Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Kayla M. Quinnies"'
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0171977 (2017)
Di-(2-ethylhexyl) phthalate (DEHP) is an endocrine disrupting chemical commonly used as a plasticizer in medical equipment, food packaging, flooring, and children's toys. DEHP exposure during early development has been associated with adverse neurobe
Externí odkaz:
https://doaj.org/article/ba90c0aa3cb34ee78707d461a8d294d8
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology
CPT: Pharmacometrics & Systems Pharmacology, Vol 7, Iss 7, Pp 453-463 (2018)
CPT: Pharmacometrics & Systems Pharmacology, Vol 7, Iss 7, Pp 453-463 (2018)
Understanding the downstream consequences of pharmacologically targeted proteins is essential to drug design. Current approaches investigate molecular effects under tissue‐naïve assumptions. Many target proteins, however, have tissue‐specific ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ece90e831f7a4044c00b53e4f43d490f
https://doi.org/10.1002/psp4.12305
https://doi.org/10.1002/psp4.12305
Autor:
Nicholas P. Tatonetti, Tal Lorberbaum, Kayla M. Quinnies, Vijendra Ramlall, David Goldstein, Rami Vanguri
Ancestry is an essential covariate in clinical genomics research. When genetic data are available, dimensionality reduction techniques, such as principal components analysis, are used to determine ancestry in complex populations. Unfortunately, these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b1539b1137accba893fa955fd142ed6
https://doi.org/10.1101/768440
https://doi.org/10.1101/768440
Autor:
Laura Geraldino-Pardilla, Kayla M. Quinnies, Anca D. Askanase, Yevgeniya Gartshteyn, Pooja Mahadeshwar, Nicholas P. Tatonetti, Teja Kapoor, Cathy Guo, Joyce Hui-Yuen
Publikováno v:
Lupus Science & Medicine
ObjectiveTo define the risk of progressive multifocal leukoencephalopathy (PML) in SLE.MethodsThis is a retrospective observational study to evaluate PML cases in patients with SLE admitted to two large academic hospitals. Using electronic medical re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abd48606999282c74806767f7f7806bf
https://doi.org/10.1136/lupus-2020-000388
https://doi.org/10.1136/lupus-2020-000388
Publikováno v:
Endocrinology. 156:3077-3083
Exposure to di-(2-ethylhexyl) phthalate (DEHP) has been linked to male reproductive abnormalities. Here, we assessed transgenerational actions of DEHP on several behaviors and stress responses. We used 2 doses of DEHP (150- and 200-mg/kg body weight)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::815caa2eedcc5914540e521b52abde8e
https://doi.org/10.1210/en.2015-1326
https://doi.org/10.1210/en.2015-1326
Publikováno v:
Behavioral Neuroscience. 129:331-338
Mice with severe combined immunodeficiency (SCID) lack functional T and B lymphocytes, and have impaired cognitive abilities. We assessed social behaviors in male SCID and C57BL/6 (B6) juvenile mice. In a social preference task, SCID mice spent more
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52d1868acd1fe8e13246f287be83d173
https://doi.org/10.1037/bne0000053
https://doi.org/10.1037/bne0000053
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 2, p e0171977 (2017)
PLoS ONE, Vol 12, Iss 2, p e0171977 (2017)
Di-(2-ethylhexyl) phthalate (DEHP) is an endocrine disrupting chemical commonly used as a plasticizer in medical equipment, food packaging, flooring, and children's toys. DEHP exposure during early development has been associated with adverse neurobe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64d40662eb7b6cdb22e6177990793319
https://pubmed.ncbi.nlm.nih.gov/28199414
https://pubmed.ncbi.nlm.nih.gov/28199414
Autor:
Krzysztof Kiryluk, Gillian M. Belbin, Patricia Glowe, Hojjat Salmasian, Joel T. Dudley, Li Li, Rami Vanguri, Fernanda Polubriaginof, George Hripcsak, Kayla M. Quinnies, Suzanne Bakken, David K. Vawdrey, Iuliana Ionita-Laza, Eimear E. Kenny, Victor Nwankwo, Mark M. Shervey, Alexandre Yahi, Tal Lorberbaum, Nicholas P. Tatonetti, Daniel G. Goldstein, Mary Simmerling
Heritability is essential for understanding the biological causes of disease, but requires laborious patient recruitment and phenotype ascertainment. Electronic health records (EHR) passively capture a wide range of clinically relevant data and provi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::693b66046c628a83b6526103fd20aa4a
https://doi.org/10.1101/066068
https://doi.org/10.1101/066068
Autor:
Nicholas P. Tatonetti, Jacob H. Rand, Ronald Realubit, Charles Karan, Jeremy B. Chang, Kayla M. Quinnies
Publikováno v:
Scientific Reports
A central challenge in designing and administering effective anticoagulants is achieving the proper therapeutic window and dosage for each patient. The Hill coefficient, nH, which measures the steepness of a dose-response relationship, may be a usefu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03e066f554b5256bcec5cc7ae6aee30a
Publikováno v:
Brain, Behavior, and Immunity. 25:379-385
It was recently shown that adaptive immunity plays a key role in cognitive function. T cells appear to be major players in learning and memory; thus, mice devoid of functional T cells are impaired in performance of cognitive tasks such as Morris Wate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2551e4cc813ebf4f16921a375d4e9bed
https://doi.org/10.1016/j.bbi.2010.11.009
https://doi.org/10.1016/j.bbi.2010.11.009