Výsledky vyhledávání - "Kayo TOMIYAMA"

Establishment of a human microbiome- and immune system-reconstituted dual-humanized mouse model

Autor: Yuyo KA, Ryoji ITO, Ryoko NOZU, Kayo TOMIYAMA, Masami UENO, Tomoyuki OGURA, Riichi TAKAHASHI

Publikováno v: Experimental Animals.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e75b265f2ec8f68bdb4a1d966dd6041e
https://doi.org/10.1538/expanim.23-0025

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Improved engraftment of human peripheral blood mononuclear cells in NOG MHC double knockout mice generated using CRISPR/Cas9

Autor: Riichi Takahashi, Jochen Welcker, Yuyo Ka, Kayo Tomiyama, Misa Mochizuki, Ryoji Ito, Taichi Yamamoto, Tomoyuki Ogura, Motohito Goto, Mamoru Ito, Kenji Kawai, Ikumi Katano, Eiko Nishinaka

Publikováno v: Immunology Letters. 229:55-61

Humanized mice are widely used to study the human immune system in vivo and develop therapies for various human diseases. Human peripheral blood mononuclear cells (PBMC)-engrafted NOD/Shi-scid IL2rγnull (NOG) mice are useful models for characterizat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49958c87cac112f390ed0e4a72627787
https://doi.org/10.1016/j.imlet.2020.11.011

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Creation of an experimental rearing environment for microbiome animal research using an individually ventilated cage system and bioBUBBLE enclosure

Autor: Masami Ueno, Kayo Tomiyama, Mariko Hamano, Yuyo Ka, Yuya Nozawa, Nobuyuki Tsuruzono, Tomoyuki Ogura, Ryoko Nozu, Akira Takakura, Riichi Takahashi

Publikováno v: Experimental Animals

To avoid microbial contamination risk, vinyl film isolators are generally used in animal microbiome experiments involving germ-free (GF) mice and/or gnotobiotic (GB) mice. However, it can take several months to gain expertise in operating the isolato

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3127ab4991e0552b85e63746df3811b
https://pubmed.ncbi.nlm.nih.gov/33239489

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Study on AAV-mediated gene therapy for diabetes in humanized liver mouse to predict efficacy in humans

Autor: Kenji Kawai, Tsuyoshi Chijiwa, Masato Nakamura, Mika Yagoto, Hiroshi Suemizu, Takahiro Kagawa, Tomoko Mizushima, Kayo Tomiyama, Tomoyuki Ogura, Riichi Takahashi, Haruo Hashimoto

Publikováno v: Biochemical and Biophysical Research Communications. 478:1254-1260

Most in vivo studies on the conversion to insulin-producing cells with AAV carrying PDX1 gene are performed in rodents. However, there is little information regarding Adeno-associated virus (AAV) carrying PDX1 gene transduced to human liver in vivo b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbfbf9a254fd868c7c53d19957178ec1
https://doi.org/10.1016/j.bbrc.2016.08.104

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