Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Kaye D. Speicher"'
Autor:
Angela C. Brown, Kathleen Boesze-Battaglia, Hsin-Yao Tang, Nestor Mas Gomez, Margaret E Duszyk, Nataliya V. Balashova, Kaye D. Speicher, Edward T. Lally
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 10, p e0205871 (2018)
PLoS ONE, Vol 13, Iss 10, p e0205871 (2018)
The oral bacterium, Aggregatibacter actinomycetemcomitans, which is associated with localized aggressive periodontitis, as well as systemic infections including endocarditis, produces numerous virulence factors, including a repeats-in-toxin (RTX) pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94140eee1fe2068eb59d907d26299b37
http://europepmc.org/articles/PMC6193665
http://europepmc.org/articles/PMC6193665
Autor:
Esther N. Pesciotta, Kaye D. Speicher, Sandra L. Harper, Avik Basu, David W. Speicher, Abhijit Chakrabarti
Publikováno v:
Journal of Proteomics. 128:298-305
Erythrocyte shape and membrane integrity is imparted by the membrane skeleton, which can be isolated as a Triton X-100 insoluble structure that retains the biconcave shape of intact erythrocytes, indicating isolation of essentially intact membrane sk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59ce369f1c2026e96bcc9cd450b8735c
https://doi.org/10.1016/j.jprot.2015.08.004
https://doi.org/10.1016/j.jprot.2015.08.004
Autor:
Kaye D. Speicher, David W. Speicher, Donita Garland, James M. Harnly, Rosario Fernandez-Godino, Eric A. Pierce, Inderjeet Kaur, John D. Lambris
Publikováno v:
Human Molecular Genetics. 23:52-68
Macular degenerations, inherited and age related, are important causes of vision loss. Human genetic studies have suggested perturbation of the complement system is important in the pathogenesis of age-related macular degeneration. The mechanisms und
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5b0f0c682ed5f9d4f8a40ac63bd3fab
https://doi.org/10.1093/hmg/ddt395
https://doi.org/10.1093/hmg/ddt395
Autor:
Souvik Bhattacharjee, Robert V. Stahelin, David W. Speicher, Kaye D. Speicher, Kasturi Haldar
Publikováno v:
Cell. 148(1-2):201-212
SummaryHundreds of effector proteins of the human malaria parasite Plasmodium falciparum constitute a “secretome” carrying a host-targeting (HT) signal, which predicts their export from the intracellular pathogen into the surrounding erythrocyte.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcbe25d0b65d5a3b32dc18df0385ea9b
Publikováno v:
Journal of Biological Chemistry. 285:33265-33280
Many actin-binding proteins have been shown to possess multiple activities to regulate filament dynamics. Tropomodulins (Tmod1–4) are a conserved family of actin filament pointed end-capping proteins. Our previous work has demonstrated that Tmod3 b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d11f63c3fec9b9950e9b25af10b2c5b
https://doi.org/10.1074/jbc.m110.144873
https://doi.org/10.1074/jbc.m110.144873
Autor:
Kaye D. Speicher, Kasturi Haldar, David W. Speicher, Pamela A. Tamez, Souvik Bhattacharjee, Andrew R. Osborne
Publikováno v:
Molecular and Biochemical Parasitology. 171:25-31
During the blood stage of its lifecycle, the malaria parasite resides and replicates inside a membrane vacuole within its host cell, the human erythrocyte. The parasite exports many proteins across the vacuole membrane and into the host cell cytoplas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::108e779f884568494c6b05f97f71e1df
https://doi.org/10.1016/j.molbiopara.2010.01.003
https://doi.org/10.1016/j.molbiopara.2010.01.003
Autor:
