Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Kayla F. Goliwas"'
Autor:
Shaheer Ahmad, Sierra Single, Yuelong Liu, Kenneth P. Hough, Yong Wang, Victor J. Thannickal, Mohammad Athar, Kayla F. Goliwas, Jessy S. Deshane
Publikováno v:
Antioxidants, Vol 13, Iss 8, p 978 (2024)
Exposure to heavy metals (HMs) is often associated with inflammation and cell death, exacerbating respiratory diseases including asthma. Most inhaled particulate HM exposures result in the deposition of HM-bound fine particulate matter, PM2.5, in pul
Externí odkaz:
https://doaj.org/article/d607257caa89471f9b00c2e471025d23
Autor:
Rabisa J. Khan, Sierra L. Single, Christopher S. Simmons, Mohammad Athar, Yuelong Liu, Sandeep Bodduluri, Paul V. Benson, Kayla F. Goliwas, Jessy S. Deshane
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionThe SARS-CoV-2 mediated COVID-19 pandemic has impacted millions worldwide. Hyper-inflammatory processes, including cytokine storm, contribute to long-standing tissue injury and damage in COVID-19. The metabolism of sphingolipids as regula
Externí odkaz:
https://doaj.org/article/985505055dd346e79bc00c0ebd3d84d0
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Sphingolipids are bioactive lipids involved in the regulation of cell survival, proliferation, and the inflammatory response. The SphK/S1P/S1PR pathway (S1P pathway) is a driver of many anti-apoptotic and proliferative processes. Pro-survival sphingo
Externí odkaz:
https://doaj.org/article/6c3d1f4038a74febbdc40bbd6434b98c
Autor:
Kayla F. Goliwas, Hannah M. Ashraf, Anthony M. Wood, Yong Wang, Kenneth P. Hough, Sandeep Bodduluri, Mohammad Athar, Joel L. Berry, Selvarangan Ponnazhagan, Victor J. Thannickal, Jessy S. Deshane
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Tumor-stromal interactions within the tumor microenvironment (TME) influence lung cancer progression and response to therapeutic interventions, yet traditional in vitro studies fail to replicate the complexity of these interactions. Herein, we develo
Externí odkaz:
https://doaj.org/article/90f97a9bf0e049c8b01cac94dcb42e54
Autor:
Kayla F. Goliwas, Anthony M. Wood, Young-il Kim, Joel L. Berry, James M. Donahue, Jessy S. Deshane
Publikováno v:
Cancer Immunology Research. 10:B33-B33
The tumor microenvironment is a key regulator of tumor biology and response to therapeutic intervention, with intercellular communication between tumor and stromal cells regulating growth and progression. While two dimensional cultures are commonly u
Autor:
Yong Wang, Derek Van Vessem, Jessy S. Deshane, Kayla F. Goliwas, Selvarangan Ponnazhagan, Sultan Tousif, Paige E. Severino, Hong Wang, Roy P. Koomullil, Kenneth P. Hough, Andra R. Frost, Joel L. Berry
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology
Breast cancer (BCa) proliferates within a complex, three-dimensional microenvironment amid heterogeneous biochemical and biophysical cues. Understanding how mechanical forces within the tumor microenvironment (TME) regulate BCa phenotype is of great
Publikováno v:
Journal of Tissue Engineering, Vol 7 (2016)
Breast carcinomas are complex, three-dimensional tissues composed of cancer epithelial cells and stromal components, including fibroblasts and extracellular matrix. In vitro models that more faithfully recapitulate this dimensionality and stromal mic
Externí odkaz:
https://doaj.org/article/0de51411eb0746fa990edd8f32f95eed
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Frontiers in Physiology
Frontiers in Physiology
Sphingolipids are bioactive lipids involved in the regulation of cell survival, proliferation, and the inflammatory response. The SphK/S1P/S1PR pathway (S1P pathway) is a driver of many anti-apoptotic and proliferative processes. Pro-survival sphingo
Autor:
Jessy S. Deshane, Mohammad Athar, Kayla F. Goliwas, Selvarangan Ponnazhagan, Victor J. Thannickal, Anthony M. Wood, Sandeep Bodduluri, Joel L. Berry, Kenneth P. Hough, Yong Wang, Hannah M Ashraf
Publikováno v:
Frontiers in Oncology
Frontiers in Oncology, Vol 11 (2021)
Frontiers in Oncology, Vol 11 (2021)
Tumor-stromal interactions within the tumor microenvironment (TME) influence lung cancer progression and response to therapeutic interventions, yet traditional in vitro studies fail to replicate the complexity of these interactions. Herein, we develo
Autor:
Jessy S. Deshane, Selvarangan Ponnazhagan, Behnam Tehrani, Kayla F. Goliwas, Yong Wang, Roy P. Koomullil, Joel L. Berry
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Frontiers in Medicine
Frontiers in Medicine
Cellular exosome-mediated crosstalk in tumor microenvironment (TME) is a critical component of anti-tumor immune responses. In addition to particle size, exosome transport and uptake by target cells is influenced by physical and physiological factors