Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Kaylesh J. Dullabh"'
Autor:
Laurelle Jackson, Jessica Hunter, Sandile Cele, Isabella Markham Ferreira, Andrew C Young, Farina Karim, Rajhmun Madansein, Kaylesh J Dullabh, Chih-Yuan Chen, Noel J Buckels, Yashica Ganga, Khadija Khan, Mikael Boulle, Gila Lustig, Richard A Neher, Alex Sigal
Publikováno v:
eLife, Vol 7 (2018)
HIV has been reported to be cytotoxic in vitro and in lymph node infection models. Using a computational approach, we found that partial inhibition of transmissions of multiple virions per cell could lead to increased numbers of live infected cells.
Externí odkaz:
https://doaj.org/article/f962e22d605a430eaff5df1cc72a02f5
Autor:
Ann-Kathrin Reuschl, Dejan Mesner, Maitreyi Shivkumar, Matthew V.X. Whelan, Laura J. Pallett, José Afonso Guerra-Assunção, Rajhmun Madansein, Kaylesh J. Dullabh, Alex Sigal, John P. Thornhill, Carolina Herrera, Sarah Fidler, Mahdad Noursadeghi, Mala K. Maini, Clare Jolly
Publikováno v:
Cell Reports
open access article HIV-1 replicates in CD4+ T cells, leading to AIDS. Determining how HIV-1 shapes its niche to create a permissive environment is central to informing efforts to limit pathogenesis, disturb reservoirs, and achieve a cure. A key road
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77adfe2ac7f62c439980d800cda2f0e5
https://doi.org/10.1016/j.celrep.2022.110650
https://doi.org/10.1016/j.celrep.2022.110650
Autor:
Kaylesh J. Dullabh, Farina Karim, Rajhmun Madansein, Paul Ogongo, Samuel M. Behar, Alasdair Leslie, Adrie J. C. Steyn, Ismael Awala
Publikováno v:
The Journal of Clinical Investigation
Unconventional T cells that recognize mycobacterial antigens are of great interest as potential vaccine targets against tuberculosis (TB). This includes donor-unrestricted T cells (DURTs), such as mucosa-associated invariant T cells (MAITs), CD1-rest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a86fed05e7214cf026ee0acd1d63ee6
https://doi.org/10.1172/jci130711
https://doi.org/10.1172/jci130711
Autor:
Alessandra Nardin, Rajhmun Madansein, Amanda Ardain, Khadija Khan, Kaylesh J. Dullabh, Alveera Singh, Taryn Naidoo, Alessandro Sette, Farina Karim, Samuel M. Behar, Alasdair Leslie, Paul T. Elkington, Liku B. Tezera, Duran Ramsuran, Michael G. Fehlings, Abigail Ngoepe, Paul Ogongo, Cecilia S. Lindestam Arlehamn, Henrik N. Kløverpris, Shepherd Nhamoyebonde, Adrie J. C. Steyn, Boon Heng Lee
Publikováno v:
The Journal of Clinical Investigation
Ogongo, P, Tezera, L B, Ardain, A, Nhamoyebonde, S, Ramsuran, D, Singh, A, Ng’oepe, A, Karim, F, Naidoo, T, Khan, K, Dullabh, K J, Fehlings, M, Lee, B H, Nardin, A, Lindestam Arlehamn, C S, Sette, A, Behar, S M, Steyn, A J C, Madansein, R, Kløverpris, H N, Elkington, P T & Leslie, A 2021, ' Tissue-resident-like CD4 + T cells secreting IL-17 control Mycobacterium tuberculosis in the human lung ', Journal of Clinical Investigation, vol. 131, no. 10, e142014 . https://doi.org/10.1172/JCI142014
Ogongo, P, Tezera, L B, Ardain, A, Nhamoyebonde, S, Ramsuran, D, Singh, A, Ng’oepe, A, Karim, F, Naidoo, T, Khan, K, Dullabh, K J, Fehlings, M, Lee, B H, Nardin, A, Lindestam Arlehamn, C S, Sette, A, Behar, S M, Steyn, A J C, Madansein, R, Kløverpris, H N, Elkington, P T & Leslie, A 2021, ' Tissue-resident-like CD4 + T cells secreting IL-17 control Mycobacterium tuberculosis in the human lung ', Journal of Clinical Investigation, vol. 131, no. 10, e142014 . https://doi.org/10.1172/JCI142014
T cell immunity is essential for the control of tuberculosis (TB), an important disease of the lung, and is generally studied in humans using peripheral blood cells. Mounting evidence, however, indicates that tissue-resident memory T cells (Trms) are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c54f1e337bceef35ac1e1654d343094
http://europepmc.org/articles/PMC8121523
http://europepmc.org/articles/PMC8121523
Autor:
Mala K. Maini, Rajhmun Madansein, Ann-Kathrin Reuschl, Clemency Jolly, Dejan Mesner, John Thornhill, Alex Sigal, Kaylesh J. Dullabh, Laura J. Pallett, Shivkumar M, Sarah Fidler, Carolina Herrera, José Afonso Guerra-Assunção, Mahdad Noursadeghi
