Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kayla J. Smith"'
Autor:
Kayla J, Smith, Sawyer, Cimaroli, Rory, Loo, Robert J, Havlik, Arlen D, Denny, Kristen A, Klement
Publikováno v:
Plastic & Reconstructive Surgery. 150:1293e-1299e
The appropriate use of narcotics for postoperative pain control is controversial because of potential medication-induced complications. The authors sought to determine the effects of narcotics in the pediatric population following cranial vault remod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f031ef72750d567d0b82567400409ca
https://doi.org/10.1097/prs.0000000000009696
https://doi.org/10.1097/prs.0000000000009696
Autor:
Gijs Rikken, Kayla J. Smith, Noa J.M. van den Brink, Jos P.H. Smits, Krishne Gowda, Angela Alnemri, Gulsum E. Kuzu, Iain A. Murray, Jyh-Ming Lin, Jos G.A. Smits, Ivonne M. van Vlijmen-Willems, Shantu G. Amin, Gary H. Perdew, Ellen H. van den Bogaard
Publikováno v:
Biochemical Pharmacology, 208
Therapeutic aryl hydrocarbon receptor (AHR) modulating agents gained attention in dermatology as non-steroidal anti-inflammatory drugs that improve skin barrier properties. By exploiting AHR's known ligand promiscuity, we generated novel AHR modulati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7172d2666ec03b70eb38539132641e5
https://hdl.handle.net/2066/290126
https://hdl.handle.net/2066/290126
Autor:
Shantu Amin, Krishne Gowda, Troy D. Hubbard, Kayla J. Smith, Iain A. Murray, Tejas S. Lahoti, Guray Kuzu, Gulsum E. Muku, Gary H. Perdew, Michael A. Podolsky
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology
The Ah receptor (AHR) has been shown to exhibit both inflammatory and anti-inflammatory activity in a context-specific manner. In vivo macrophage-driven acute inflammation models were utilized here to test whether the selective Ah receptor modulator
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e30eae3f1244f623a71b0116bcc9f71
https://doi.org/10.1038/labinvest.2017.92
https://doi.org/10.1038/labinvest.2017.92
Autor:
Dhimant Desai, Kayla J. Smith, Krishne Gowda, Iain A. Murray, Gulsum E. Muku, Adam B. Glick, Shantu Amin, Gary H. Perdew, Jacob A. Boyer
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 160(1)
Chemokines are components of the skin microenvironment, which enable immune cell chemotaxis. Traditionally, transcription factors involved in inflammatory signaling (eg, NFκB) are important mediators of chemokine expression. To what extent xenobioti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0bb2d775ef3cef3221fe613ddc7e817
https://pubmed.ncbi.nlm.nih.gov/28973351
https://pubmed.ncbi.nlm.nih.gov/28973351
Publikováno v:
Toxicology. 394
The mouse strain SKH1 is widely used in skin research due to its hairless phenotype and intact immune system. Due to the complex nature of aryl hydrocarbon receptor (AHR) function in the skin, the development of additional in vivo models is necessary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6015dc1239ef94da498d7951c33a2c8
https://pubmed.ncbi.nlm.nih.gov/29197551
https://pubmed.ncbi.nlm.nih.gov/29197551
Autor:
Kaarthik John, Shantu Amin, Gowdahalli Krishnegowda, Kayla J. Smith, Brett C. DiNatale, Gary H. Perdew
Publikováno v:
Molecular Cancer Research. 10:1369-1379
The aryl hydrocarbon receptor (AhR) has been shown to play a role in an increasing number of cellular processes. Recent reports have linked the AhR to cell proliferation, cytoskeletal arrangement, and tumor invasiveness in various tumor cell types. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6ef8c07e70c66dadacee2586e25c79a
https://doi.org/10.1158/1541-7786.mcr-12-0216
https://doi.org/10.1158/1541-7786.mcr-12-0216
Identification of a high-affinity ligand that exhibits complete aryl hydrocarbon receptor antagonism
Autor:
William H. Bisson, Gary H. Perdew, Michael P. Cooke, John Tellew, Siva Kumar Kolluri, Anthony E. Boitano, Rachel Tanos, Kayla J. Smith, Iain A. Murray
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 338(1)
The biological functions of the aryl hydrocarbon receptor (AHR) can be delineated into dioxin response element (DRE)-dependent or -independent activities. Ligands exhibiting either full or partial agonist activity, e.g., 2,3,7,8-tetrachlorodibenzo-p-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75022dfaf89266512bfdbdeeb37c4c72
https://pubmed.ncbi.nlm.nih.gov/21493753
https://pubmed.ncbi.nlm.nih.gov/21493753