Michael J. Ellison, Lei Li, John J.M. Bergeron, David W. Speicher, Marina Hincapie, Sjoerd van der Post, Peter J. Sheffield, Catherine C. L. Wong, Thomas A. Beardslee, P. D. Semchuk, Sean C. Bendall, Daniel Cociorva, Wantao Ying, Caroline May, Seul Ki Jeong, Wei Jia, Philip C. Andrews, Steve A. Carr, Benoit Houle, Robert L. Moritz, Lennart Martens, Ana Lopez-Campistrous, Martin Eisenacher, Alexander W. Bell, Raju Kucherlapati, Ron Beavis, Xiaohong Qian, Fuchu He, Brian L. Hood, John R. Yates, Tommy Nilsson, Kieran Wynne, Radoslav Goldman, Vivian Nguyen, Katy Williams, Giuliano Elia, Rudolf Grimm, Salvatore Sechi, Christoph H. Borchers, Yanming An, Masanori Fujimoto, Catherine E. Au, Young Ki Paik, Mahbod Hajivandi, Peipei Ping, Yun Cai, Pavel Metalnikov, Christine A. Miller, Christian Stephan, Wenhong Zhu, Rushdy Ahmad, Marshall Pope, Jinglan Wang, Thomas P. Conrads, Eric W. Deutsch, Min-Seok Kwon, Gilles A. Lajoie, Michael J. Dunn, Guy G. Poirier, Juan Antonio Vizcaíno, William L. Bigbee, Lina Song, John R. Strahler, Sang Yun Cho, Phillip Gray, Craig A. Dorschel, William S. Hancock, Tony Pawson, Kenneth C. Parker, Kaye D. Speicher, Angela K. Walker, Paul F. Predki, Heather Patsiouras, Richard J. Simpson, Thomas Chappell, Kenneth E. Hung, Qing Zhang, Samir M. Hanash, Eugene A. Kapp, Yueju Wang, Katrin Marcus, Jason J. Struthers, Gavin Meredith, Junying Wei, Yangjun Zhang, Sylvie Bourassa, Elisabet Carlsohn, Jayson A. Falkner, Derek Smith, An Sung Chung, Sylvie Laboissiere, Helmut E. Meyer, Hong Wang, Jeffrey W. Smith, Hyoung Joo Lee, David A. Sarracino, Elmar Langenfeld, Kazuyuki Nakamura, Robert E. Kearney, Bing Yang, Bryan Krastins, Majlinda Kullolli
Publikováno v:
Nature methods
Biochemistry Publications
Biochemistry Publications
We carried out a test sample study to try to identify errors leading to irreproducibility, including incompleteness of peptide sampling, in LC-MS-based proteomics. We distributed a test sample consisting of an equimolar mix of 20 highly purified reco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4b5e903d9691deb1dd901076a5b4974
https://doi.org/10.1038/nmeth.1333
https://doi.org/10.1038/nmeth.1333
Autor:
David W. Speicher, Edward D. Karoly, Lucia R. Languino, Stephanie M. J. Fliedner, James F. Powers, Huan Wang, Andrew V. Kossenkov, Kaye D. Speicher, Alessia Angelin, Ryan D. Michalek, Young Chan Chae, Karel Pacak, Arthur S. Tischler, Dario C. Altieri, Douglas C. Wallace, Sofia Lisanti
Publikováno v:
Nature Communications. 6
Nature Communications 4: Article number: 2139 (2013); Published 10 July 2013; Updated 18 June 2015. This article was published without any declaration of competing financial interests. A revised competing financial interests statement is provided bel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf534cf63587069d162226764e63762f
https://doi.org/10.1038/ncomms8605
https://doi.org/10.1038/ncomms8605
Autor:
Travis Harrison, Sean C. Murphy, Benjamin U. Samuel, Marion E. Reid, Michael J. A. Tanner, Philip S. Low, David W. Speicher, Narla Mohandas, Kasturi Haldar, Rainer Prohaska, Kaye D. Speicher
Publikováno v:
Blood. 103:1920-1928
Infection of human erythrocytes by the apicomplexan malaria parasite Plasmodium falciparum results in endovacuolar uptake of 4 host proteins that reside in erythrocyte detergent-resistant membranes (DRMs). Whether this vacuolar transport reflects sel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38cf7c3a51afffb3a235332e3319866d
https://doi.org/10.1182/blood-2003-09-3165
https://doi.org/10.1182/blood-2003-09-3165
Autor:
Daniela Santoli, David W. Speicher, Xun Zuo, Kaye D. Speicher, Peter Hembach, Lynn A. Echan, Hsin Yao Tang
Publikováno v:
ELECTROPHORESIS. 22:1603-1615
The number of unique protein species in proteomes from a single mammalian cell type is not well defined but is likely to be at least 10000-20000. Since standard-size two-dimensional gels typically resolve only about 1500 to 3000 spots, they merely an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::770457ca9ee7ae7ad1f52b201ecd9743
https://doi.org/10.1002/1522-2683(200105)22:9<1603::aid-elps1603>3.0.co
https://doi.org/10.1002/1522-2683(200105)22:9<1603::aid-elps1603>3.0.co