Vortioxetine Reduces Marble Burying but Only Transiently Enhances Social Interaction Preference in Adult Male BTBR T+Itpr3tf/J Mice

Autor: Georgianna G. Gould, Benita Lee, Connie Sanchez, Alan L. Pehrson, Wynne Q. Zhang, Kaylee Ghent, Nasriya A. Witt

Publikováno v: Witt, N A, Lee, B, Ghent, K, Zhang, W Q, Pehrson, A L, Sánchez, C & Gould, G G 2019, ' Vortioxetine Reduces Marble Burying but Only Transiently Enhances Social Interaction Preference in Adult Male BTBR T + Itpr3 tf /J Mice ', ACS Chemical Neuroscience, vol. 10, no. 10, pp. 4319-4327 . https://doi.org/10.1021/acschemneuro.9b00386

Vortioxetine is a multimodal antidepressant with agonist activity at serotonin (5-HT) 1A and 5-HT 1B receptors that blocks the 5-HT transporter (SERT). Previously in male BTBR T +Itpr3 tf/J (BTBR) mice, the 5-HT 1A partial agonist buspirone and SERT

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