Human immunodeficiency virus type 1 (HIV-1) replicates in CD4+ T cells leading to profound T cell loss, immunological dysfunction and AIDS. Determining how HIV-1 shapes the immunological niche in which it resides to create a permissive environment is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c4d65d83c6fb11ebe8e9a28582a1bd2
https://doi.org/10.1101/2021.01.25.428084
https://doi.org/10.1101/2021.01.25.428084
Autor:
Kaylesh J. Dullabh, Kameel Maharaj
Publikováno v:
African Journal of Thoracic and Critical Care Medicine
A solitary pulmonary nodule is a single, well-circumscribed radiographic opacity that will be encountered by every thoracic surgeon, and management is dependent on the malignant potential of the nodule. The nodules are usually first encountered on a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07d169d89bf12ea36dada47e397ce45b
https://doi.org/10.7196/ajtccm.2020.v26i1.053
https://doi.org/10.7196/ajtccm.2020.v26i1.053
Autor:
Khadija Khan, Kaylesh J. Dullabh, Isabella Markham Ferreira, N J Buckels, Chih-Yuan Chen, Gila Lustig, Mikael Boulle, Jessica Hunter, Sandile Cele, Alex Sigal, Yashica Ganga, Andrew C. Young, Laurelle Jackson, Farina Karim, Richard A. Neher, Rajhmun Madansein
Publikováno v:
eLife
eLife, Vol 7 (2018)
eLife, Vol 7 (2018)
HIV has been reported to be cytotoxic in vitro and in lymph node infection models. Using a computational approach, we found that partial inhibition of transmissions of multiple virions per cell could lead to increased numbers of live infected cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cd82731578c00cd7abde67aea952393
https://hdl.handle.net/21.11116/0000-0001-3AB3-421.11116/0000-0001-3AB5-2
https://hdl.handle.net/21.11116/0000-0001-3AB3-421.11116/0000-0001-3AB5-2
Autor:
Jessica Hunter, Richard A. Neher, N J Buckels, Isabella Markham Ferreira, Chih-Yuan Chen, Khadija Khan, Kaylesh J. Dullabh, Rajhmun Madansein, Alex Sigal, Yashica Ganga, Sandile Cele, Farina Karim, Gila Lustig, Andrew C. Young, Laurelle Jackson, Mikael Boulle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::681649ab9631b1ec25615f602ee1e4a9
https://doi.org/10.7554/elife.30134.040
https://doi.org/10.7554/elife.30134.040
Autor:
Nicole C Howard, William G. C. Horsnell, Amanda Ardain, Shabaana A. Khader, Javier Rangel-Moreno, Alveera Singh, Shibali Das, Tyler K. Ulland, Alex K. Shalek, Takashi Ebihara, Jay K. Kolls, Wayne M. Yokoyama, Mushtaq Ahmed, Rajhmun Madansein, Samuel W. Kazer, Nancy Marin-Agudelo, Maria de la Luz Garcia-Hernandez, Kaylesh J. Dullabh, Thumbi Ndung'u, Lan Lu, Micah D. Dunlap, Matthew Darby, Paul Ogongo, Duran Ramsuran, Alexander Pym, Joaquín Zúñiga, Deepak Kaushal, Marco Colonna, Alasdair Leslie, Racquel Domingo-Gonzalez, Eugene Park, Farina Karim, Henrik N. Kløverpris, Shepherd Nhamoyebonde, Adrie J. C. Steyn, Laura Melocchi
Publikováno v:
Nature. 572:E10-E10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c847d4df5305e935d0dbdfeeb5cccce3
https://doi.org/10.1038/s41586-019-1458-y
https://doi.org/10.1038/s41586-019-1458-y
Autor:
William G. C. Horsnell, Amanda Ardain, Alveera Singh, Mushtaq Ahmed, Laura Melocchi, Javier Rangel-Moreno, Nicole C Howard, Duran Ramsuran, Wayne M. Yokoyama, Deepak Kaushal, Samuel W. Kazer, Maria de la Luz Garcia-Hernandez, Nancy Marin-Agudelo, Matthew Darby, Tyler K. Ulland, Henrik N. Kløverpris, Thumbi Ndung'u, Shepherd Nhamoyebonde, Adrie J. C. Steyn, Lan Lu, Shabaana A. Khader, Micah D. Dunlap, Alexander Pym, Joaquín Zúñiga, Jay K. Kolls, Takashi Ebihara, Marco Colonna, Alasdair Leslie, Shibali Das, Alex K. Shalek, Racquel Domingo-Gonzalez, Eugene Park, Rajhmun Madansein, Farina Karim, Kaylesh J. Dullabh, Paul Ogongo
Publikováno v:
Nature
Nature, Nature Publishing Group, 2019, 570 (7762), pp.528-532. ⟨10.1038/s41586-019-1276-2⟩
Frontiers in Immunology
Nature, Nature Publishing Group, 2019, 570 (7762), pp.528-532. ⟨10.1038/s41586-019-1276-2⟩
Frontiers in Immunology
Tuberculosis is the leading cause of death by an infectious disease worldwide1. However, the involvement of innate lymphoid cells (ILCs) in immune responses to infection with Mycobacterium tuberculosis (Mtb) is unknown. Here we show that circulating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d2922633fddebe3d38b9ab31ba54d3d