Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Kayleigh A. Swaggart"'
Autor:
Caitlin E Dunn-Fletcher, Lisa M Muglia, Mihaela Pavlicev, Gernot Wolf, Ming-An Sun, Yueh-Chiang Hu, Elizabeth Huffman, Shivani Tumukuntala, Katri Thiele, Amrita Mukherjee, Sandra Zoubovsky, Xuzhe Zhang, Kayleigh A Swaggart, Katherine Y Bezold Lamm, Helen Jones, Todd S Macfarlan, Louis J Muglia
Publikováno v:
PLoS Biology, Vol 16, Iss 9, p e2006337 (2018)
Pregnancy and parturition are intricately regulated to ensure successful reproductive outcomes. However, the factors that control gestational length in humans and other anthropoid primates remain poorly defined. Here, we show the endogenous retrovira
Externí odkaz:
https://doaj.org/article/5187b61a9cc04b9bb9eb293210d8a053
Autor:
Leandra K. Tolusso, Daniel T. Swarr, Kristen Suhrie, Hua He, Kayleigh A. Swaggart, D. Brian Dawson
Publikováno v:
The Journal of pediatrics. 213
To investigate the prevalence of genetic disease and its economic impact in a level IV neonatal intensive care unit (NICU) by identifying and describing diseases diagnosed, genetic testing methodologies used, timing of diagnosis, length of NICU stay,
Autor:
Anna Woo, Michele Hadhazy, Patrick Page, Alexis R. Demonbreun, Katherine S. Fallon, Stanley F. Nelson, Ascia Eskin, Kevin Squire, Kayleigh A. Swaggart, Andy H. Vo, Zugen Chen, Quan Q. Gao, Mattia Quattrocelli, Elizabeth M. McNally
Publikováno v:
Human Molecular Genetics.
Like other single-gene disorders, muscular dystrophy displays a range of phenotypic heterogeneity even with the same primary mutation. Identifying genetic modifiers capable of altering the course of muscular dystrophy is one approach to deciphering g
Publikováno v:
Genome Biology and Evolution
Transposable elements (TEs) comprise approximately half of the human genome, and several independent lines of investigation have demonstrated their role in rewiring gene expression during development, evolution, and oncogenesis. The identification of
Publikováno v:
Journal of Neuromuscular Diseases. 2:39-49
Background: The muscular dystrophies target muscle groups differentially. In mouse models of muscular dystrophy, notably the mdx model of Duchenne Muscular Dystrophy, the diaphragm muscle shows marked fibrosis and at an earlier age than other muscle
Publikováno v:
Experimental Physiology. 99:621-626
New Findings What is the topic of this review? Genetic modifiers act on many different physiological aspects of muscle disease. Understanding and identifying such modifiers is important because their discovery may help to predict the course of muscle
Publikováno v:
Physiological Genomics. 43:24-31
Phenotypic expression in the muscular dystrophies is variable, even with the identical mutation, providing strong evidence that genetic modifiers influence outcome. To identify genetic modifier loci, we used quantitative trait locus mapping in two di
Autor:
Lisa M. Muglia, Kayleigh A. Swaggart, Mihaela Pavlicev, Katherine Young Bezold Lamm, Elizabeth Huffman, Gernot Wolf, Shivani Tumukuntala, Yueh-Chiang Hu, Todd S. Macfarlan, Sandra P. Zoubovsky, Helen Jones, Louis J. Muglia, Ming-an Sun, Amrita Mukherjee, Caitlin E. Dunn-Fletcher, Xuzhe Zhang, Katri Thiele
Publikováno v:
PLoS Biology
PLoS Biology, Vol 16, Iss 9, p e2006337 (2018)
PLoS Biology, Vol 16, Iss 9, p e2006337 (2018)
Pregnancy and parturition are intricately regulated to ensure successful reproductive outcomes. However, the factors that control gestational length in humans and other anthropoid primates remain poorly defined. Here, we show the endogenous retrovira
Autor:
Michael J. Scanlon, Brent Buckner, Diane Janick-Buckner, Cheryl C. Wong, Kelsey M. Aurand, Patrick S. Schnable, Heath A. Smith, Kayleigh A. Swaggart
Publikováno v:
Journal of Heredity. 99:407-416
The K homology (KH) domain is a conserved sequence present in a wide variety of RNA-binding proteins. The rough sheath2-interacting KH domain (RIK) protein of maize has been implicated in the maintenance of the repressed chromatin state of knox genes
Autor:
Peter Pytel, Se-Jin Lee, Elizabeth M. McNally, Elisabeth R. Barton, Min Liu, Adam Lehar, C. Conover Talbot, Yun-Sil Lee, Kayleigh A. Swaggart, Suzanne Sebald
Publikováno v:
Human Molecular Genetics
Myostatin is a secreted signaling molecule that normally acts to limit muscle growth. As a result, there is extensive effort directed at developing drugs capable of targeting myostatin to treat patients with muscle loss. One potential concern with th