Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Kayla M, Nist"'
Publikováno v:
Frontiers in Physiology, Vol 12 (2022)
The mechanisms that sense alterations in total body sodium content to facilitate sodium homeostasis in response to an acute sodium challenge that does not increase blood pressure have not been fully elucidated. We hypothesized that the renal sympathe
Externí odkaz:
https://doaj.org/article/5523167cd6444161bb615634cee3e566
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
We have previously reported that brain Gαi2 subunit proteins are required to maintain sodium homeostasis and are endogenously upregulated in the hypothalamic paraventricular nucleus (PVN) in response to increased dietary salt intake to maintain a sa
Externí odkaz:
https://doaj.org/article/4c02f0509f544d89a07ab29ca54daea1
Autor:
Kayla M Nist, Richard D Wainford
Publikováno v:
Hypertension. 79
Aim: We hypothesize paraventricular nucleus (PVN)-specific blood brain barrier (BBB) disruption and neuroinflammation increase hypertension and sympathoexcitation with age, promoting cognitive impairment, that can be attenuated by an Angiotensin II T
Autor:
Kayla M. Nist, Richard D. Wainford
Publikováno v:
The FASEB Journal. 36
Publikováno v:
Frontiers in Physiology
Frontiers in Physiology, Vol 12 (2021)
Frontiers in Physiology, Vol 12 (2021)
We have previously reported that brain Gαi2 subunit proteins are required to maintain sodium homeostasis and are endogenously upregulated in the hypothalamic paraventricular nucleus (PVN) in response to increased dietary salt intake to maintain a sa
Publikováno v:
Frontiers in Physiology
The mechanisms that sense alterations in total body sodium content to facilitate sodium homeostasis in response to an acute sodium challenge that does not increase blood pressure have not been fully elucidated. We hypothesized that the renal sympathe
Publikováno v:
Hypertension. 78
Aim: Hypertension (HTN) and aging are associated with the development of vascular dysfunction. We speculated that vascular smooth muscle cell plasticity and vascular remodeling play major roles in age and sex-dependent HTN. Methods: Male and female S
Publikováno v:
Hypertension. 78
AIM: We hypothesized paraventricular nucleus (PVN)-specific blood-brain barrier (BBB) dysfunction and neuroinflammation contribute to hypertension and sympathoexcitation that can be attenuated by an Angiotensin II Type 1 Receptor (AT 1 R)-dependent m
Autor:
Tara L. Moore, Alissa A. Frame, Kayla M. Nist, Parul Chaudhary, Franco Puleo, Richard D Wainford, Jesse D. Moreira, Eric Abkin, Jonique C. George
Publikováno v:
Experimental Physiology
New findings • What is the central question of this study? We hypothesized that central inflammatory processes that involve activation of microglia and astrocytes contribute to the development of Gαi2 protein-dependent, salt-sensitive hypertension
Autor:
Eric Abkin, Franco Puleo, Erica Comsti, Jesse D. Moreira, Alissa A. Frame, Kiyoung Kim, Mohammed Z. Ferdaus, Richard D Wainford, Kayla M. Nist, Kathryn R Walsh, Elizabeth Faudoa
Publikováno v:
Physiol Res
Increased sympathoexcitation and renal sodium retention during high salt intake are hallmarks of the salt sensitivity of blood pressure. The mechanism(s) by which excessive sympathetic nervous system release of norepinephrine influences renal sodium