Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Kayla Kulhanek"'
Autor:
Lisiena Hysenaj, Samantha Little, Kayla Kulhanek, Melia Magnen, Kriti Bahl, Oghenekevwe M. Gbenedio, Morgan Prinz, Lauren Rodriguez, Christopher Andersen, Arjun Arkal Rao, Alan Shen, Jean-Christophe Lone, Leonard C. Lupin-Jimenez, Luke R. Bonser, Nina K. Serwas, Eran Mick, Mir M. Khalid, Taha Y. Taha, Renuka Kumar, Jack Z. Li, Vivianne W. Ding, Shotaro Matsumoto, Mazharul Maishan, Bharath Sreekumar, Camille Simoneau, Irina Nazarenko, Michael G. Tomlinson, Khajida Khan, Anne von Gottberg, Alex Sigal, Mark R. Looney, Gabriela K. Fragiadakis, David M. Jablons, Charles R. Langelier, Michael Matthay, Matthew Krummel, David J. Erle, Alexis J. Combes, Anita Sil, Melanie Ott, Johannes R. Kratz, Jeroen P. Roose
Publikováno v:
Stem Cell Reports
Stem cell reports, vol 18, iss 3
Stem cell reports, vol 18, iss 3
Ancestral SARS coronavirus-2 (SARS-CoV-2) and variants of concern (VOC) caused a global pandemic with a spectrum of disease severity. The mechanistic explaining variations related to airway epithelium are relatively understudied. Here, we biobanked a
Autor:
May Yee Szeto, Anjeli Mase, Kayla Kulhanek, Saikat Banerjee, Ignacio Rubio, Jeroen Roose, Neil Shah
Myeloid leukemias are frequently associated with pathologically activating mutations in tyrosine kinases [BCR-ABL1 in chronic myeloid leukemia (CML); FLT3 juxtamembrane internal tandem duplication (ITD) mutations, FLT3 and KIT activation loop mutatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb298e0f9045370f4d3614e8537f645f
https://doi.org/10.1101/2023.04.07.536070
https://doi.org/10.1101/2023.04.07.536070
Publikováno v:
Methods in Molecular Biology ISBN: 9781071611890
Ras research has experienced a considerable boost in recent years, not least prompted by the Ras initiative launched by the NCI in 2013 ( https://www.cancer.gov/research/key-initiatives/ras ), accompanied and conditioned by a strongly reinvigorated d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca62d7ccfd5f157775498af6c34207eb
https://doi.org/10.1007/978-1-0716-1190-6_2
https://doi.org/10.1007/978-1-0716-1190-6_2
Autor:
Matthijs J. D. Baars, Thera Douma, Yvonne Vercoulen, Michiel Vermeulen, Marijke P. Baltissen, Alexander Marson, Femke van Wijk, Darienne R. Myers, Mojtaba Amini, Sytze de Roock, Saikat Banerjee, Dimitre R. Simeonov, Susan Zwakenberg, Jeroen P. Roose, Kayla Kulhanek
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::765d483a19baab6370719d7069a9bea6
https://doi.org/10.1002/eji.201948451/v2/response1
https://doi.org/10.1002/eji.201948451/v2/response1
Autor:
Darienne R. Myers, Jeroen P. Roose, Yvonne Vercoulen, Olga Ksionda, Damia Romero-Moya, Kayla Kulhanek
Publikováno v:
STAR Protocols
STAR Protocols, Vol 1, Iss 2, Pp 100067-(2020)
STAR protocols, vol 1, iss 2
STAR Protocols, Vol 1, Iss 2, Pp 100067-(2020)
STAR protocols, vol 1, iss 2
Summary Stimulation of naive T lymphocytes via the T cell receptor (TCR) induces distinct phosphorylation patterns that can be used to explore various signaling pathways within the cell. This protocol can be used to characterize different perturbatio
Autor:
Alan Merk, Jana Ognjenovic, Kathryn Wong, Jeroen P. Roose, Yasushi Kondo, Sriram Subramaniam, Kayla Kulhanek, Deepti Karandur, Saikat Banerjee, John Kuriyan
Publikováno v:
Science (New York, N.Y.), vol 366, iss 6461
The yin and yang of Raf inhibition Many human melanomas contain an overactive form of Raf kinase (B-Raf). Inhibitors are effective against the mutant B-Raf, but, paradoxically, they activate wild-type B-Raf, limiting their therapeutic potential. Kond
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac15c249ae38ae5fd39dccea772b14df
https://europepmc.org/articles/PMC7007921/
https://europepmc.org/articles/PMC7007921/
Autor:
Marijke P. Baltissen, Susan Zwakenberg, Alexander Marson, Michiel Vermeulen, Suchandrima Banerjee, Dimitre R. Simeonov, Matthijs J. D. Baars, Thera Douma, S. de Roock, Darienne R. Myers, Yvonne Vercoulen, Jeroen P. Roose, F van Wijk, Kayla Kulhanek
RasGRP1 is a Ras guanine nucleotide exchange factor, and an essential regulator of lymphocyte receptor signaling. In mice, Rasgrp1 deletion results in defective T lymphocyte development. RASGRP1-deficient patients suffer from immune deficiency, and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37eba3e5d5843e829aee5ebb8d3a088e
Publikováno v:
Prof. Chakraborty via Ye Li
Science signaling, vol 12, iss 591
Sci Signal
Science signaling, vol 12, iss 591
Sci Signal
T cell receptor (TCR) stimulation activates diverse kinase pathways, which include the mitogen-activated protein kinases (MAPKs) ERK and p38, the phosphoinositide 3-kinases (PI3Ks), and the kinase mTOR. Although TCR stimulation activates the p38 path
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3016172e8ede29a21a8bac89a5d3082a
https://hdl.handle.net/1721.1/125782
https://hdl.handle.net/1721.1/125782