal of medicinal chemistry. 64(1)
Retinoid X receptor (RXR) modulators (rexinoids) are considered to have therapeutic potential for multiple diseases, such as Alzheimer's disease and Parkinson's disease. To overcome various disadvantages of prior screening methods, we previously deve
Autor:
Harutsugu Tatebe, Takahiko Tokuda, David Issadore, Zijian Yang, Jina Ko, Katherine Wang, Steven P. Gygi, Satoshi Muraoka, Kayo Yukawa, Tsuneya Ikezu, Robert S. Stern, Seiko Ikezu, Mark P. Jedrychowski, Annina M. DeLeo
Publikováno v:
Alzheimer's & Dementia. 16
Autor:
Mitsuo Wada, Hiroyuki Ogasawara, Takashi Miki, Suzawa Koichi, Tatsuya Maekawa, Eun Young Lee, Takeshi Ohta, Kayo Yukawa, Yoshihisa Yamamoto
Publikováno v:
iScience
iScience, Vol 24, Iss 4, Pp 102260-(2021)
iScience, Vol 24, Iss 4, Pp 102260-(2021)
Summary Gpr52 is an orphan G-protein-coupled receptor of unknown physiological function. We found that Gpr52-deficient (Gpr52−/−) mice exhibit leanness associated with reduced liver weight, decreased hepatic de novo lipogenesis, and enhanced insu
Autor:
Zhi Ruan, Santhi Gorantla, David Issadore, Joseph Zaia, Srinidhi V. Kalava, Manveen K. Sethi, Tsuneya Ikezu, Kayo Yukawa, Howard E. Gendelman, Zijian Yang, Annina M. DeLeo, John D. Hogan, Satoshi Muraoka, Jina Ko, Yang You, Seiko Ikezu
Publikováno v:
Alzheimer's & Dementia. 15
Autor:
Satoshi Muraoka, DeLeo, Annina M., Zijian Yang, Harutsugu Tatebe, Kayo Yukawa-Takamatsu, Seiko Ikezu, Takahiko Tokuda, Issadore, David, Stern, Robert A., Tsuneya Ikezu
Publikováno v:
Aging & Disease; Sep2021, Vol. 12 Issue 6, p1363-1375, 13p