Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Kayla A Jara"'
Autor:
Kayla A Jara, Nikolaus M Loening, Patrick N Reardon, Zhen Yu, Prajna Woonnimani, Coban Brooks, Cat H Vesely, Elisar J Barbar
Publikováno v:
eLife, Vol 11 (2022)
As the only major retrograde transporter along microtubules, cytoplasmic dynein plays crucial roles in the intracellular transport of organelles and other cargoes. Central to the function of this motor protein complex is dynein intermediate chain (IC
Externí odkaz:
https://doaj.org/article/8fc3ccdb65874b4c917186036545a17d
Autor:
Evelyn L Eastwood, Kayla A Jara, Susanne Bornelöv, Marzia Munafò, Vasileios Frantzis, Emma Kneuss, Elisar J Barbar, Benjamin Czech, Gregory J Hannon
Publikováno v:
eLife, Vol 10 (2021)
In animal gonads, the PIWI-interacting RNA (piRNA) pathway guards genome integrity in part through the co-transcriptional gene silencing of transposon insertions. In Drosophila ovaries, piRNA-loaded Piwi detects nascent transposon transcripts and ins
Externí odkaz:
https://doaj.org/article/8c72a5d9b9b2465db0cee631acd9807f
Autor:
Douglas R. Walker, Kayla A. Jara, Amber D. Rolland, Coban Brooks, Wendy Hare, Andrew K. Swansiger, Patrick N. Reardon, James S. Prell, Elisar J. Barbar
Publikováno v:
Biomolecules, Vol 13, Iss 3, p 404 (2023)
LC8, a ubiquitous and highly conserved hub protein, binds over 100 proteins involved in numerous cellular functions, including cell death, signaling, tumor suppression, and viral infection. LC8 binds intrinsically disordered proteins (IDPs), and alth
Externí odkaz:
https://doaj.org/article/8501563212024d60b3f2005ca59a64c0
Autor:
Kayla A, Jara, Elisar J, Barbar
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2623
Cytoplasmic dynein complexes play crucial roles in intracellular transport of cellular organelles. While the motor domain of dynein is well characterized by techniques such as X-ray crystallography and cryo-electron microscopy (Cryo-EM), structural r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ea647c9cb4e12baf367d9c91abd5b55c
https://pubmed.ncbi.nlm.nih.gov/36602690
https://pubmed.ncbi.nlm.nih.gov/36602690
Autor:
Kayla A. Jara, Elisar J. Barbar
Publikováno v:
Methods in Molecular Biology ISBN: 9781071629574
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a39a78365edee449095ab39ff6325696
https://doi.org/10.1007/978-1-0716-2958-1_15
https://doi.org/10.1007/978-1-0716-2958-1_15
Publikováno v:
Biophys J
Cytoplasmic dynein is a eukaryotic motor protein complex that, along with its regulatory protein dynactin, is essential to the transport of organelles within cells. The interaction of dynein with dynactin is regulated by binding between the intermedi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad9a85b42959adc899c4b6a69ac7b139
https://doi.org/10.1016/j.bpj.2020.07.023
https://doi.org/10.1016/j.bpj.2020.07.023
Autor:
James S. Prell, Hanh T.M. Hoang, Delaney A. Smith, Kayla A. Jara, Elisar Barbar, Patrick N. Reardon, Amber D. Rolland
Publikováno v:
J Biol Chem
Dynein light chain 8 (LC8) interacts with intrinsically disordered proteins (IDPs) and influences a wide range of biological processes. It is becoming apparent that among the numerous IDPs that interact with LC8, many contain multiple LC8-binding sit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a2b058a46c9c548ffa154a4f5e6cd63
https://doi.org/10.1074/jbc.ra119.011653
https://doi.org/10.1074/jbc.ra119.011653
Autor:
Kirsten J. Lampi, Elisar Barbar, Calvin Vetter, Kayla A. Jara, Heather M. Forsythe, Larry L. David, Patrick N. Reardon
Publikováno v:
Biochemistry. 58:4112-4124
Deamidation is a major age-related modification in the human lens that is highly prevalent in crystallins isolated from the insoluble fraction of cataractous lenses and also causes protein aggregation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1e88b1ffc66e4ce49fc2ee038a60c38
https://doi.org/10.1021/acs.biochem.9b00593
https://doi.org/10.1021/acs.biochem.9b00593
Autor:
Vasileios Frantzis, Susanne Bornelöv, Benjamin Czech, Emma Kneuss, Kayla A. Jara, Marzia Munafò, Evelyn L Eastwood, Gregory J. Hannon, Elisar Barbar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09bcc9be040db04610ffa692c530d516
https://doi.org/10.7554/elife.65557.sa2
https://doi.org/10.7554/elife.65557.sa2